scholarly journals Physical and reported Subjective Health Status in 222 individuals with XY Disorder of Sex Development (DSD)

2021 ◽  
Author(s):  
Xin Li Gong ◽  
Klemens Raile ◽  
Jolanta Slowikowska-Hilczer ◽  
Catherine Pienkowski ◽  
Marcus Quinkler ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Health Status ◽  
Lumbar Spine ◽  
Estrogen Therapy ◽  
Disorders Of Sex Development ◽  
Density Lipoprotein ◽  
Subjective Health ◽  
Mineral Density ◽  
Subjective Health Status ◽  
Sex Development

Abstract Context Little is known about the physical health of individuals with 46,XY disorders of sex development (DSD). Objective To assess physical and reported subjective health of individuals with XY DSD. Design and methods As part of the dsd-LIFE study, patients with an XY DSD condition were analyzed in different diagnosis groups for metabolic parameters, comorbidities, metabolic syndrome, bone outcomes, and reported subjective health. Findings were evaluated by descriptive statistics. Results A total of 222 patients with XY DSD were included with a mean age of 28.8±12.2 years, mean height of 175.3±7.7 cm, mean weight of 74.3±20.0 kg and mean BMI of 24.1±6.0 kg/m 2. Obesity rate was not increased when descriptively compared to Eurostat data. Fourteen patients had metabolic syndrome (14/175; 8.0%). In descriptive comparison to data from the DECODE study and WHO, subjects fared better in the categories waist circumference, glucose, triglyceride, cholesterol and high-density lipoprotein. Of participants with available bone health data, 19/122 (15.6%) patients had a Z-score ≤ - 2.0 at lumbar spine indicating lowered bone mineral density (BMD). Mostly gonadectomized individuals with complete androgen insensitivity syndrome (CAIS) and no estrogen therapy had lowered BMD at lumbar spine. Individuals with XY DSD performed poorly in the category subjective health in descriptive comparison to Eurostat data. Conclusion Participants reported a lower subjective health status compared to Eurostat data but their overall metabolic health status was good. Decreased BMD at lumbar spine was especially present in gonadectomized individuals with CAIS and no estrogen therapy.

scholarly journals Weight Control in Postmenopausal Korean Patients with Osteoarthritis

2020 ◽  
Author(s):  
MunHee KIM
Keyword(s):  
Health Status ◽  
Food Intake ◽  
Weight Control ◽  
Density Lipoprotein ◽  
Subjective Health ◽  
Volume Reduction ◽  
Control Methods ◽  
Subjective Health Status ◽  
Hemodynamic Variables ◽  
Hs Crp

Background: Weight control is crucial for osteoarthritis management. This study investigated weight control methods in postmenopausal Korean osteoarthritis patients and examined their correlation with subjective health status and figure recognition, obesity, quality of life (QoL), and hemodynamic variables. Methods: One thousand six hundred and seventy-eight female postmenopausal osteoarthritis patients participated in the 2018 Korea National Health and Nutrition Examination Survey. A frequency analysis was conducted for weight control methods, and phi coefficients for crossover analyses or Cramer’s V coefficient were calculated to identify the relationships between weight-control-related variables and subjective health status and QoL. Using independent t-tests, we examined the relationships of weight control methods with hemodynamic variables. Results: Postmenopausal osteoarthritis patients’ preferred weight control methods were exercise, meal volume reduction, functional diet consumption, and the skipping of meals. Osteoarthritis patients who performed exercise demonstrated improved subjective figure recognition and health status, body weight, and recent 2- week discomfort, QoL, and hemodynamic variables (systolic blood pressure and fasting glucose, hemoglobin A1C, total cholesterol, high-density lipoprotein cholesterol, and high-sensitivity C-reactive protein [hs-CRP] levels). However, patients who attempted weight control by food volume reduction made relatively harder efforts to lose weight but were more likely to view themselves as obese, and demonstrated higher pain levels, anxiety/depression, and recent 2-week discomfort. Further, they exhibited lower triglyceride levels, as did patients who skipped meals. Conclusion: Overall, Korean postmenopausal osteoarthritis patients’ preferred weight control methods were exercise and reduced food intake. Although reduced food intake was effective for weight control, exercise improved mental health and hemodynamics, particularly inflammation (hs-CRP) levels.

