The Prognosis of Affective Disorders: the Differentiation of Anxiety States from Depressive Illnesses

1972 ◽  
Vol 121 (561) ◽  
pp. 175-181 ◽  
Author(s):  
Kurt Schapira ◽  
Martin Roth ◽  
T. A. Kerr ◽  
Clair Gurney

That a distinction may be made on clinical grounds between anxiety states and depressive illnesses has been affirmed by some authors (Garmany, 1956, 1958; Stenbäck, 1963), and rejected by others (Mapother, 1926; Conrad, 1958; Ey, 1963; Lewis, 1950–1966). This problem is also of interest from a biological point of view in that anxiety neuroses represent in an exaggerated form an emotion that is ‘directly serviceable’ (Cannon, 1928) and one which has potential survival value for the organism. Moreover, analogous conditions can be reproduced experimentally in animals, while no convincing models have so far been described of states akin to depressive illnesses (McKinney and Bunney, 1969).

1972 ◽  
Vol 121 (561) ◽  
pp. 167-174 ◽  
Author(s):  
T. A. Kerr ◽  
Martin Roth ◽  
Kurt Schapira ◽  
Clair Gurney

While detailed and systematic studies have been carried out on the course and outcome of manic-depressive psychoses (Kraepelin, 1921; Rennie, 1942; Poort, 1945; Lundquist, 1945; Astrup et al., 1959; Olsen, 1961; Bratfos and Haug, 1968), depressive illnesses (Lewis, 1936; Kay et al, 1969) and anxiety states (Miles et al., 1951; Eitinger, 1955; Greer and Cawley, 1966), there is little information concerning the prognosis of affective disorders as a whole.


2020 ◽  
Vol 7 (10) ◽  
pp. 200834
Author(s):  
Tom Heyman ◽  
Anne-Sofie Maerten

Science is self-correcting, or so the adage goes, but to what extent is that indeed the case? Answering this question requires careful consideration of the various approaches to achieve the collective goal of self-correction. One of the most straightforward mechanisms is individual self-correction: researchers rectifying their own mistakes by publishing a correction notice. Although it offers an efficient route to correcting the scientific record, it has received little to no attention from a metascientific point of view. We aim to fill this void by analysing the content of correction notices published from 2010 until 2018 in the three psychology journals featuring the highest number of corrections over that timespan based on the Scopus database (i.e. Psychological Science with N = 58, Frontiers in Psychology with N = 99 and Journal of Affective Disorders with N = 57). More concretely, we examined which aspects of the original papers were affected (e.g. hypotheses, data-analyses, metadata such as author order, affiliations, funding information etc.) as well as the perceived implications for the papers’ main findings. Our exploratory analyses showed that many corrections involved inconsequential errors. Furthermore, authors rarely revised their conclusions, even though several corrections concerned changes to the results. We conclude with a discussion of current policies, and suggest ways to improve upon the present situation by (i) preventing mistakes, and (ii) transparently rectifying those mistakes that do find their way into the literature.


1969 ◽  
Vol 115 (521) ◽  
pp. 401-406 ◽  
Author(s):  
Desmond Kelly ◽  
C. J. S. Walter

There has been a great deal of argument during the past 30 years about the symptomatic differences between anxiety and depressive states. Mapother (1926) thought that anxiety states should be regarded merely as one of the numerous sub-divisions of the manic-depressive illnesses, since they merged through a series of patients into agitated depression. Lewis (1966) too saw no sharp division between anxiety states and depression and classified agitated depression and anxiety states together as one sub-division of the affective disorders. Garmany (1956, 1958) and Mayer-Gross, Slater and Roth (1960), however, felt that anxiety states and depression were basically different forms of illness.


Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 459
Author(s):  
Giulia Menculini ◽  
Norma Verdolini ◽  
Francesca Brufani ◽  
Valentina Pierotti ◽  
Federica Cirimbilli ◽  
...  

Background and Objectives: Affective disorders, namely bipolar (BDs) and depressive disorders (DDs) are characterized by high prevalence and functional impairment. From a dimensional point of view, BDs and DDs can be considered as psychopathological entities lying on a continuum. A delay in treatment initiation might increase the burden associated with affective disorders. The aim of this study is to analyze the correlates of a long duration of untreated illness (DUI) in these conditions. Materials and Methods: Subjects with BDs and DDs, both in- and outpatients, were recruited. Long DUI was defined according to previous research criteria as >2 years for BDs or >1 year for DDs. Socio-demographic, clinical and psychopathological characteristics of the recruited subjects were collected. Bivariate analyses were performed to compare subjects with a long and short DUI (p < 0.05). Results: In our sample (n = 61), 34.4% of subjects presented a long DUI. A long DUI was significantly associated with longer overall illness duration (p = 0.022) and a higher rate of psychiatric (p = 0.048) and physical comorbidities (p = 0.023). As for psychopathological features, depressive symptoms were more severe in the long DUI subgroup, as demonstrated by a higher score at the Clinical Global Impression-severity of depression (p = 0.012) item and at the anxiety/depression factor of the Positive and Negative Syndrome Scale (p = 0.041). Furthermore, subjects with a long DUI displayed more severe disruption of circadian rhythms, as evaluated by the Biological Rhythms Interview for Assessment in Neuropsychiatry total (p = 0.044) and social domain (p = 0.005) scores and by the Hamilton Depression Rating Scale diurnal variation items (18a: p = 0.029, 18b: p = 0.047). Conclusions: A long DUI may underpin higher clinical severity, as well as worse illness course and unfavorable prognosis in affective disorders. Intervention strategies targeting comorbidities, depressive symptoms and circadian rhythms may decrease disease burden in subjects with a long DUI.


