scholarly journals Prdm12 Is Induced by Retinoic Acid and Exhibits Anti-proliferative Properties through the Cell Cycle Modulation of P19 Embryonic Carcinoma Cells

2013 ◽  
Vol 38 (2) ◽  
pp. 197-206 ◽  
Author(s):  
Chia-Ming Yang ◽  
Yoichi Shinkai
Keyword(s):  
Cell Cycle ◽  
Retinoic Acid ◽  
Carcinoma Cells ◽  
Embryonic Carcinoma ◽  
Cell Cycle Modulation ◽  
Embryonic Carcinoma Cells

scholarly journals Retinoic Acid Induces Differentiation of Mouse F9 Embryonic Carcinoma Cell by Modulating the miR-485 Targeting of Abhd2

2019 ◽  
Vol 20 (9) ◽  
pp. 2071 ◽  
Author(s):  
Mengying Yu ◽  
Lei Zhang ◽  
Yingxiang Liu ◽  
Defu Liu ◽  
Zekun Guo
Keyword(s):  
Retinoic Acid ◽  
Cell Differentiation ◽  
Carcinoma Cell ◽  
Carcinoma Cells ◽  
Extracellular Signal Regulated Kinase ◽  
Embryonic Carcinoma ◽  
Extracellular Signal ◽  
Embryonic Carcinoma Cells ◽  
Embryonic Carcinoma Cell ◽  
Mediate Cell

Retinoic acid (RA) plays a key role in pluripotent cell differentiation. In F9 embryonic carcinoma cells, RA can induce differentiation towards somatic lineages via the Ras-extracellular signal-regulated kinase (Ras/Erk) pathway, but the mechanism through which it induces the Erk1/2 phosphorylation is unclear. Here, we show that miR-485 is a positive regulator that targets α/β-hydrolase domain-containing protein 2 (Abhd2), which can result in Erk1/2 phosphorylation and triggers differentiation. RA up-regulates miR-485 and concurrently down-regulates Abhd2. We verified that Abhd2 is targeted by miR-485 and they both can influence the phosphorylation of Erk1/2. In summary, RA can mediate cell differentiation by phosphorylating Erk1/2 via miR-485 and Abhd2.

scholarly journals Disassociation of MAPK Activation and c-Fos Expression in F9 Embryonic Carcinoma Cells following Retinoic Acid-induced Endoderm Differentiation

2001 ◽  
Vol 276 (34) ◽  
pp. 32094-32100 ◽  
Author(s):  
Elizabeth R. Smith ◽  
Jennifer L. Smedberg ◽  
Malgorzata E. Rula ◽  
Thomas C. Hamilton ◽  
Xiang-Xi Xu
Keyword(s):  
Retinoic Acid ◽  
Carcinoma Cells ◽  
Mapk Activation ◽  
Endoderm Differentiation ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cells ◽  
Fos Expression

scholarly journals SC1 inhibits the differentiation of F9 embryonic carcinoma cells induced by retinoic acid

2018 ◽  
Vol 50 (8) ◽  
pp. 793-799
Author(s):  
Yingxiang Liu ◽  
Xuexue Ren ◽  
Jie Ke ◽  
Yan Zhang ◽  
Qing Wei ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Carcinoma Cells ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cells

scholarly journals Tributyltin induces G2/M cell cycle arrest via NAD+-dependent isocitrate dehydrogenase in human embryonic carcinoma cells

2016 ◽  
Vol 41 (2) ◽  
pp. 207-215 ◽  
Author(s):  
Miki Asanagi ◽  
Shigeru Yamada ◽  
Naoya Hirata ◽  
Hiroshi Itagaki ◽  
Yaichiro Kotake ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Isocitrate Dehydrogenase ◽  
Carcinoma Cells ◽  
M Cell ◽  
Embryonic Carcinoma ◽  
Cycle Arrest ◽  
Embryonic Carcinoma Cells

scholarly journals Sox6 overexpression causes cellular aggregation and the neuronal differentiation of P19 embryonic carcinoma cells in the absence of retinoic acid

FEBS Letters ◽  
2004 ◽  
Vol 560 (1-3) ◽  
pp. 192-198 ◽  
Author(s):  
Michiko Hamada-Kanazawa ◽  
Kyoko Ishikawa ◽  
Kaori Nomoto ◽  
Takako Uozumi ◽  
Yuichi Kawai ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Neuronal Differentiation ◽  
Carcinoma Cells ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cells ◽  
Cellular Aggregation

LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells

2017 ◽  
Vol 119 (1) ◽  
pp. 314-326 ◽  
Author(s):  
Chia-Yih Wang ◽  
Yu-Han Hong ◽  
Jhih-Siang Syu ◽  
Yung-Chieh Tsai ◽  
Xiu-Ying Liu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Progression ◽  
Carcinoma Cells ◽  
Microtubule Nucleation ◽  
Cycle Progression ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cells
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