scholarly journals Factors Affecting the Development of Metabolic Syndrome in Single-Person Households: A Sex-Stratified Analysis

2021 ◽  
Vol 13 (16) ◽  
pp. 9032
Author(s):  
Jui Kim ◽  
Hyoungshim Choi
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Logistic Regression ◽  
Health Status ◽  
Significant Risk ◽  
Subjective Health ◽  
Multiple Logistic Regression ◽  
Subjective Health Status ◽  
Single Person ◽  
Stratified Analysis

Various sociodemographic and behavioral health factors have been reported to influence the development of metabolic syndrome (Mets). In addition, the effects of various sociodemographic and health related characteristics on single-person households appear to be influenced by sex. Considering the surge in the number of single-person households globally, we conducted a sex-stratified analysis of the factors that affect the development of Mets among single-person Korean households. We used secondary data from the 2016–2018 Korea National Health and Nutrition Examination Survey (KNHANES) for this study. A total of 1830 participants (aged ≥19 years) without any missing data were analyzed in this study. The chi-square test and multiple logistic regression were used to analyze the study data. The results of the multiple logistic regression analysis showed that the significant risk factors for Mets in men were age, body mass index (BMI), subjective health status, subjective recognition of body shape, household income, and sleep hours, whereas age, BMI, subjective health status, exercise, and sleep hours were the significant risk factors for Mets in women. Specialized sex-specific health policies and programs are needed to reduce the prevalence of Mets in single-person households.

Differences in physical function and metabolic syndrome risk factors according to the level of physical activity in elderly Korean men: a pilot study

2020 ◽  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Physical Function ◽  
Vigorous Physical Activity ◽  
Density Lipoprotein ◽  
The Elderly ◽  
Berg Balance Scale ◽  
Lower Percentage ◽  
Mineral Density

Background and objective: Managing the decrease in physical function in the elderly is a major task in aging societies globally. Here, we aimed to compare the physical function and metabolic syndrome (MetS) risk factors according to levels of physical activity (PA). Material and methods: We measured PA in 77 elderly Korean men (74.21 ± 6.26 years old) with an accelerometer and recorded body composition, physical function, and MetS-related risk factors. Participants were divided into three groups based on daily moderate-vigorous physical activity (MVPA): low (under 60 min), middle (60-120 min), and high (over 120 min). The groups were compared using a one-way analysis of variance and the Scheffe post hoc test. Odds ratios (OR) were calculated by logistic regression analysis. Results: Significant differences were found between the groups for sedentary behavior time (P < 0.001), light PA (P < 0.05), moderate PA (P < 0.001), vigorous PA (P < 0.05), and total energy expenditure (P < 0.001). The high PA group showed a significantly lower percentage of body fat and fat mass and higher muscle mass than did the low and middle PA groups (P < 0.05). The 6-min walk test was significantly better in the high PA group than in the low and middle PA groups (P < 0.05). Grip strength and the Berg balance scale were also significantly better in the high PA group (P < 0.05). Bone mineral density (BMD) and high-density lipoprotein cholesterol (HDL-C) were significantly higher in the high PA group than in the low PA group (P < 0.05). Systolic blood pressure (SBP) was significantly higher in the middle PA group than in the low PA group (P < 0.05). Participants with more than three MetS criteria showed an OR of 0.09 (95% confidence interval 0.01-0.82) in the high PA group as compared with the low PA group (P < 0.05). Conclusions: Moderate-vigorous physical activity of more than 120 min daily showed better physical function and lower OR of MetS than did lower MVPA levels in elderly Korean men.

