Month of Birth and Schizophrenia in Korea

1994 ◽  
Vol 164 (6) ◽  
pp. 829-831 ◽  
Author(s):  
Chul-Eung Kim ◽  
Young-Sook Lee ◽  
Young-Hee Lim ◽  
In-Young Noh ◽  
S. H. Park
Keyword(s):  
Family History ◽  
Season Of Birth ◽  
Month Of Birth ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
Age And Sex

This study investigates whether there is any difference in the month of birth between people with schizophrenia and controls in Korea. When 1606 patients with schizophrenia were compared with 4582 age- and sex-matched controls, there was no statistically significant difference in the month of birth, the season of birth of schizophrenic patients was not related to sex, family history or handedness.

Month of birth in deficit and non-deficit schizophrenic patients

1999 ◽  
Vol 14 (6) ◽  
pp. 349-351 ◽  
Author(s):  
S. Dollfus ◽  
P. Brazo ◽  
S. Langlois ◽  
R. Gourevitch ◽  
D. Dassa ◽  
...  
Keyword(s):  
Risk Factor ◽  
Season Of Birth ◽  
Month Of Birth ◽  
Deficit Syndrome ◽  
Deficit Schizophrenia ◽  
Significant Difference ◽  
Schizophrenic Patients

SummaryIn order to test the hypothesis that an excess of summer births is a risk factor for deficit syndrome, the month of birth was studied in 53 deficit schizophrenic patients compared to 158 non-deficit patients. No significant difference in terms of month of birth or season of birth was observed between deficit and non-deficit patients, suggesting that summer births might not be a risk factor for deficit schizophrenia.

Early Cortical Tactile-Evoked Potentials, Laterality and Schizophrenia

1991 ◽  
Vol 158 (4) ◽  
pp. 529-533 ◽  
Author(s):  
Jane E. Allen ◽  
Alec Jenner ◽  
John C. Stevens
Keyword(s):  
Evoked Potentials ◽  
Tactile Stimulus ◽  
Index Finger ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
Age And Sex

No significant difference in the lateralisation of tactile-evoked potentials was found when a tactile stimulus was applied to the index finger of 14 schizophrenic patients and 14 age- and sex-matched controls. The early tactile responses, recorded from contralateral and ipsilateral parietal scalp electrodes, were compared. Our results differ from previously reported results.

scholarly journals Prolonged Methamphetamine-Induced Psychosis: Difference With Schizophrenia

2019 ◽  
Author(s):  
Hamid Reza Ahmadkhaniha ◽  
Kaveh Alavi ◽  
Fatemeh Hadi
Keyword(s):  
Family History ◽  
Obstetric Complications ◽  
Medical Sciences ◽  
Neurological Soft Signs ◽  
Demographic Questionnaire ◽  
Significant Difference ◽  
Other Substances ◽  
Schizophrenic Patients ◽  
History Of ◽  
Close Relatives

The main objective of the present study was to compare the distribution of underlying factors such as neurological soft signs, obstetric complications, and family history of psychiatric disorders between two groups of schizophrenic patients and patients with prolonged methamphetamine-induced psychosis. In a case-control study, 30 patients with prolonged methamphetamine-induced psychosis and 30 patients with schizophrenia were selected. Data were collected through a demographic questionnaire, the Buchanan and Heinrichs’ Neurological Evaluation Scale (NES), the Lewis-Murray’s Obstetric Complications Scale (LMOCS), and the Weissman’s Family History Screen (FHS). Mean scores of the neurological soft signs (±SD) in the two groups of schizophrenic patients and patients with prolonged methamphetamine-induced psychosis were 15.7±8.7 and 11.7±6.2, respectively (P=0.040), and a significant difference was observed in the sensory integration between the two groups (P=0.022). Obstetric complications revealed similar distributions in the two groups. Patients with prolonged methamphetamine-induced psychosis reported higher prevalence of alcohol and other substances use disorders (P=0.003 and P=0.001, respectively) in their close relatives; however, the distributions of other disorders were not statistically different between the two groups’ close relatives. Similarities and differences in certain aspects were observed between the two groups, suggesting susceptibility for psychosis in patients with prolonged methamphetamine-induced psychosis; yet we found diversities that distinguish the two disorders. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(4):235-243

The Nithsdale Schizophrenia Surveys X: Obstetric Complications, Family History and Abnormal Movements

1992 ◽  
Vol 160 (6) ◽  
pp. 799-805 ◽  
Author(s):  
Robin G. McCreadie ◽  
David J. Hall ◽  
Ian J. Berry ◽  
Lesley J. Robertson ◽  
James I. Ewing ◽  
...  
Keyword(s):  
Family History ◽  
Tardive Dyskinesia ◽  
Psychiatric Illness ◽  
Obstetric Complications ◽  
Degree Relative ◽  
Drug Induced ◽  
Abnormal Movements ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
History Of

