In Vivo Imaging of Lamina Cribrosa Pores by Adaptive Optics Scanning Laser Ophthalmoscopy

2012 ◽  
Vol 53 (7) ◽  
pp. 4111 ◽  
Author(s):  
Tadamichi Akagi ◽  
Masanori Hangai ◽  
Kohei Takayama ◽  
Atsushi Nonaka ◽  
Sotaro Ooto ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Lamina Cribrosa ◽  
Scanning Laser ◽  
Scanning Laser Ophthalmoscopy

scholarly journals Adaptive optics scanning laser ophthalmoscopy for in vivo imaging of lamina cribrosa

2007 ◽  
Vol 24 (5) ◽  
pp. 1417 ◽  
Author(s):  
Abhiram S. Vilupuru ◽  
Nalini V. Rangaswamy ◽  
Laura J. Frishman ◽  
Earl L. Smith III ◽  
Ronald S. Harwerth ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Lamina Cribrosa ◽  
Scanning Laser ◽  
Scanning Laser Ophthalmoscopy

Handheld adaptive optics scanning laser ophthalmoscope for in vivo imaging of adults and infants (Conference Presentation)

2018 ◽  
Author(s):  
Derek Nankivil ◽  
Francesco LaRocca ◽  
Sina Farsiu ◽  
Joseph A. Izatt ◽  
James M. Polans ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Scanning Laser Ophthalmoscope ◽  
Scanning Laser

Wavefront sensorless multimodal handheld adaptive optics scanning laser ophthalmoscope for in vivo imaging of human retinal cones

2020 ◽  
Author(s):  
Kristen Hagan ◽  
Theodore DuBose ◽  
David Cunefare ◽  
Corey Simmerer ◽  
Gar Waterman ◽  
...  
Keyword(s):  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Scanning Laser Ophthalmoscope ◽  
Scanning Laser

scholarly journals In vivo imaging the photoreceptors in the chicken eye with adaptive optics scanning laser ophthalmoscope

2009 ◽  
Vol 9 (14) ◽  
pp. 79-79 ◽  
Author(s):  
Y. Zhang ◽  
J. Xu ◽  
M. Garcia ◽  
A. Roorda ◽  
C. Wildsoet
Keyword(s):  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Scanning Laser Ophthalmoscope ◽  
Scanning Laser

scholarly journals Characterization of In Vivo Retinal Lesions of Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Sonja G. Karst ◽  
Jan Lammer ◽  
Salma H. Radwan ◽  
Hanna Kwak ◽  
Paolo S. Silva ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Adaptive Optics ◽  
Scattered Light ◽  
Disease Onset ◽  
Morphological Characteristics ◽  
Response To Therapy ◽  
Vascular Lesions ◽  
Scanning Laser ◽  
Scanning Laser Ophthalmoscopy

Purpose. To characterize hallmark diabetic retinopathy (DR) lesions utilizing adaptive optics scanning laser ophthalmoscopy (AOSLO) and to compare AOSLO findings with those on standard imaging techniques. Methods. Cross-sectional study including 35 eyes of 34 study participants. AOSLO confocal and multiply scattered light (MSL) imaging were performed in eyes with DR. Color fundus photographs (CF), infrared images of the macula (Spectralis, Heidelberg), and Spectralis spectral domain optical coherence tomography SDOCT B-scans of each lesion were obtained and registered to corresponding AOSLO images. Main Outcome Measures. Individual lesion characterization by AOSLO imaging. AOSLO appearance was compared with CF and SDOCT imaging. Results. Characterized lesions encompassed 52 microaneurysms (MA), 20 intraretinal microvascular abnormalities (IRMA), 7 neovascularization (NV), 11 hard exudates (HE), 5 dot/blot hemorrhages (HEM), 4 cotton wool spots (CWS), and 14 intraretinal cysts. AOSLO allowed assessment of perfusion in vascular lesions and enabled the identification of vascular lesions that could not be visualized on CF or SDOCT. Conclusions. AOSLO imaging provides detailed, noninvasive in vivo visualization of DR lesions enhancing the assessment of morphological characteristics. These unique AOSLO attributes may enable new insights into the pathological changes of DR in response to disease onset, development, regression, and response to therapy.

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