Photoluminescence of Gold Nanoparticles and Their Applications to Sensing and Cell Imaging

2012 ◽  
pp. 193-222
Soft Matter ◽  
2018 ◽  
Vol 14 (12) ◽  
pp. 2400-2410 ◽  
Author(s):  
Samira Malekmohammadi ◽  
Hassan Hadadzadeh ◽  
Hossein Farrokhpour ◽  
Zahra Amirghofran

A nanocarrier for curcumin targeted delivery and cell imaging was prepared by immobilization of gold NPs on the folic acid-modified dendritic mesoporous silica-coated reduced graphene oxide nanosheets.


2014 ◽  
Vol 50 (56) ◽  
pp. 7473-7476 ◽  
Author(s):  
Na Li ◽  
Huijun Yang ◽  
Wei Pan ◽  
Wei Diao ◽  
Bo Tang

A tumor mRNA-triggered nanocarrier was established for multimodal cancer cell imaging and therapy based on the gold nanoparticles functionalized with molecular beacons.


2014 ◽  
Vol 50 (99) ◽  
pp. 15696-15698 ◽  
Author(s):  
Yanchao Song ◽  
Zhe Wang ◽  
Lihong Li ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Cemil Boyoglu ◽  
Qingwen He ◽  
Gerold Willing ◽  
Seyhan Boyoglu-Barnum ◽  
Vida A. Dennis ◽  
...  

Gold nanoparticles (GNPs) are widely used in biological and clinical applications due to their favorable chemical and optical properties. GNPs can be used for drug delivery to targeted cells. In addition, GNPs serve as ideal probes for biological and cell imaging applications. Recent studies indicate that the size diversity of GNPs plays an important role in targeting cellular components for biomedical applications. In this study, we conducted a series of studies using different sizes of gold nanoparticles, including 3, 10, 25, and 50 nm, to determine the effect of size variations on their intracellular localizations. Our cytotoxicity studies of GNPs into the HEp-2 cells using MTT assay indicated that 3 nm GNPs possess the highest toxicity. We exposed HEp-2 cells with various sizes of gold nanoparticles for different time intervals (1, 2, 4, 12, and 24 h) followed by imaging using scanning electron microscope (SEM) and atomic force microscope (AFM). Our SEM and AFM results showed that, after 1 hr incubation, 3 and 10 nm gold nanoparticles entered the nucleus, whereas 25 and 50 nm particles accumulated around the nucleus. As the time of exposure increased, GNPs entered the cells and accumulated in the cytosol and nucleus based solely on their sizes.


Langmuir ◽  
2012 ◽  
Vol 28 (9) ◽  
pp. 4464-4471 ◽  
Author(s):  
Jie Gao ◽  
Xiangyi Huang ◽  
Heng Liu ◽  
Feng Zan ◽  
Jicun Ren

2017 ◽  
Vol 8 (5) ◽  
pp. 3980-3988 ◽  
Author(s):  
Xumeng Wu ◽  
Yu Jia Tan ◽  
Hui Ting Toh ◽  
Lan Huong Nguyen ◽  
Shu Hui Kho ◽  
...  

A targeting system with excellent targeting ability is constructed by incorporating carbohydrate-modified gold nanoparticles as vehicles and GSH-responsive species as the payload.


2014 ◽  
Vol 196 ◽  
pp. 306-313 ◽  
Author(s):  
Kássio M.G. Lima ◽  
Raimundo F. Araújo Junior ◽  
Aurigena A. Araujo ◽  
Ana Luiza C.S. Leitão Oliveira ◽  
Luiz H.S. Gasparotto

2009 ◽  
Vol 274 (2) ◽  
pp. 319-326 ◽  
Author(s):  
Jing-Liang Li ◽  
Lei Wang ◽  
Xiang-Yang Liu ◽  
Zhi-Ping Zhang ◽  
Hong-Chen Guo ◽  
...  

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