The Effect of Exercise Participation in Elderly on Subjective Health Status, Depression and Life Satisfication

2018 ◽  
Vol 26 (4) ◽  
pp. 495-500
Author(s):  
Younpyo Lee ◽  
Su-keun Park ◽  
Jae-ho Khil ◽  
Sungho Maeng ◽  
Jungwon Shin ◽  
...  
Keyword(s):  
Health Status ◽  
Subjective Health ◽  
Subjective Health Status ◽  
Exercise Participation

scholarly journals Health Status of Healthcare Professionals Working in an Institute for Chronically Ill Psychiatric Patients

2015 ◽  
Vol 66 (1) ◽  
pp. 43-52
Author(s):  
Katalin Nagyváradi ◽  
Zsuzsa Mátrai
Keyword(s):  
Health Status ◽  
Working Conditions ◽  
Healthcare Professionals ◽  
Psychiatric Patients ◽  
Chronically Ill ◽  
Subjective Health ◽  
The State ◽  
State Of Health ◽  
Subjective Health Status ◽  
Objective Health

AbstractSeveral research works in the related international literature on sociology and health sciences deal with the state of health in one selected population. In these studies, the chosen sample is often connected with special jobs, especially with healthcare professionals and their working conditions. These studies predominantly examine the self-rated subjective health status using questionnaires. There are others that assess the state of health based not only on self-rated subjective indicators, but also using objective data gained by measuring. Considering the international experiences, we chose a special population in our research – healthcare professionals working in an institute for chronically ill psychiatric patients. Our choice was influenced by the fact that we wanted to include their unique working conditions when exploring and assessing their health status. Moreover, our approach was to assess the objective state of health alongside the subjective factors, as our hypothesis was that the majority of the indicators presumably coincided. The data were collected with the help of three questionnaires and some indicators of the objective health statuses were measured. The findings were processed using the SPSS 17.0 mathematical-statistical software package. Following the descriptive statistics, we applied hierarchic cluster-analysis based on results of the WHOQOLD-BREF26 life-quality questionnaire, the WHO WBI-5 Well Being Index, and on the body composition analysis. The results show the objective and subjective health status of population and the factors that influenced it; the working conditions and the interpersonal contacts in the workplace. The conclusion was that in the examined population the subjective and objective health status doesn’t coincide.

scholarly journals The Prevalence of Metabolic Syndrome and Its Related Risk Complications among Koreans

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1755 ◽  
Author(s):  
Seung-Hoo Lee ◽  
Shuting Tao ◽  
Hak-Seon Kim
Keyword(s):  
Metabolic Syndrome ◽  
South Korea ◽  
Multivariate Logistic Regression Analysis ◽  
Subjective Health ◽  
Subjective Health Status ◽  
Nutrition Labelling ◽  
Health And Nutrition ◽  
Current Trends ◽  
Related Risk ◽  
And Gender

There is an increasing number of metabolic syndrome (MetS) patients worldwide, and there is no exception in South Korea. The risk complications of metabolic syndrome have been investigated by many previous research studies, while no data on any current trends of MetS are available. Therefore, the present study investigates the recent prevalence of MetS and its associated risk complications in Korean adults by using the Korean National Health and Nutrition Examination Survey (KNHANES). The Survey respondents (n = 4744) were adults over the age of 30, and they had participated in KNHANES 2016, which is a health survey of a national representative sample of non-institutionalized civilian South Koreans. The cross-tabulation analysis was applied to figure out the general characteristics impacting on the prevalence of MetS; furthermore, the odds ratios and 95% confidence intervals (CIs) using multivariate logistic regression analysis were presented for the risk complications of MetS. Findings from this study indicated that subjective health status, family structure, age, income level, use of nutrition labelling and gender showed significant connections with the prevalence of MetS. The risk diseases, stroke (OR = 2.174, 95% CI = 1.377–3.433, p < 0.01), myocardial infarction (MI) (OR = 2.667, 95% CI = 1.474–4.824, p < 0.01) and diabetes (OR = 6.533, 95% CI = 4.963, p < 0.001) were explored and verified attributable to the prevalence of MetS. The findings in this study suggest that sociodemographic characteristics-concentrated strategies are vital to prevent the prevalence of MetS in South Korea, and relative risk complications ought to be cautiously dealt with as well.