Obstetric histories of 54 schizophrenic patients and 114 siblings were obtained from their mothers and scored using the Obstetric Complications Scale. There was no statistically significant difference in the proportion of schizophrenic patients (35%) and siblings (29%) who had at least one definite obstetric complication. There was no evidence that schizophrenic patients with a history of obstetric complications were less likely to have a first-degree relative with a history of psychiatric illness leading to in-patient care. Schizophrenic patients with a history of obstetric complications were more likely to have drug-induced Parkinsonism. There was a trend for tardive dyskinesia to be more common in those schizophrenic patients with no obstetric complications but a family history of schizophrenia.

Minimal brain damage and seasonality of birth in schizophrenic disorders

1992 ◽  
Vol 7 (2) ◽  
pp. 91-92 ◽  
Author(s):  
V di Michele ◽  
S de Cataldo ◽  
A Rossi ◽  
M Casacchia
Keyword(s):  
Brain Damage ◽  
Season Of Birth ◽  
Neurological Soft Signs ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
Seasonality Of Birth

SummaryA minimal brain damage examination was carried out in 73 schizophrenic patients divided into three groups according to their season of birth. Results showed no statistically significant difference among groups in the prevalence of neurological soft signs.

Season of Birth in Schizophrenia

1991 ◽  
Vol 158 (6) ◽  
pp. 764-769 ◽  
Author(s):  
Eadbhard O'Callaghan ◽  
Tessa Gibson ◽  
Hubert A. Colohan ◽  
David Walshe ◽  
Peter Buckley ◽  
...  
Keyword(s):  
Family History ◽  
Psychiatric Disorder ◽  
Environmental Factor ◽  
Normal Population ◽  
Season Of Birth ◽  
Significant Excess ◽  
Degree Relative ◽  
Schizophrenic Patients ◽  
History Of ◽  
Population Controls

Although it is well recognised that schizophrenic patients are more often born in winter, the significance of this finding remains obscure. Data relating to season of birth and family history were analysed for 561 patients with an ICD–9 diagnosis of schizophrenia. Patients with no family history of any psychiatric disorder group were significantly more likely to be born in winter than patients with a first-degree relative affected by schizophrenia. In comparison with normal population controls, only those without a family history exhibited a significant excess of winter births, suggesting an environmental factor of greater aetiological significance in these patients.

Risk Factors in Schizophrenia

1988 ◽  
Vol 152 (4) ◽  
pp. 460-465 ◽  
Author(s):  
Miron Baron ◽  
Rhoda Gruen
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Age At Onset ◽  
Familial Risk ◽  
Season Of Birth ◽  
Birth Season ◽  
Increased Risk ◽  
Schizophrenic Patients ◽  
History Of ◽  
Spectrum Disorders

The association between the familial risk for schizophrenia and season of birth was studied in 88 schizophrenic patients. An increased risk for schizophrenia and ‘spectrum’ disorders was demonstrated among the first-degree relatives of winter and spring-born schizophrenic patients. However, patients with a family history of schizophrenia and ‘spectrum’ disorders did not differ from patients with no family history with respect to season of birth. Season of birth was unrelated to the sex of the patient, birth order, age at onset, or clinical subtypes (paranoid vs non-paranoid, as defined by the RDC, and ‘narrow’ vs ‘broad’, as defined by Taylor & Abrams' 1975 criteria). The morbid-risk data support a ‘stress-diathesis' hypothesis whereby environmental factors (in this case a seasonally varying viral insult may be implicated) interact with genetic vulnerability to increase the risk for schizophrenia.

scholarly journals 1641. A Comparative Analysis Of Lymph Node Tuberculosis Between Children And Adults

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S810-S810
Author(s):  
Fatma Hammami ◽  
Makram Koubaa ◽  
Amal Chakroun ◽  
Khaoula Rekik ◽  
Fatma Smaoui ◽  
...  
Keyword(s):  
Lymph Node ◽  
Family History ◽  
Extrapulmonary Tuberculosis ◽  
Diagnostic Delay ◽  
Disease Evolution ◽  
Evolutionary Features ◽  
Significant Difference ◽  
History Of ◽  
Adults And Children ◽  
Lymph Node Tuberculosis

