Vitamin E (D-Alpha-Tocopheryl-co-Poly(Ethylene Glycol) 1000 Succinate) Micelles-Superparamagnetic Iron Oxide Nanoparticles for Enhanced Thermotherapy and MRI

2014 ◽  
pp. 882-903
Keyword(s):  
Iron Oxide ◽  
Vitamin E ◽  
Ethylene Glycol ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals Synthesis of Superparamagnetic Iron Oxide Nanoparticles Modified with MPEG-PEI via Photochemistry as New MRI Contrast Agent

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Yancong Zhang ◽  
Lianying Zhang ◽  
Xinfeng Song ◽  
Xiangling Gu ◽  
Hanwen Sun ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Resonance ◽  
Ethylene Glycol ◽  
Iron Oxide Nanoparticles ◽  
Methyl Ether ◽  
Superparamagnetic Iron Oxide ◽  
Oxide Nanoparticles ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Glycol Methyl Ether

Novel method for synthesis of superparamagnetic iron oxide nanoparticles (SPIONs) coated with polyethylenimine (PEI) and modified with poly(ethylene glycol) methyl ether (MPEG), MPEG-PEI-SPIONs, was developed. PEI-SPIONs were successfully prepared in aqueous system via photochemistry, and their surface was modified with poly(ethylene glycol) methyl ether (MPEG). The so-obtained MPEG-PEI-SPIONs had a uniform hydrodynamic particle size of 34 nm. The successful coating of MPEG-PEI on the SPIONs was ascertained from FT-IR analysis, and the PEI and MPEG fractions in MPEG-PEI-SPIONs were calculated to account for 31% and 12%, respectively. Magnetic measurement revealed that the saturated magnetization of MPEG-PEI-SPIONs reached 46 emu/g and the nanoparticles showed the characteristic of being superparamagnetic. The stability experiment revealed that the MPEG-PEI modification improved the nanoparticles stability greatly.T2 relaxation measurements showed that MPEG-PEI-SPIONs show similarR2 value to the PEI-SPIONs. TheT2-weighted magnetic resonance imaging (MRI) of MPEG-PEI-SPIONs showed that the magnetic resonance signal was enhanced significantly with increasing nanoparticle concentration in water. These results indicated that the MPEG-PEI-SPIONs had great potential for application in MRI.

Structure and Properties of Iron Oxide Nanoparticles Encapsulated by Phospholipids with Poly(ethylene glycol) Tails

2007 ◽  
Vol 111 (49) ◽  
pp. 18078-18086 ◽  
Author(s):  
Eleonora V. Shtykova ◽  
Xinlei Huang ◽  
Nicholas Remmes ◽  
David Baxter ◽  
Barry Stein ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Ethylene Glycol ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Structure And Properties ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals Embedding of superparamagnetic iron oxide nanoparticles into membranes of well-defined poly(ethylene oxide)-block-poly(ε-caprolactone) nanoscale magnetovesicles as ultrasensitive MRI probes of membrane bio-degradation

2019 ◽  
Vol 7 (30) ◽  
pp. 4692-4705 ◽  
Author(s):  
Adeline Hannecart ◽  
Dimitri Stanicki ◽  
Luce Vander Elst ◽  
Robert N. Muller ◽  
Annie Brûlet ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Ethylene Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Polymer Vesicles ◽  
Nanoprecipitation Method ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

The present study reports the preparation of PEO-b-PCL polymer vesicles via a nanoprecipitation method and the loading of hydrophobically coated USPIO into the membrane of these nanovesicles, whose thickness was measured precisely by SANS.

Advantages of poly(vinyl phosphonic acid)-based double hydrophilic block copolymers for the stabilization of iron oxide nanoparticles

2016 ◽  
Vol 7 (41) ◽  
pp. 6391-6399 ◽  
Author(s):  
K. H. Markiewicz ◽  
L. Seiler ◽  
I. Misztalewska ◽  
K. Winkler ◽  
S. Harrisson ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Block Copolymers ◽  
Ethylene Glycol ◽  
Iron Oxide Nanoparticles ◽  
Phosphonic Acid ◽  
Oxide Nanoparticles ◽  
Poly Ethylene Glycol ◽  
Double Hydrophilic Block Copolymers ◽  
Vinylphosphonic Acid ◽  
Poly Ethylene

Poly(ethylene glycol)–poly(vinylphosphonic acid) double hydrophilic block copolymers were synthesized by RAFT/MADIX polymerization and used to prepare stable iron oxide nanoparticles.

A mussel-inspired chitooligosaccharide based multidentate ligand for highly stabilized nanoparticles

2015 ◽  
Vol 3 (18) ◽  
pp. 3730-3737 ◽  
Author(s):  
Chichong Lu ◽  
Min Kyu Park ◽  
Chenxin Lu ◽  
Young Haeng Lee ◽  
Kyu Yun Chai
Keyword(s):  
Iron Oxide ◽  
Ethylene Glycol ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Poly Ethylene Glycol ◽  
Multidentate Ligand ◽  
Poly Ethylene

A mussel-inspired poly(ethylene glycol)-grafted-chitooligosaccharide based multidentate ligand (ML) is designed for preparing robust biocompatible iron oxide nanoparticles. The successful in vivo MRI application confirmed their suitability for biomedical applications.

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