scholarly journals SUCCINIC DEHYDROGENASE IN PIGEON PECTORALIS DURING DISUSE ATROPHY

1965 ◽  
Vol 13 (4) ◽  
pp. 265-269 ◽  
Author(s):  
K. M. CHERIAN ◽  
N. V. VALLYATHAN ◽  
J. C. GEORGE
Keyword(s):  
Enzyme Activity ◽  
White Muscle ◽  
Succinic Dehydrogenase ◽  
General Level ◽  
Disuse Atrophy ◽  
Succinic Dehydrogenase Activity ◽  
Muscle Enzyme ◽  
Mitochondrial Number ◽  
Histochemical Changes ◽  
Muscle Enzyme Activity

Quantitative and histochemical changes in succinic dehydrogenase activity in pigeon breast muscle was studied during one to sixty days of disuse after immobilization of the wings. Muscle enzyme activity was found to decrease from the first day, reaching its lowest level after seven days. Histochemical observations on red and white muscle fibers showed that after seven days atrophy, the majority of red fibers had lower enzyme activity; a few others showed higher activity. In white fibers on the other hand, a uniform increase over normal in enzyme activity and mitochondrial number was seen. These changes in the two types of fibers were less conspicuous during the later stages of atrophy. Thus the general level of oxidative metabolism in muscle as a whole was lowered in spite of the slight increase in level of SDH in white fibers. It is suggested that in both red and white fibers there was a shift, of aerobic to anaerobic metabolism, or vice versa.

scholarly journals Neospora caninum and/or Toxoplasma gondii Seroprevalence: Vaccination against PCV2 and Muscle Enzyme Activity in Seropositive and Seronegative Pigs

2021 ◽  
Vol 9 (5) ◽  
pp. 1097
Author(s):  
Labrini V. Athanasiou ◽  
Vasileios G. Papatsiros ◽  
Victoria M. Spanou ◽  
Eleni G. Katsogiannou ◽  
Anna Dedousi
Keyword(s):  
Enzyme Activity ◽  
Toxoplasma Gondii ◽  
Neospora Caninum ◽  
Human Infection ◽  
Porcine Circovirus ◽  
Muscle Enzyme ◽  
Blood Samples ◽  
Zoonotic Pathogen ◽  
Muscle Enzyme Activity ◽  
Immunofluorescence Antibody

Neospora caninum and Toxoplasma gondii affect both humans and animals worldwide. To investigate their seroprevalence and differences in seropositivity between pigs vaccinated and unvaccinated against porcine circovirus 2 (PCV2), as well as differences in muscle enzyme activity between seropositive and seronegative pigs, blood samples were collected from 380 sows. Antibodies against T. gondii and N. caninum were detected by an indirect immunofluorescence antibody (IFA) assay, while the activities of creatine kinase (CK) and aspartate aminotransferase (AST) were biochemically assessed. Out of the 364 sows finally included in the study, 4.4%, 3.5%, and 0.5% were seropositive to T. gondii, N. caninum, or both. A significantly higher percentage of seropositivity against T. gondii and/or N. caninum in PCV2 unvaccinated pigs compared with vaccinated pigs was observed. Increased serum activities of CK and AST were detected in 71.43% and 100% of only against T. gondii (T+) and 63.64% and 90.91% of only against N. caninum (N+) seropositive sows, respectively, and were significantly higher compared to seronegative animals. T. gondii and N. caninum seropositivity, especially in presumed immunocompromised pigs, and the evidence of muscle damage highlight their importance as a zoonotic pathogen and animal model of human infection, respectively.

scholarly journals EFFECT OF INFECTION WITH M. TUBERCULOSIS AND OF TUBERCULIN SHOCK ON THE SUCCINIC DEHYDROGENASE ACTIVITY OF GUINEA PIG TISSUES

1953 ◽  
Vol 98 (2) ◽  
pp. 99-105 ◽  
Author(s):  
S. N. Chaudhuri ◽  
Samuel P. Martin
Keyword(s):  
Enzyme Activity ◽  
Guinea Pig ◽  
Dehydrogenase Activity ◽  
Guinea Pigs ◽  
Normal Tissue ◽  
Succinic Dehydrogenase ◽  
Tissue Extract ◽  
Succinic Dehydrogenase Activity ◽  
H37rv Strain ◽  
Sublethal Doses

The kidney of guinea pigs infected with the H37Rv and BCG strains of M. tuberculosis showed a diminution in succinic dehydrogenase activity when measured by the tetrazolium technique. This effect was also seen in the liver and spleen of animals infected with the BCG strain. Sensitized animals showed similar results when given tuberculin in sublethal doses. The succinic oxidase was also low in the kidneys of animals infected with the H37Rv strain. The depressed enzyme activity of the tissues of infected animals could be restored to normal by addition of normal tissue extract or dialysate. This suggests that the alteration in tissue metabolism observed in tuberculosis may depend upon the loss of some as yet unidentified factor important for succinic dehydrogenase activity.