1972 ◽  
Vol 121 (561) ◽  
pp. 162-166 ◽  
Author(s):  
Clair Gurney ◽  
Martin Roth ◽  
R. F. Garside ◽  
T. A. Kerr ◽  
Kurt Schapira

This is the second of two papers dealing with the classification of affective disorders in which the relationship between anxiety states and depressive illnesses is examined. The question at issue is whether a line of demarcation may be drawn between the two disorders or whether they are more appropriately regarded as merging insensibly along a continuum of affective disturbance.


1962 ◽  
Vol 14 ◽  
pp. 169-257 ◽  
Author(s):  
J. Green

The term geo-sciences has been used here to include the disciplines geology, geophysics and geochemistry. However, in order to apply geophysics and geochemistry effectively one must begin with a geological model. Therefore, the science of geology should be used as the basis for lunar exploration. From an astronomical point of view, a lunar terrain heavily impacted with meteors appears the more reasonable; although from a geological standpoint, volcanism seems the more probable mechanism. A surface liberally marked with volcanic features has been advocated by such geologists as Bülow, Dana, Suess, von Wolff, Shaler, Spurr, and Kuno. In this paper, both the impact and volcanic hypotheses are considered in the application of the geo-sciences to manned lunar exploration. However, more emphasis is placed on the volcanic, or more correctly the defluidization, hypothesis to account for lunar surface features.


1984 ◽  
Vol 75 ◽  
pp. 331-337
Author(s):  
Richard Greenberg

ABSTRACTThe mechanism by which a shepherd satellite exerts a confining torque on a ring is considered from the point of view of a single ring particle. It is still not clear how one might most meaningfully include damping effects and other collisional processes into this type of approach to the problem.


Author(s):  
A. Baronnet ◽  
M. Amouric

The origin of mica polytypes has long been a challenging problem for crystal- lographers, mineralogists and petrologists. From the petrological point of view, interest in this field arose from the potential use of layer stacking data to furnish further informations about equilibrium and/or kinetic conditions prevailing during the crystallization of the widespread mica-bearing rocks. From the compilation of previous experimental works dealing with the occurrence domains of the various mica "polymorphs" (1Mr, 1M, 2M1, 2M2 and 3T) within water-pressure vs temperature fields, it became clear that most of these modifications should be considered as metastable for a fixed mica species. Furthermore, the natural occurrence of long-period (or complex) polytypes could not be accounted for by phase considerations. This highlighted the need of a more detailed kinetic approach of the problem and, in particular, of the role growth mechanisms of basal faces could play in this crystallographic phenomenon.


Author(s):  
T. E. Mitchell ◽  
M. R. Pascucci ◽  
R. A. Youngman

1. Introduction. Studies of radiation damage in ceramics are of interest not only from a fundamental point of view but also because it is important to understand the behavior of ceramics in various practical radiation enyironments- fission and fusion reactors, nuclear waste storage media, ion-implantation devices, outer space, etc. A great deal of work has been done on the spectroscopy of point defects and small defect clusters in ceramics, but relatively little has been performed on defect agglomeration using transmission electron microscopy (TEM) in the same kind of detail that has been so successful in metals. This article will assess our present understanding of radiation damage in ceramics with illustrations using results obtained from the authors' work.


Author(s):  
C. Wiencke ◽  
A. Lauchli

Osmoregulatory mechanisms in algae were investigated mainly from a physiological point of view (KAUSS 1977, HELLEBUST 1976). In Porphyra two osmotic agents, i. e. floridoside/isofloridoside (KAUSS 1968) and certain ions, such as K+ and Na+(EPPLEY et al. 1960) are considered for osmotic balance. Accumulations of ions (particularly Na+) in the cytoplasm during osmotic adaptation is improbable, because the activity of enzymes is generally inhibited by high ionic concentrations (FLOWERS et al. 1977).The cellular organization of Porphyra was studied with special emphasis on the development of the vacuolar system under different hyperosmotic conditions. Porphyra was cultivated at various strengths of the culture medium ASP 12 (PROVASOLI 1961) ranging from normal to 6 times concentrated (6x) culture medium. Por electron microscopy freeze fracturing was used (specimens fixed in 2% glutaraldehyde and incubated in 30% glycerol, preparation in a BALZERS BA 360 M apparatus), because chemical fixation gave poor results.


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