Immobilization of gold nanoparticles on folate-conjugated dendritic mesoporous silica-coated reduced graphene oxide nanosheets: a new nanoplatform for curcumin pH-controlled and targeted delivery

Soft Matter ◽  
2018 ◽  
Vol 14 (12) ◽  
pp. 2400-2410 ◽  
Author(s):  
Samira Malekmohammadi ◽  
Hassan Hadadzadeh ◽  
Hossein Farrokhpour ◽  
Zahra Amirghofran
Keyword(s):  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Folic Acid ◽  
Mesoporous Silica ◽  
Reduced Graphene Oxide ◽  
Targeted Delivery ◽  
Cell Imaging ◽  
Graphene Oxide Nanosheets ◽  
Reduced Graphene ◽  
Gold Nps

A nanocarrier for curcumin targeted delivery and cell imaging was prepared by immobilization of gold NPs on the folic acid-modified dendritic mesoporous silica-coated reduced graphene oxide nanosheets.

scholarly journals Polydopamine-doped virus-like mesoporous silica coated reduced graphene oxide nanosheets for chemo-photothermal synergetic therapy

2020 ◽  
Vol 35 (1) ◽  
pp. 28-38
Author(s):  
Jieying Liao ◽  
Huicong Zhang ◽  
Xuandong Wang
Keyword(s):  
Graphene Oxide ◽  
Mesoporous Silica ◽  
Reduced Graphene Oxide ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Graphene Oxide Nanosheets ◽  
Stratification Method ◽  
Reduced Graphene ◽  
Post Modification

Multifunctional nanocarriers have been widely accepted and utilized for biomedical applications, because of their structural regularity, convenient post-modification and controllable structure and morphology. Herein, we reported polydopamine-doped virus-like mesoporous silica coated reduced graphene oxide nanosheets (rGO@PVMSNs) nanocomposites by a facile oil–water biphase stratification method. The synthesized rGO@PVMSNs nanocomposites performed excellent biocompatibility and photothermal performance. They could be employed as photoacoustic imaging contrast in vivo. Furthermore, the rGO@PVMSNs nanocarriers were used for loading the antitumor drug doxorubicin (DOX), the rGO@PVMSNs@DOX nanocomposites were also demonstrated to be with high inhibition of HepG2 cancer cells, especially with the help of near-infrared irradiation, which were more efficient than single chemotherapy or photothermal therapy. The rGO@PVMSNs@DOX nanocomposites of this work could be used as photoacoustic imaging and chemo-photothermal synergetic therapy agents, which show a new perspective for clinical tumor diagnosis and therapy.

scholarly journals Novel Composite Electrode of the Reduced Graphene Oxide Nanosheets with Gold Nanoparticles Modified by Glucose Oxidase for Electrochemical Reactions

Catalysts ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 764 ◽  
Author(s):  
Dong ◽  
Yu ◽  
Liu ◽  
Liu ◽  
Shao ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Glucose Oxidase ◽  
Reduced Graphene Oxide ◽  
Direct Electron Transfer ◽  
Cyclic Voltammograms ◽  
Graphene Oxide Nanosheets ◽  
X Ray ◽  
Reduced Graphene

Graphene-based composites have been widely explored for electrode and electrocatalyst materials for electrochemical energy systems. In this paper, a novel composite material of the reduced graphene oxide nanosheets (rGON) with gold nanoparticles (NPs) (rGON-AuNP) is synthesized, and its morphology, structure, and composition are characterized by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX), Fourier transform infrared spectroscopic (FTIR), Raman, and UV-Vis techniques. To confirm this material’s electrochemical activity, a glucose oxidase (GOD) is chosen as the target reagent to modify the rGON-AuNP layer to form GOD/rGON-AuNP/glassy carbon (GC) electrode. Two pairs of distinguishable redox peaks, corresponding to the redox processes of two different conformational GOD on AuNP, are observed on the cyclic voltammograms of GOD/rGON-AuNP/GC electrode. Both cyclic voltammetry and electrochemical impedance spectroscopy are employed to study the mechanism of direct electron transfer from GOD to GC electrode on the rGON-AuNP layer. In addition, this GOD/rGON-AuNP/GC electrode shows catalytic activity toward glucose oxidation reaction.

Polyaptamer DNA nanothread-anchored, reduced graphene oxide nanosheets for targeted delivery

Biomaterials ◽  
2015 ◽  
Vol 48 ◽  
pp. 129-136 ◽  
Author(s):  
Mi-Gyeong Kim ◽  
Joo Yeon Park ◽  
Wenjun Miao ◽  
Jaiwoo Lee ◽  
Yu-Kyoung Oh
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Targeted Delivery ◽  
Graphene Oxide Nanosheets ◽  
Reduced Graphene
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