Effects of iron deficiency on endurance and muscle enzyme activity in man

1986 ◽  
Vol 18 (2) ◽  
pp. 156???161 ◽  
Author(s):  
FREDRIK CELSING ◽  
EVA BLOMSTRAND ◽  
BJ??RN WERNER ◽  
PETER PIHLSTEDT ◽  
BJ??RN EKBLOM
Keyword(s):  
Enzyme Activity ◽  
Iron Deficiency ◽  
Muscle Enzyme ◽  
Muscle Enzyme Activity

scholarly journals Increased muscle enzyme activity after yoga breathing during an exacerbation of asthma.

Thorax ◽  
1988 ◽  
Vol 43 (9) ◽  
pp. 731-732 ◽  
Author(s):  
F M Tamarin ◽  
R Conetta ◽  
R D Brandstetter ◽  
H Chadow
Keyword(s):  
Enzyme Activity ◽  
Muscle Enzyme ◽  
Muscle Enzyme Activity

Succinic dehydrogenase activity of forelimb and hindlimb muscles of the dystrophic mouse

1984 ◽  
Vol 62 (8) ◽  
pp. 905-911 ◽  
Author(s):  
D. J. Parry ◽  
G. Desypris
Keyword(s):  
Enzyme Activity ◽  
Succinic Dehydrogenase ◽  
Muscle Fibres ◽  
Image Analyzer ◽  
Dystrophic Muscle ◽  
Hindlimb Muscles ◽  
Fast Twitch ◽  
Whole Muscle ◽  
Histochemical Changes ◽  
Dystrophic Mice

The activity of succinic dehydrogenase (SDH) was determined in muscles of normal and dystrophic mice. In contradistinction to reports based solely upon histochemical examination, we were unable to observe increased activity in fast-twitch muscles of dystrophic mice. Because dystrophic muscles contain large amounts of connective tissue, two reference bases for expression of enzyme activity were compared. SDH activity was expressed either per micromole of creatine or per milligram of "true muscle fibre weight." The latter was obtained by determining the proportion of the whole muscle occupied by muscle fibres using an image analyzer with photographs of muscle cross section. It appears that the use of creatine content as an index of muscle mass may not be valid for pathological tissue, as the concentration of creatine in some dystrophic muscles differed from that of control muscles. Hindlimb muscles of dystrophic mice exhibit continuous spontaneous activity. To determine the effects of this on oxidative enzyme activity two fast-twitch muscles from the forelimb were also examined. Although they showed histochemical changes comparable to those seen in hindlimb muscles, there was no increase in SDH activity. The only dystrophic muscle examined which showed a change in SDH activity was the soleus in which a decrease was observed.

Changes in succinic dehydrogenase activity related to feeding

1961 ◽  
Vol 201 (1) ◽  
pp. 37-40 ◽  
Author(s):  
R. R. Nielson ◽  
H. M. Klitgaard
Keyword(s):  
Enzyme Activity ◽  
Dehydrogenase Activity ◽  
Succinic Dehydrogenase ◽  
Feeding Period ◽  
Succinic Dehydrogenase Activity ◽  
Fasting Period ◽  
Psoas Muscles ◽  
Liver And Kidney ◽  
Effect Of Feeding ◽  
Feeding And Fasting

The effect of feeding and fasting on succinic dehydrogenase activity in rats accustomed to a feeding regime (fed 5 hr/24 hr) was studied over a 24-hr period and over a subsequent extended fast. The results showed a fall in enzyme activity to a minimal value at 6 hr after the initial feeding period in the four tissues studied. During the 24-hr period following feeding, cardiac and psoas muscles obtained maximum values which were 134% and 174%, respectively, of the 6-hr value at 18 hr. Liver and kidney attained their maximum values (133% and 174%, respectively) during the second 5-hr feeding period. When the fasting period was extended by omitting the second feeding period, liver and kidney tended to plateau (after their peak at 24 hr) near the 6-hr assay, whereas cardiac and psoas muscles (after their peaks at 24 and 18 hr, respectively) tended to plateau with 145% of the 6-hr activity. Variations related to feeding times, not previously realized, were demonstrated.

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