Nutrigenomics: future for sustenance

Nutrigenomics deals with the effect of foods and food constituents on gene expression. It is a new concept in disease prevention and cure. Nutrigenomics conveys how nutrients influence our body to express genes, whereas nutrigenetics refers to how our body responds to nutrients. The various bioactive food components can alter the gene expression mechanisms. But our actual knowledge is so insufficient that the only use of such information may help to satisfy our imagination. If science could arrive at some more precise facts, that would have vast applications in medicine.

The biotherapics Influenzinum and Oscilococcinum in the treatment of influenza virus flu

Introduction: The influenza virus flu is a widespread illness which is responsible for hundreds of thousands of deaths annually. About 20% of children and 5% of adults are infected with this virus every year. The disease is highly contagious and its transmission occurs by saliva particles of the infected person, expelled by breathing, talking and coughing [1]. Flu pandemics are generally caused by the appearance of a new subtype of the virus in humans, which occurs as a result of the existing flu in animal species transmitted to humans [2]. Despite the fact there are antiviral drugs, the virus develops mutations, creating resistance to these drugs in few days. Thus, the development of new therapies, including homeopathy, that can prevent and/or treat this disease becomes increasingly necessary. In this scenario, biotherapics appear as drugs that are made from biological products, such as secretions, tissues, organs whose compounding follows the homeopathic pharmacopeia. Objective: This study is a literature review on the treatment of flu with biotherapics used in clinical medicine, namely Influenzinum and Oscilococcinum. Method: Studies on the prescription of biotherapics for the prevention and cure of the flu as well as literature about the history and evolution of Homeopathy were reviewed in the present work. Influenzinum is a biotherapic made from the influenza vaccine from Pasteur Laboratory, while Oscillococcinum is obtained from the lysate of the liver and heart of the goose Anas barbaries. Results: Preliminary results showed that both medicines are widely used in clinical medicine. Influenzinum 9CH is prescribed for flu prevention and treatment, while Oscilococcinum is more used to reduce the severe symptoms in patients who already have the flu. Conclusion: Based on these results, it is possible to say that Influenzinum has a very important role in the prevention and cure of the influenza and Oscilococcinnum is useful in the relief of the symptoms caused by this disease

A critical Review of Dhoopan Karma in Ayurveda and Dhoopana of an Ayurvedic Herbomineral formulation Yavasarshapadi churna in context of Sterilization.

Dhoopana Karma is classical remedy mentioned in various Ayurvedic scriptures to maintain disease free and hygienic environment in the world. As per Ayurvedic scriptures Dhoopana is indicated for Rakshoghna Karma which means killing of disease producing microorganisms. Hence, it plays key role in prevention and cure of various infectious diseases.A similar process called fumigation is one of best and fastest method to maintain asepsis, antisepsis in wards and operation theatres of hospitals.Additionally, this study comprises critical literary review of herbomineral formulation named Yavasarshapadi Choorna which is indicated in form of incense for Dhoopana karma. It is indicated in Ayurvedic scripture Charaka Samhita in chapter Jatisutriya Sharir Adhyaya of Sharir Sthana. It was reviewed in context of sterilization activity to maintain asepsis and antisepsis. Specifically, it is indicated for fumigation of cloths and belongings of post-natal period of Women and that of the New born, Drug preparation room, New born care room, Surgical Procedure room modern surgery, traditional operation theatre sterilization was done by formalin gas fumigation over many decades which is found to have carcinogenic effect over human lives. Ayurvedic modality named Dhoopana was undertaken in current study as it is a safe and healthy alternative for sterilization.It overcomes harmful effects caused by modern sterilization method i.e. Formalin gas fumigation which is need of an hour. The Analytical study of antimicrobial and antifungal effect of various Ayurvedic Dhoopana Dravyas is the need of the hour along with preclinical and clinical study to verify Sterilization activity of various Ayurvedic Dhoopana Dravyas.

Anti-COVID-19 Biomedicines - A Layout Proposal for Production, Storage and Transportation

Background: Modulation of non-specific immunity and other related activities of succulent parts of effective medicinal plants can prevent viral infections like COVID-19 through their dietary intake. Objective: The succulent parts of the medicinal plants with immunomodulation, anti-oxidation, anti-viral, anti-inflammatory, etc. power can be used orally in the capsular form to prevent as well as to reduce the severity of symptoms of COVID-19. Methods: A proposal is displayed with a detailed description of related steps like the selection of medicinal plant parts consulting related reports, collection of biomedicines, validation of efficacy, dosing, encapsulation, storage, and transportation, etc. Results: The succulent bio-medicines against COVID-19 can be developed and marketed following only some adoptive research. Conclusion: Succulent bio-medicines can be prepared and marketed for the prevention and cure of different infectious and non-infectious diseases.

