scholarly journals Letter to the Editor: “Steroid Sex Hormones, Sex Hormone-Binding Globulin, and Diabetes Incidence in the Diabetes Prevention Program” by Mather K.J., et al

2015 ◽  
Vol 100 (12) ◽  
pp. L126-L127 ◽  
Author(s):  
Franck Mauvais-Jarvis
Keyword(s):  
Sex Hormones ◽  
Prevention Program ◽  
Diabetes Prevention ◽  
Diabetes Prevention Program ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Diabetes Incidence ◽  
Hormone Binding ◽  
Letter To The Editor ◽  
Steroid Sex Hormones

scholarly journals Sex Hormone Binding Globulin and Sex Steroids Among Premenopausal Women in the Diabetes Prevention Program

2013 ◽  
Vol 98 (7) ◽  
pp. 3049-3057 ◽  
Author(s):  
Catherine Kim ◽  
Xavier Pi-Sunyer ◽  
Elizabeth Barrett-Connor ◽  
Frankie B. Stentz ◽  
Mary Beth Murphy ◽  
...  
Keyword(s):  
Sex Steroids ◽  
Prevention Program ◽  
Diabetes Prevention ◽  
Premenopausal Women ◽  
Diabetes Prevention Program ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding

scholarly journals Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program

2020 ◽  
Vol 8 (2) ◽  
pp. e001841
Author(s):  
Vanita R Aroda ◽  
Costas A Christophi ◽  
Sharon L Edelstein ◽  
Leigh Perreault ◽  
Catherine Kim ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Lifestyle Intervention ◽  
Prevention Program ◽  
Diabetes Prevention ◽  
Diabetes Prevention Program ◽  
Diabetes Risk ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Intensive Lifestyle Intervention

IntroductionSex hormone binding globulin (SHBG) levels are reported to be inversely associated with diabetes risk. It is unknown whether diabetes prevention interventions increase SHBG and whether resultant changes in SHBG affect diabetes risk. The purpose of this analysis was to determine whether intensive lifestyle intervention (ILS) or metformin changed circulating SHBG and if resultant changes influenced diabetes risk in the Diabetes Prevention Program (DPP).Research design and methodsThis is a secondary analysis from the DPP (1996–2001), a randomized trial of ILS or metformin versus placebo on diabetes risk over a mean follow-up of 3.2 years. The DPP was conducted across 27 academic study centers in the USA. Men, premenopausal and postmenopausal women without hormone use in the DPP were evaluated. The DPP included overweight/obese persons with elevated fasting glucose and impaired glucose tolerance. Main outcomes measures were changes in SHBG levels at 1 year and risk of diabetes over 3 years.ResultsILS resulted in significantly higher increases (postmenopausal women: p<0.01) or smaller decrements (men: p<0.05; premenopausal women: p<0.01) in SHBG compared with placebo or metformin. Changes in SHBG were primarily attributable to changes in adiposity. There were no consistent associations of change in SHBG with the risk of diabetes by treatment arm or participant group.ConclusionsLifestyle intervention may be associated with favorable changes in circulating SHBG, which is largely due to changes in adiposity. Changes in circulating SHBG do not independently predict reductions in diabetes incidence.

The Relationship between Sex Hormones, Sex Hormone Binding Globulin and Peripheral Artery Disease in Older Persons

2011 ◽  
pp. P1-338-P1-338
Author(s):  
Chiara Cattabiani ◽  
Gianpaolo Ceda ◽  
Fulvio Lauretani ◽  
Stefania Bandinelli ◽  
Giulia Schiavi ◽  
...  
Keyword(s):  
Sex Hormones ◽  
Peripheral Artery Disease ◽  
Older Persons ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Peripheral Artery ◽  
Artery Disease ◽  
The Relationship

scholarly journals Alcohol Consumption in Relation to Plasma Sex Hormones, Prolactin, and Sex Hormone–Binding Globulin in Premenopausal Women

2014 ◽  
Vol 23 (12) ◽  
pp. 2943-2953 ◽  
Author(s):  
Kelly A. Hirko ◽  
Donna Spiegelman ◽  
Walter C. Willett ◽  
Susan E. Hankinson ◽  
A. Heather Eliassen
Keyword(s):  
Alcohol Consumption ◽  
Sex Hormones ◽  
Premenopausal Women ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding
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