Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy

2014 ◽  
Vol 50 (99) ◽  
pp. 15696-15698 ◽  
Author(s):  
Yanchao Song ◽  
Zhe Wang ◽  
Lihong Li ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Hyaluronic Acid ◽  
Cell Imaging ◽  
Cresyl Violet

Hybrid photoactive nanomaterial composed of gold nanoparticles, pheophorbide-A and hyaluronic acid as a targeted bimodal phototherapy

2015 ◽  
Vol 23 (5) ◽  
pp. 474-484 ◽  
Author(s):  
Sung Hun Kang ◽  
Md Nafiujjaman ◽  
Md Nurunnabi ◽  
Li Li ◽  
Haseeb A. Khan ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Hyaluronic Acid ◽  
Pheophorbide A

Immobilization of gold nanoparticles on folate-conjugated dendritic mesoporous silica-coated reduced graphene oxide nanosheets: a new nanoplatform for curcumin pH-controlled and targeted delivery

Soft Matter ◽  
2018 ◽  
Vol 14 (12) ◽  
pp. 2400-2410 ◽  
Author(s):  
Samira Malekmohammadi ◽  
Hassan Hadadzadeh ◽  
Hossein Farrokhpour ◽  
Zahra Amirghofran
Keyword(s):  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Folic Acid ◽  
Mesoporous Silica ◽  
Reduced Graphene Oxide ◽  
Targeted Delivery ◽  
Cell Imaging ◽  
Graphene Oxide Nanosheets ◽  
Reduced Graphene ◽  
Gold Nps

A nanocarrier for curcumin targeted delivery and cell imaging was prepared by immobilization of gold NPs on the folic acid-modified dendritic mesoporous silica-coated reduced graphene oxide nanosheets.

scholarly journals Hyaluronic acid-based carbon dots for efficient gene delivery and cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (25) ◽  
pp. 15613-15624 ◽  
Author(s):  
Hai-Jiao Wang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
Tian-Ying Luo ◽  
Xi He ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Gene Delivery ◽  
Carbon Dots ◽  
Cell Imaging ◽  
Microwave Assisted ◽  
Efficient Gene ◽  
Microwave Assisted Method

Two polymers were used with no additives to directly construct multifunctional carbon dots by a microwave-assisted method for simultaneous gene delivery and cell imaging.

A tumour mRNA-triggered nanocarrier for multimodal cancer cell imaging and therapy

2014 ◽  
Vol 50 (56) ◽  
pp. 7473-7476 ◽  
Author(s):  
Na Li ◽  
Huijun Yang ◽  
Wei Pan ◽  
Wei Diao ◽  
Bo Tang
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Molecular Beacons ◽  
Cancer Cell Imaging ◽  
Tumor Mrna

A tumor mRNA-triggered nanocarrier was established for multimodal cancer cell imaging and therapy based on the gold nanoparticles functionalized with molecular beacons.

Target Delivery and Cell Imaging Using Hyaluronic Acid-Functionalized Graphene Quantum Dots

2013 ◽  
Vol 10 (10) ◽  
pp. 3736-3744 ◽  
Author(s):  
Abdullah-Al-Nahain ◽  
Jung-Eun Lee ◽  
Insik In ◽  
Haeshin Lee ◽  
Kang Dae Lee ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Hyaluronic Acid ◽  
Cell Imaging ◽  
Graphene Quantum Dots ◽  
Functionalized Graphene ◽  
Target Delivery

scholarly journals Hyaluronic acid Hydrogels Hybridized with Au-Triptolide Nanoparticle for Intra-articular targeted multi-therapy of Rheumatoid Arthritis

2022 ◽  
Author(s):  
Chenxi Li ◽  
Rui Liu ◽  
Yurong Song ◽  
Dongjie Zhu ◽  
Liuchunyang Yu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Gold Nanoparticles ◽  
Hyaluronic Acid ◽  
Near Infrared ◽  
Mtor Pathway ◽  
Collagen Induced Arthritis ◽  
Hybrid Hydrogels ◽  
Low Dosage

Abstract Triptolide (TP) is a DMARD highly effective in patients with RA. Hyaluronic acid (HA) hydrogels loaded RGD-attached gold nanoparticles containing TP were synthesized to alleviate the toxicity and increase therapeutic specificity. The hydrogels can be applied for targeted photothermal-chemo therapy, and in vivo imaging of RA. Heat was locally generated at the inflammation site after degradation of HA chains due to near-infrared resonance (NIR) irradiation of gold nanoparticles (AuNPs), and TP was released. Administration of the hybrid hydrogels containing low dosage of TP combined with NIR irradiation alleviated arthritic conditions and improved the inflamed joint in collagen-induced arthritis (CIA) mice. In vitro effect of the hydrogel was mediated through decrease of phosphorylation of mTOR and its substrate, p70S6K1, thus inhibiting mTOR pathway.

scholarly journals Ultralong purely organic aqueous phosphorescence supramolecular polymer for targeted tumor cell imaging

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wei-Lei Zhou ◽  
Yong Chen ◽  
Qilin Yu ◽  
Haoyang Zhang ◽  
Zhi-Xue Liu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Quantum Yield ◽  
Tumor Targeting ◽  
Room Temperature ◽  
Cell Imaging ◽  
Linear Array ◽  
Water Soluble ◽  
Supramolecular Polymer ◽  
Room Temperature Phosphorescence ◽  
Multiple Hydrogen Bonds

Abstract Purely organic room-temperature phosphorescence has attracted attention for bioimaging but can be quenched in aqueous systems. Here we report a water-soluble ultralong organic room-temperature phosphorescent supramolecular polymer by combining cucurbit[n]uril (CB[7], CB[8]) and hyaluronic acid (HA) as a tumor-targeting ligand conjugated to a 4-(4-bromophenyl)pyridin-1-ium bromide (BrBP) phosphor. The result shows that CB[7] mediated pseudorotaxane polymer CB[7]/HA–BrBP changes from small spherical aggregates to a linear array, whereas complexation with CB[8] results in biaxial pseudorotaxane polymer CB[8]/HA–BrBP which transforms to relatively large aggregates. Owing to the more stable 1:2 inclusion complex between CB[8] and BrBP and the multiple hydrogen bonds, this supramolecular polymer has ultralong purely organic RTP lifetime in water up to 4.33 ms with a quantum yield of 7.58%. Benefiting from the targeting property of HA, this supramolecular polymer is successfully applied for cancer cell targeted phosphorescence imaging of mitochondria.

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