PEMANFAATAN OBAT TRADISIONAL PENANGKAL PENULARAN COVID-19

In this time of the rampant Covid-19 pandemic, all recommended treatments and vaccines do not guarantee that you will be protected from the Covid-19 virus. Moreover, currently the positive rate of Covid-19 is very high in Indonesia so that people really need traditional medicines in dealing with the Covid-19 pandemic. Several researchers in Indonesia suggest traditional medicines that have been tested in the laboratory as an alternative in handling Covid-19, apart from being easy to find and cheap, traditional medicines are also believed to increase the body's immunity. Online media in Indonesia are also not a few who report about traditional medicines that are effective in handling Covid-19, social media is also a place for all information on traditional medicines. This article was created with the aim of making people aware of the benefits of good traditional medicines to increase body immunity. In this article, using normative legal research methods. Soerjono Soekanto and Sri Mamudji (2007) explains that in normative legal research, the basic data used are library materials which in research science are classified as secondary data. The results of this study show that: (1) the role of traditional medicine is very helpful for first aid during the Covid-19 pandemic; (2) factors supporting the body's immunity during the Covid-19 pandemic; (3) disease prevention and cure of minor ailments. Based on the results of this study, it can be concluded that traditional medicines such as garlic, ginger, honey, red ginger, turmeric, bitter, and several other herbal medicines can be focused on extraction to produce active compounds as Covid-19 immunomodulators.Masa pandemi Covid-19 yang sedang marak ini, sehingga segala pengobatan dan vaksin yang dianjurkan tidak menjamin akan terhindar dari virus Covid-19. Terlebih, sekarang ini tingkat angka positif Covid-19 sangat tinggi di Indonesia sehingga masyarakat sangat membutuhkan obat-obat tradisional dalam menghadapi pandemi Covid-19. Beberapa peneliti di Indonesia menyarankan obat-obat tradisional yang sudah teruji di laboratorium sebagai alternatif dalam penanganan Covid-19,alasannya selain karena mudah ditemukan dan murah, obat-obat tradisional juga dipercaya dapat meningkatkan imunitas tubuh. Media online di Indonesia juga tidak sedikit yang memberitakan tentang obat-obat tradisional yang ampuh dalam penanganan Covid-19, sosial media juga menjadi wadah untuk segala informasi obat-obat tradisional. Artikel ini dibuat dengan tujuan agar masyarakat mengetahui manfaat dari obat-obat tradisional yang bagus untuk meningkatkan imunitas tubuh. Dalam artikel ini, menggunakan metode penelitian hukum normatif yang berfokus pada data sekunder pengolahan dan analisis data dilakukan secara kualitatif dengan menggunakan logika deduktif .Obat tradisional sangat membantu untuk pertolongan pertama di masa pandemi Covid-19, faktor penunjang imunitas tubuh di masa pandemi Covid-19, pencegahan penyakit, dan penyembuhan penyakit yang ringan. Obat-obat tradisional seperti, bawang putih, temulawak, madu, jahe merah, kunyit, sambiloto, dan beberapa obat herbal lainnya dapat difokuskan untuk diekstraksi guna menghasilkan senyawa aktif sebagai pengatur sistem kekebalan tubuh Covid-19.

The Role of Prophetic Food in The Prevention and Cure of Chronic Diseases: A Review of Literature

Islam is the way of life. It exists in each and every moment and action of an individual. Muhammad (PBUH) is the finest of all examples in every aspect. In Islam, halal and tayyib food is important for individual prosperity and wellbeing. This is because food intake has the potential to influence human growth in terms of akhlaq, morality, and psychology. This paper studies the significance of consuming prophetic food as a healthy diet. A few highlighted issues will be discussed, such as the increasing rate of chronic diseases that have become high causes of death, as well as unhealthy eating habits amongst Malaysians regardless of age and background. Undoubtedly, the ability of nutrition and functional food from the practice of the Prophet Muhammad (PBUH) has proven to be one of the best ways to prevent and cure most chronic diseases with the low side effects. This paper discusses how prophetic food helps in resolving global health issues and combating chronic disease. These issues are extracted from the literature by thoroughly studying published work and research. Finding shows that there is a presence of high medicinal values in prophetic food and evidence provided in The Holy Quran and Hadiths is proven scientifically through available research and citations. The paper provides valuable insights to the Prophetic food consumption among Muslim consumers and the halal industry.

EXPLORING THE POSSIBILITIES AND CHALLENGES IN IMMUNOMODULATORY STRATEGIES IN KAUMARABHRITYA WITH SPECIAL REFERENCE TO YUKTIKRITA BALA

Immunization has been one of the biggest success stories of modern medicine. The WHO estimates that at least 10 million deaths were prevented between 2010 and 2015.Ayurveda upholds the unique principles of strengthening innate resistance of an individual in prevention and cure of diseases which is inculcated from the time of conception.The bala or vyadhikshamatva is the functional aspect of ojus.Vyadhi utpadak pratibandhakatva and Vyadhibala virodhitva which are the two aspects of vyadhikshamatva are determined and controlled by the state of Ojus.The immunomodulation is done through the medium of medicines at proper age, dose and state of body along with proper diet,regimen and state of mind. The study explores the immuno modulation strategies in children through a literature survey through the Brhat trayee and kaumarabhritya classics like Kashyapa samhitha,Arogya kalpadruma along with relevant online articles..”Prakara yoga” will be elaborated for its immunomodulatory action.An experience survey among ayurveda experts for the use of methodologies for use and practicality of these strategies also is included. Key words : immunomodulation,vyadhikshamatva,ayurveda.