Concurrent Testing

2006 ◽  
pp. 133-145
Keyword(s):  
Concurrent Testing

scholarly journals Risk of Coinfection withChlamydia trachomatisandNeisseria Gonorrhoeaein Nova Scotia

2010 ◽  
Vol 21 (2) ◽  
pp. e84-e86 ◽  
Author(s):  
Kevin R Forward
Keyword(s):  
Nova Scotia ◽  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Treatment Decisions ◽  
Empirical Treatment ◽  
Prevalence Rates ◽  
Accession Number ◽  
Males And Females ◽  
Concurrent Testing

BACKGROUND: The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.OBJECTIVE: To determine the frequency ofC trachomatisandN gonorrhoeaecoinfections by evaluating the results of testing in 2007 and 2008 to better inform testing and treatment decisions.METHODS: Specimens from the same patient submitted on the same day served as the basis for the present study. The age, sex and the source of the specimen were also linked to the accession number. Infection and coinfection rates were analyzed in both males and females.RESULTS: Concurrent testing was performed on 41,567 female specimens and 1827 male specimens, of which, 1495 female samples (3.6%) tested positive forC trachomatisinfection and 88 (0.2%) tested positive forN gonorrhoeaeinfections. Only 31 females were coinfected; however, for those between 11 and 25 years of age, 25 of 61 females (40.1%) withN gonorrhoeaeinfection also tested positive forC trachomatisinfection; conversely, 25 of 1248 females (2.0%) withC trachomatisinfection also tested positive forN gonorrhoeaeinfection. For males, 213 (11.7%) tested positive forC trachomatisinfection,and 59 (3.2%) tested positive forN gonorrhoeaeinfection. In 30 males withN gonorrhoeaebetween 11 and 25 years of age, and 149 males withC trachomatis,eight coinfections were observed (26.7% and 5.3%, respectively). Of those older than 25 years of age, only five of 905 men and six of 19,465 women were coinfected. None of the 10,935 women who were 30 years of age or older had coinfections.CONCLUSION: TheN gonorrhoeaecoinfection rate in males withC trachomatismay justify empirical antimicrobials; however, in females, the proportion of coinfected may not justify empirical treatment forN gonorrhoeaeinfection when theC trachomatistest is positive andN gonorrhoeaetesting has not been performed.

Concurrent testing of digital microfluidics-based biochips

2006 ◽  
Vol 11 (2) ◽  
pp. 442-464 ◽  
Author(s):  
Fei Su ◽  
Sule Ozev ◽  
Krishnendu Chakrabarty
Keyword(s):  
Digital Microfluidics ◽  
Concurrent Testing

Gonorrhoea testing and positivity in non-remote Aboriginal Community Controlled Health Services

Sexual Health ◽  
2017 ◽  
Vol 14 (4) ◽  
pp. 320 ◽  
Author(s):  
Mary Ellen Harrod ◽  
Sophia Couzos ◽  
James Ward ◽  
Mark Saunders ◽  
Basil Donovan ◽  
...  
Keyword(s):  
Health Services ◽  
Torres Strait Islander ◽  
Clinical Encounter ◽  
Current Approach ◽  
Research Network ◽  
Torres Strait Islander People ◽  
Remote Communities ◽  
Aboriginal Community ◽  
Torres Strait ◽  
Concurrent Testing

Background Gonorrhoea occurs at high levels in young Aboriginal and Torres Strait Islander people living in remote communities, but there are limited data on urban and regional settings. An analysis was undertaken of gonorrhoea testing and positivity at four non-remote Aboriginal Community Controlled Health Services participating in a collaborative research network. Methods: This was a retrospective analysis of clinical encounter data derived from electronic medical records at participating services. Data were extracted using the GRHANITE program for all patients aged 15–54 years from 2009 to 2013. Demographic characteristics and testing and positivity for gonorrhoea were calculated for each year. Results: A total of 2971 patients (2571 Aboriginal and/or Torres Strait Islander) were tested for gonorrhoea during the study period. Among Aboriginal and/or Torres Strait Islander patients, 40 (1.6%) tested positive. Gonorrhoea positivity was associated with clinic location (higher in the regional clinic) and having had a positive chlamydia test. By year, the proportion of patients aged 15–29 years tested for gonorrhoea increased in both men (7.4% in 2009 to 15.9% in 2013) and women (14.8% in 2009 to 25.3% in 2013). Concurrent testing for chlamydia was performed on 86.3% of testing occasions, increasing from 75% in 2009 to 92% in 2013. Factors related to concurrent testing were sex and year of test. Conclusions: The prevalence of gonorrhoea among young Aboriginal and/or Torres Strait Islander people in non-remote settings suggests that the current approach of duplex testing for chlamydia and gonorrhoea simultaneously is justified, particularly for women.

Concurrent testing of processes

1995 ◽  
Vol 32 (6) ◽  
pp. 509-543 ◽  
Author(s):  
M. Hennessy
Keyword(s):  
Concurrent Testing

scholarly journals Blastomyces dermatitidis Antigen Detection by Quantitative Enzyme Immunoassay

2011 ◽  
Vol 19 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Patricia Connolly ◽  
Chadi A. Hage ◽  
J. Ryan Bariola ◽  
Eric Bensadoun ◽  
Mark Rodgers ◽  
...  
Keyword(s):  
Enzyme Immunoassay ◽  
Healthy Subjects ◽  
Antigen Detection ◽  
Antigen Level ◽  
Antigen Concentration ◽  
Content Type ◽  
Antigen Assay ◽  
Concurrent Testing ◽  
Urine And Serum ◽  
Urine Specimens

ABSTRACTThe second-generation MVistaBlastomycesantigen enzyme immunoassay was not quantitative; therefore, specimens obtained previously were tested in the same assay as new specimens to assess the change in antigen levels. Furthermore, the sensitivity in serum had not been fully evaluated. The purpose of this study was to evaluate a quantitativeBlastomycesantigen assay and detection of antigen in serum. Calibrators containing known concentrations ofBlastomycesgalactomannan were used to quantify antigen in urine and serum from patients with proven blastomycosis and from controls. Paired current and previously obtained urine specimens were tested to determine if quantification eliminated the need for concurrent testing to assess change in antigen. Pretreatment of serum with EDTA at 104°C was evaluated to determine if dissociation of immune complexes improved detection of antigenemia. Antigenuria was detected in 89.9% of patients with culture- or histopathology-proven blastomycosis. Specificity was 99.0% in patients with nonfungal infections and healthy subjects, but cross-reactions occurred in 95.6% of patients with histoplasmosis. Change in antigen level categorized as increase, no change, or decrease based on antigen units determined in the same assay agreed closely with the category of change in ng/ml determined from different assays. Pretreatment increased the sensitivity of detection of antigenemia from 35.7% to 57.1%. Quantification eliminated the need for concurrent testing of current and previously obtained specimens for assessment of changes in antigen concentration. Pretreatment increased the sensitivity for detection of antigenemia. Differentiation of histoplasmosis and blastomycosis is not possible by antigen detection.

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