Abstract Background Lymph node tuberculosis (LNTB) represents the most common site of extrapulmonary tuberculosis. Among children, due to non-specific clinical features, the diagnosis is often delayed. We aimed to compare the clinical, therapeutic and evolutionary features of LNTB between adults and children. Methods We conducted a retrospective study including patients hospitalized for LNTB in the infectious diseases and pediatric department between 1993 and 2018. Children aged ≤18 years were included. Results Overall, we encountered 231 cases of LNTB. There were 40 children (17.3%) with a mean age of 11±4 years and 191 adults (82.7%) with a mean age of 42±16 years. As to gender, females were more affected (adults: 67% vs children: 70%), with no significant difference (p >0.05). A family history of tuberculosis was significantly more frequent among children (20% vs 6.3%; p=0.01). Raw milk consumption (38.2% vs 30%; p >0.05) and close contact with animals (29.8% vs 35%; p >0.05) were noted among both adults and children. Fever (53.4% vs 32.5%; p=0.01), night sweats (35.8% vs 10%; p=0.001), loss of appetite (38.2% vs 17.5%; p=0.01) and weight loss (35.1% vs 15%; p=0.01) were significantly more frequent among adults. Tuberculin skin test was positive in 75.8% of the cases among adults and in 86.2% of the cases among children (p >0.05). Multifocal tuberculosis was significantly more frequent among adults (23.8% vs 5.7%; p=0.01). Antitubercular therapy was prescribed for a mean duration of 10±4 months among adults and for 9±3 months among children, with no significant difference (p >0.05). Side effects of antitubercular drugs were more frequent among adults (33% vs 10.3%), with a significant difference (p=0.004). Comparison of the disease evolution showed no significant difference between adults and children, regarding recovery (94.8% vs 90%), relapse (5.2% vs 5%) and death (0.5% vs 2.5%). Conclusion The clinical presentation of LNTB among children was less common and misleading. A family history of tuberculosis and a high index of suspicion might shorten the diagnostic delay. Disclosures All Authors: No reported disclosures

scholarly journals Correlation between ZBRK1/ZNF350 gene polymorphism and breast cancer

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Jun Wu ◽  
Alibiati Eni ◽  
Eliar Roussuri ◽  
Binlin Ma
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Gene Polymorphism ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Control Groups ◽  
Wild Genotype ◽  
Mutant Genotype ◽  
Synonymous Mutations ◽  
Significant Difference

Abstract Background This study is to explore the relationship between the ZBRK1/ZNF350 (Zinc finger and BRCA1-interacting protein with KRAB domain-1; also known as zinc-finger protein 350) gene polymorphism and early-onset breast cancer. Methods The ZBRK1/ZNF350 gene exon detection analysis was performed with the direct sequencing and Snapshot methods in 80 cases of breast cancer (aged ≤ 40 years old) and 240 healthy subjects (aged ≤ 40 years old). Results Totally 9 sequence variants were detected, including 5 missense mutations and 4 synonymous mutations, located at EXON3, EXON4 and EXON5, respectively. The rs4987241 and rs3764538 variants were published for the first time, while the remaining variants had been reported before. There were significant differences in the frequency distribution of family history between the breast cancer and control groups. Moreover, there were significant differences in the CT genotype frequency at the rs138898320 locus between the breast cancer and healthy control groups. Compared with the carriers of CC wild genotype at rs138898320, the risk of breast cancer was reduced by 88.3% in the CT mutant genotype carriers, with significant difference. In the stratification with no family history, compared with the carriers of CC wild genotype at rs138898320, significant differences were observed for the CT mutant genotype carriers. In the stratification with family history, there was no significant difference in the variation of rs138898320. Conclusion The rs138898320 CT mutation genotype of ZBRK1/ZNF350 may reduce the risk of breast cancer, and the protecting effect would be increased in the stratification with no family history. Trial registration Not applicable.

Somatosensory Evoked Potentials in Schizophrenia a Lateralisation Study

1990 ◽  
Vol 157 (6) ◽  
pp. 881-887 ◽  
Author(s):  
Paul Furlong ◽  
Paul Barczak ◽  
Gwilym Hayes ◽  
Graham Harding
Keyword(s):  
Index Finger ◽  
Objective Measure ◽  
Control Group ◽  
Temporal Region ◽  
Control Groups ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
Left And Right ◽  
And Control ◽  
Stimulation Of

The SSEPs obtained from 19 schizophrenics defined by RDC, DSM–III and PSE criteria Were compared with those from a control group of healthy volunteers. Previous findings of an abnormal lack of lateralising response in schizophrenic patients were not replicated. No significant difference in either amplitude or morphology between the traces obtained from the two groups were recorded. Ipsilateral and contralateral latencies for stimulation of the left and right index finger showed no significant difference in peak latency for any component between patient and control group. When mean peak-to-peak amplitudes were plotted the contralateral component was always greater in amplitude than the ipsilateral one. An objective measure of the degree of lateralisation, the percentage lateralisation quotient, showed no lateralisation differences between the patient and control groups. A case of myogenic contamination of ipsilateral components was observed calling into doubt findings where no temporal region monitoring has been performed.

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