scholarly journals Association between  4 integrin cytoplasmic tail and non-muscle myosin IIA regulates cell migration

2011 ◽  
Vol 124 (3) ◽  
pp. 483-492 ◽  
Author(s):  
L. A. R. Rosado ◽  
T. A. Horn ◽  
S. C. McGrath ◽  
R. J. Cotter ◽  
J. T. Yang
Keyword(s):  
Cell Migration ◽  
Cytoplasmic Tail ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail

2012 ◽  
Vol 44 (7) ◽  
pp. 1153-1165 ◽  
Author(s):  
Armen Petrosyan ◽  
Mohamed F. Ali ◽  
Shailendra Kumar Verma ◽  
Helen Cheng ◽  
Pi-Wan Cheng
Keyword(s):  
Endoplasmic Reticulum ◽  
Cytoplasmic Tail ◽  
Myosin Iia ◽  
Muscle Myosin

Abstract 5136: Sulfiredoxin promotes cell migration through direct interaction with non muscle myosin IIa

2010 ◽  
Author(s):  
Robert Bowers ◽  
Danyelle M. Townsend ◽  
Yefim Manevich ◽  
Kenneth D. Tew
Keyword(s):  
Cell Migration ◽  
Direct Interaction ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA

2007 ◽  
Vol 44 (6) ◽  
pp. 387-392 ◽  
Author(s):  
M. Martinelli ◽  
M. Di Stazio ◽  
L. Scapoli ◽  
J. Marchesini ◽  
F. Di Bari ◽  
...  
Keyword(s):  
Cleft Palate ◽  
Heavy Chain ◽  
Cleft Lip ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals Author response: Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA

2019 ◽  
Author(s):  
Míriam Javier-Torrent ◽  
Sergi Marco ◽  
Daniel Rocandio ◽  
Maria Pons-Vizcarra ◽  
Peter W Janes ◽  
...  
Keyword(s):  
Author Response ◽  
Axon Elongation ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals The tumor suppressor capability of p53 is dependent on non-muscle myosin IIA function in head and neck cancer

Oncotarget ◽  
2017 ◽  
Vol 8 (14) ◽  
pp. 22991-23007 ◽  
Author(s):  
Sonya D. Coaxum ◽  
Jessica Tiedeken ◽  
Elizabeth Garrett-Mayer ◽  
Jeffrey Myers ◽  
Steven A. Rosenzweig ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Tumor Suppressor ◽  
Head And Neck ◽  
Neck Cancer ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals MYH9: Structure, functions and role of non-muscle myosin IIA in human disease

Gene ◽  
2018 ◽  
Vol 664 ◽  
pp. 152-167 ◽  
Author(s):  
Alessandro Pecci ◽  
Xuefei Ma ◽  
Anna Savoia ◽  
Robert S. Adelstein
Keyword(s):  
Human Disease ◽  
Structure Functions ◽  
Myosin Iia ◽  
Muscle Myosin

scholarly journals Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Mélanie Chabaud ◽  
Mélina L. Heuzé ◽  
Marine Bretou ◽  
Pablo Vargas ◽  
Paolo Maiuri ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Cell Migration ◽  
Mhc Class Ii ◽  
Myosin Ii ◽  
General Mechanism ◽  
Specific Cell ◽  
Cell Functions ◽  
Antigen Capture ◽  
Cell Front ◽  
Myosin Iia

Abstract The immune response relies on the migration of leukocytes and on their ability to stop in precise anatomical locations to fulfil their task. How leukocyte migration and function are coordinated is unknown. Here we show that in immature dendritic cells, which patrol their environment by engulfing extracellular material, cell migration and antigen capture are antagonistic. This antagonism results from transient enrichment of myosin IIA at the cell front, which disrupts the back-to-front gradient of the motor protein, slowing down locomotion but promoting antigen capture. We further highlight that myosin IIA enrichment at the cell front requires the MHC class II-associated invariant chain (Ii). Thus, by controlling myosin IIA localization, Ii imposes on dendritic cells an intermittent antigen capture behaviour that might facilitate environment patrolling. We propose that the requirement for myosin II in both cell migration and specific cell functions may provide a general mechanism for their coordination in time and space.

Abstract 4205: The role of non-muscle myosin IIA in HER2+ breast cancers

2020 ◽  
Author(s):  
Samar M. Alanazi ◽  
Rosalin Mishra ◽  
Long Yuan ◽  
Hima Patel ◽  
Joan Garrett
Keyword(s):  
Breast Cancers ◽  
Myosin Iia ◽  
Muscle Myosin
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