TLC–MS Analysis of Carotenoids, Triterpenoids, and Flavanols in Plant Extracts and Dietary Supplements

2015 ◽  
pp. 305-326
Author(s):  
Irena Vovk ◽  
Alen Albreht
Keyword(s):  
Dietary Supplements ◽  
Plant Extracts ◽  
Ms Analysis

scholarly journals Morphological and pharmacokinetic properties of oral solid dietary supplements containing plant extracts

2016 ◽  
Vol 62 (3) ◽  
pp. 49-62
Author(s):  
Adrian Głogowski ◽  
Zbigniew Marczyński ◽  
Michał Krzysztof Kołodziejczyk ◽  
Jerzy Jambor ◽  
Marta Kinga Stefan ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Plant Extracts ◽  
Gum Arabic ◽  
High Hardness ◽  
Diffusion Method ◽  
Wet Granulation ◽  
Surface Erosion ◽  
Morphological Parameters ◽  
Disintegration Time ◽  
Original Shape

Summary Introduction: Dietary supplements are a good way to supplement the deficiency of certain micronutrients and organic components (therapeutic agents) in human body. They are most often available in concentrated form as tablets, capsules, powder or liquid. Objective: To investigate morphological parameters and the pharmaceutical availability of coated tablets – dietary supplements – that contain selected pharmacopeial titrated dry plant extracts. Methods: Testing of the effective time of the tablet surface erosion was performed in model acceptor fluids using pharmacopeial methods in static (Erweka apparatus) and dynamic (unlimited diffusion method) conditions. Furthermore, morphological parameters of tablets (the original shape of an ellipse) as well as their hardness were determined. Results: The effective erosion time was determined by conductometric method using carboxymethylcellulose sodium salt (NaCMC) contained in the tablet. The content of gum arabic and NaCMC in the tablet testifies that the granulate was produced using the “wet granulation” technique which resulted in high hardness of original, esthetic, elliptical tablets and in prolonged disintegration time (erosion). Conclusions: The used excipients: gum arabic and NaCMC for the production of the tested tablets containing selected dry plant extracts result in their high hardness. The tested dietary supplements are characterized by esthetic design, original shape, and prolonged disintegration time which affects the pharmaceutical availability.

P.1.c.063 LC -ESI-MS/MS analysis and screening of Russian plant extracts as a tool for discovery of new potential neuroprotectors

2011 ◽  
Vol 21 ◽  
pp. S289
Author(s):  
S. Klochkov ◽  
E. Shevtsova ◽  
A. Ermatova ◽  
O. Novikova ◽  
I. Bravova ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Esi Ms ◽  
Ms Analysis ◽  
Russian Plant

Thermospray LC-MS Analysis of Phenolic and Terpene Glycosides in Crude Plant Extracts

Planta Medica ◽  
1992 ◽  
Vol 58 (S 1) ◽  
pp. 591-592
Author(s):  
J.-L. Wolfender ◽  
M. Maillard ◽  
K. Hostettmann
Keyword(s):  
Plant Extracts ◽  
Ms Analysis

Determination of Oxalate Content in Herbal Remedies and Dietary Supplements Based on Plant Extracts

2016 ◽  
Vol 19 (2) ◽  
pp. 205-210 ◽  
Author(s):  
Roswitha Siener ◽  
Montserrat López-Mesas ◽  
Manuel Valiente ◽  
Francisco Blanco
Keyword(s):  
Dietary Supplements ◽  
Plant Extracts ◽  
Herbal Remedies

scholarly journals Evaluation of cytotoxicity, nutritional and antioxidative status of lyophilized plant extracts used in dietary supplements

2021 ◽  
Vol 26 (2) ◽  
pp. 2396-2405
Author(s):  
BIANCA-MARIA TIHAUAN ◽  
◽  
IOANA-CRISTINA MARINAS ◽  
CORALIA BLEOTU ◽  
GEORGIANA DOLETE ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Plant Extracts ◽  
Mental Stress ◽  
Vital Role ◽  
The Body ◽  
Immune Functions ◽  
Echinacea Angustifolia ◽  
Rosa Canina ◽  
Antioxidative Status ◽  
Immunomodulatory Properties

Immune functions are indispensable in defending the body against pathogens and thus play a vital role in maintaining health. Immune functions are disturbed by malnutrition, aging, physical and mental stress or unwanted lifestyle. Therefore, the intake of immunomodulatory dietary supplements is considered effective in improving immune functions and reducing the incidence of immunological disorders. The main focus of this study was to evaluate the antioxidative status of lyophilized plant extracts, such as rosehip (Rosa canina), sea buckthorn (Hippophae rhamnoides), echinacea (Echinacea angustifolia) and bilberries (Vaccinium myrtillus), their cytotoxicity and nutritional status, in order to effectively utilize them as ingredients in a dietary supplement with immunomodulatory properties.

scholarly journals Anti-helminthic Activity of Consolida orientalis (Gay) Schröd. on Caenorhabditis elegans Nematodes and Determination of Possible Active Ingredients

2021 ◽  
Vol 9 (8) ◽  
pp. 1593-1598
Author(s):  
Hulya Ozpinar
Keyword(s):  
Caenorhabditis Elegans ◽  
Plant Extracts ◽  
Aerial Part ◽  
Intestinal Parasites ◽  
Active Ingredients ◽  
Antiparasitic Activity ◽  
Ms Analysis ◽  
Hot And Humid Climates ◽  
Stem Extract

Helminthiasis is an important parasitic disease, many of which are zoonotic, particularly common in developing countries and, in countries with hot and humid climates. Intestinal parasites can cause significant manifestations at all levels of the gastrointestinal tract, as well as anemia and growth retardation. This study aims to demonstrate the anti-helminthic effect of Consolida orientalis on Caenorhabditis elegans, which is a helminth model, and introduce new chemotherapeutic candidate substances with anti-helminthic effect to the literature by identifying possible active ingredients with GC-MS analysis. In our study, flower, leaf, stem and aerial part plant extracts of Consolida orientalis were used at 40 mg/mL, 20 mg/mL, 10 mg/mL, 5 mg/mL, 2.5 mg/mL, 1.25 mg/mL concentrations. In addition, possible active ingredients found in plant extracts were determined by GC-MS analysis. As a result of the study, it was determined that the aerial part, leaf and stem extract of the first four concentrates (40 mg/mL, 20 mg/mL, 10 mg/mL, 5 mg/mL) of Consolida orientalis were more effective than pyrantel pamoate at a concentration of 5 mg/mL. According to our study findings, chemotherapeutics such as Dihidrocarvone and 2(3H)-Benzoxazolone with new antihelmintic-antiparasitic activity are thought to contribute to further research.

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