Inammation in Rheumatic and Arthritic Diseases: Role of Dietary Phytochemicals

2016 ◽  
pp. 128-157
Keyword(s):  
Dietary Phytochemicals

scholarly journals Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View

2020 ◽  
Vol 2020 ◽  
pp. 1-20 ◽  
Author(s):  
Klara Komici ◽  
Valeria Conti ◽  
Sergio Davinelli ◽  
Leonardo Bencivenga ◽  
Giuseppe Rengo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Point Of View ◽  
World Population ◽  
Efficacy And Safety ◽  
Innovative Strategy ◽  
Dietary Phytochemicals ◽  
Clinical Models ◽  
Cardioprotective Effects ◽  
Therapeutic Tools

Dietary phytochemicals are considered an innovative strategy that helps to reduce cardiovascular risk factors. Some phytochemicals have been shown to play a beneficial role in lipid metabolism, to improve endothelial function and to modify oxidative stress pathways in experimental and clinical models of cardiovascular impairment. Importantly, investigation on phytochemical effect on cardiac remodeling appears to be promising. Nowadays, drug therapy and implantation of devices have demonstrated to ameliorate survival. Of interest, sex-gender seems to influence the response to HF canonical therapies. In fact, starting by the evidence of the feminization of world population and the scarce efficacy and safety of the traditional drugs in women, the search of alternative therapeutic tools has become mandatory. The aim of this review is to summarize the possible role of dietary phytochemicals in HF therapy and the evidence of a different sex-gender-oriented response.

Dietary Phytochemicals: As a Natural Source of Antioxidants

2021 ◽  
Author(s):  
Manju Singh Makhaik ◽  
Arvind K. Shakya ◽  
Raosaheb Kale
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Free Radical ◽  
Brain Dysfunction ◽  
Cellular Inflammation ◽  
Hepatic Diseases ◽  
Dietary Phytochemicals ◽  
Free Radical Formation ◽  
Prevention And Cure

Since time immemorial, plants are used as the source of food and medicine. It can be traced back to the start of humanity. Bringing plant-based food, such as fruits, vegetables, and whole grains, rich in phytochemicals, with beneficial nutrients, opens the door for healthy living. The health benefits are partly attributed to the compounds which possess antioxidants. Several epidemiological observations have shown an opposite relationship between consumption of plant-based foods, rich in phytochemicals, and many diseases including cancer. The majority of the ailments are related to oxidative stress induced by free radicals. Free radicals are extremely unstable with a very short half-life, highly reactive molecule which leads to oxidative damage to macromolecules such as proteins, DNA, and lipids. Free radical induced cellular inflammation appears to be a major contributing factor to cause aging, and degenerative diseases such as cancer, cardiovascular diseases, diabetes, hepatic diseases, renal ailments, and brain dysfunction. Free radicals have been caught up in the pathogenesis of several diseases. Providentially, free radical formation is controlled naturally by phytochemicals, through their antioxidant potential which plays a key role in preventing many diseases including cancer by suppressing oxidative stress-induced DNA damage. Keeping these facts in mind, an attempt has been made to highlight the oxidative stress, enzymatic and non-enzymatic antioxidant, dietary phytochemicals and their role of in disease prevention and cure.

Chemopreventive Role of Dietary Phytochemicals in Colorectal Cancer

2018 ◽  
pp. 69-121 ◽  
Author(s):  
Megha Bansal ◽  
Neha Singh ◽  
Saurabh Pal ◽  
Indra Dev ◽  
Kausar Mahmood Ansari
Keyword(s):  
Colorectal Cancer ◽  
Dietary Phytochemicals

scholarly journals A Role of Stress Sensor Nrf2 in Stimulating Thermogenesis and Energy Expenditure

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1196
Author(s):  
Seo-Hyuk Chang ◽  
Jeong-Soo Lee ◽  
Ui Jeong Yun ◽  
Kye Won Park
Keyword(s):  
Energy Expenditure ◽  
Metabolic Diseases ◽  
Atp Synthesis ◽  
Related Factor ◽  
Nrf2 Activation ◽  
Dietary Phytochemicals ◽  
Potential Applications ◽  
Thermogenic Adipocytes ◽  
Endogenous Metabolites

During chronic cold stress, thermogenic adipocytes generate heat through uncoupling of mitochondrial respiration from ATP synthesis. Recent discovery of various dietary phytochemicals, endogenous metabolites, synthetic compounds, and their molecular targets for stimulating thermogenesis has provided promising strategies to treat or prevent obesity and its associated metabolic diseases. Nuclear factor E2 p45-related factor 2 (Nrf2) is a stress response protein that plays an important role in obesity and metabolisms. However, both Nrf2 activation and Nrf2 inhibition can suppress obesity and metabolic diseases. Here, we summarized and discussed conflicting findings of Nrf2 activities accounting for part of the variance in thermogenesis and energy metabolism. We also discussed the utility of Nrf2-activating mechanisms for their potential applications in stimulating energy expenditure to prevent obesity and improve metabolic deficits.

Pleiotropic Role of Dietary Phytochemicals in Cancer: Emerging Perspectives for Combinational Therapy

2015 ◽  
Vol 67 (7) ◽  
pp. 1021-1048 ◽  
Author(s):  
Sivanantham Banudevi ◽  
Sethuraman Swaminathan ◽  
Krishnan Uma Maheswari
Keyword(s):  
Combinational Therapy ◽  
Dietary Phytochemicals

scholarly journals Role of dietary phytochemicals in modulation of miRNA expression: Natural swords combating breast cancer

2018 ◽  
Vol 11 (9) ◽  
pp. 501 ◽  
Author(s):  
Javed Iqbal ◽  
Tariq Mahmood ◽  
BanzeerAhsan Abbasi ◽  
AliTalha Khalil ◽  
Barkat Ali ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mirna Expression ◽  
Dietary Phytochemicals
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