FRI0068 LIPID PROFILE AND BONE MINERAL DENSITY IN PATIENTS WITH RHEUMATOID ARTHRITIS: IS THERE AN ADDED RISK OF OSTEOPOROSIS?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 610.1-611
Author(s):  
B. Touil ◽  
H. Azzouzi ◽  
O. Lamkhanat ◽  
F. Chennouf ◽  
I. Linda
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Linear Regression ◽  
Femoral Neck ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Mineral Density ◽  
High Tc ◽  
High Concentrations

Background:Bone is a target in many inflammatory rheumatic diseases such as rheumatoid arthritis (RA). It has been supposed that an atherogenic lipid profile could be associated with lower bone mineral density (BMD) and vertebral fractures (VF).Objectives:We aimed to evaluate the relationship between the lipid profile, BMD and the presence of VF in RA patients.Methods:A cross sectional study was conducted in a population of 169 established RA. In each subject we evaluated the body mass index (BMI), tobacco use, alcohol consumption, presence of diabetes and high blood pression, lipid profile (total cholesterol (TC), High density lipoprotein cholesterol (HDLc), low density lipoprotein cholesterol (LDLc), triglycerides (TG), and VF. RA characteristics were also assessed (disease duration, disease activity score (DAS), auto antibodies, corticosteroid intake, and secondary sjogren’s syndrome). BMD was measured by dual energy X-ray absorptiometry (DXA) in lumbar spine and femoral neck. Logistic and linear regression were performed with SPSS 20, both BMD and VF were assessed as dependent variables.Results:The mean age was 55.5±11.9 years, with a female predominance (152 women). The average BMI was 26.79 ± 5.36. We had 24.3 % of hypertensive patients and 16.6 % of diabetics. The average lipid concentrations were 4.39±1 mmol/L for TC, 1.293±0.36 mmol/L for HDLc, 2.74±0.80 mmol/L for LDLc and 1.25±0.62 mmol/L for TG. At the linear regression there was no correlation between plasma lipid concentrations and BMD, whether at the lumbar spine or the femoral neck. However we found a significant correlation between VF and high TC concentrations (p=0.043, OR: 2.864, 95% IC [1.036-7.922]). At the multivariate regression, high TC levels were still associated with VF, adjusted in BMI, age and the duration of corticosteroid use (p=0.006, OR: 6.07, 95% CI[1.69- 21.77]). The same finding was observed between high concentrations of HDLc and the prevalence of VF adjusted in the same variables (p=0.006, OR: 197.01, 95% CI [4.64-8363.51]).Conclusion:Although there was no relation between lipid plasma levels and BMD in our population. There was a significant association between high concentrations of TC, HDLc and the prevalence of VF.Disclosure of Interests:None declared

Female Hyperandrogenism in Elite Sports and the Athletic Triad

2021 ◽  
Author(s):  
Angelica Lindén Hirschberg
Keyword(s):  
Female Athletes ◽  
Polycystic Ovary ◽  
Disorders Of Sex Development ◽  
Normal Female ◽  
Menstrual Disorders ◽  
Mineral Density ◽  
Energy Deficiency ◽  
Sex Development ◽  
Endocrine Disturbances ◽  
Increased Risk

AbstractEssential hyperandrogenism seems to be overrepresented in female elite athletes. This applies to mild forms such as polycystic ovary syndrome, as well as rare differences/disorders of sex development (DSD). The reason is likely a selection bias since there is increasing evidence that androgens are beneficial for athletic performance by potent anabolic effects on muscle mass and bone mass, and stimulation of erythropoiesis. XY DSD may cause a greatly increased production of testosterone in the male range, that is, 10 to 20 times higher than the normal female range. The established regulations concerning the eligibility of female athletes with severe hyperandrogenism to compete in the female classification remain controversial. The most common cause of menstrual disorders in female athletes, however, is probably an acquired functional hypothalamic disturbance due to energy deficiency in relation to energy expenditure, which could lead to low bone mineral density and increased risk of injury. This condition is particularly common in endurance and esthetic sports, where a lean body composition is considered an advantage for physical performance. It is important to carefully evaluate endocrine disturbances and menstrual disorders in athletes since the management should be specific according to the underlying cause.

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