scholarly journals Connective Tissue Structure of the Tree Shrew Optic Nerve and Associated Ageing Changes

2007 ◽  
Vol 48 (5) ◽  
pp. 2134 ◽  
Author(s):  
Julie Albon ◽  
Sarah Farrant ◽  
Saeed Akhtar ◽  
Rob Young ◽  
Mike E. Boulton ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Connective Tissue ◽  
Tree Shrew ◽  
Tissue Structure ◽  
Connective Tissue Structure

Identification of Genes Differentially Regulated in Rat Alveolar Bone Wound Healing by Subtractive Hybridization

2004 ◽  
Vol 83 (7) ◽  
pp. 546-551 ◽  
Author(s):  
T. Ohira ◽  
F. Myokai ◽  
N. Shiomi ◽  
K. Yamashiro ◽  
T. Yamamoto ◽  
...  
Keyword(s):  
Wound Healing ◽  
Connective Tissue ◽  
Type I Collagen ◽  
Alveolar Bone ◽  
Subtractive Hybridization ◽  
Tissue Structure ◽  
Type I ◽  
Expression Of Genes ◽  
Periodontal Healing ◽  
Connective Tissue Structure

Periodontal healing requires the participation of regulatory molecules, cells, and scaffold or matrix. Here, we hypothesized that a certain set of genes is expressed in alveolar bone wound healing. Reciprocal subtraction gave 400 clones from the injured alveolar bone of Wistar rats. Identification of 34 genes and analysis of their expression in injured tissue revealed several clusters of unique gene regulation patterns, including the up-regulation at 1 wk of cytochrome c oxidase regulating electron transfer and energy metabolism, presumably occurring at the site of inflammation; up-regulation at 2.5 wks of pro-α-2 type I collagen involving the formation of a connective tissue structure; and up-regulation at 1 and 2 wks and down-regulation at 2.5 and 4 wks of ubiquitin carboxyl-terminal hydrolase l3 involving cell cycle, DNA repair, and stress response. The differential expression of genes may be associated with the processes of inflammation, wound contraction, and formation of a connective tissue structure.

scholarly journals Express diagnosis of connective tissue dysplasia in conditions of ambulatory-polyclinic service

2018 ◽  
Vol 35 (5) ◽  
pp. 36-41
Author(s):  
A. S. Denisov ◽  
D. P. Zagorak
Keyword(s):  
Connective Tissue ◽  
Motor System ◽  
Primary Diagnosis ◽  
The State ◽  
Tissue Structure ◽  
Additional Stabilization ◽  
Connective Tissue Dysplasia ◽  
Connective Tissue Pathology ◽  
Connective Tissue Structure ◽  
Healthy Persons

Aim. To detect the most informative signs of connective tissue dysplasia (CTD) and develop the method for CTD express diagnosis in conditions of ambulatory and stationary traumatologo-orthopedic service. Materials and methods. Sixty practically healthy persons were examined. To diagnose the connective tissue pathology, there were used the criteria developed by S.K. Evtushenko (2002), T.Yu. Smolnova (2003) and T.I. Kartunova (2006). Eighteen the most informative criteria were chosen. Results. The paper is devoted to a widespread and yet not fully studied problem – the connective tissue dysplasia. The basic signs of this disease were analyzed. The most informative criteria of connective tissue dysplasia were singled out. Express test for primary diagnosis of this pathology in conditions of traumatologo-orthopedic service was offered. Conclusions. Express test of the state of connective tissue structure is simple to perform. It can be used to improve surgical aids in connective tissue dysplasia, when additional stabilization of loco motor system is required.

scholarly journals Targeting Polymeric Nanobiomaterials as a Platform for Cartilage Tissue Engineering

2019 ◽  
Vol 25 (17) ◽  
pp. 1915-1932 ◽  
Author(s):  
Jomarien García-Couce ◽  
Amisel Almirall ◽  
Gastón Fuentes ◽  
Eric Kaijzel ◽  
Alan Chan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Articular Cartilage ◽  
Connective Tissue ◽  
Human Body ◽  
Cartilage Tissue Engineering ◽  
Review Article ◽  
Tissue Structure ◽  
Cartilage Tissue ◽  
Nanoscale Structures ◽  
Connective Tissue Structure

Articular cartilage is a connective tissue structure that is found in anatomical areas that are important for the movement of the human body. Osteoarthritis is the ailment that most often affects the articular cartilage. Due to its poor intrinsic healing capacity, damage to the articular cartilage is highly detrimental and at present the reconstructive options for its repair are limited. Tissue engineering and the science of nanobiomaterials are two lines of research that together can contribute to the restoration of damaged tissue. The science of nanobiomaterials focuses on the development of different nanoscale structures that can be used as carriers of drugs / cells to treat and repair damaged tissues such as articular cartilage. This review article is an overview of the composition of articular cartilage, the causes and treatments of osteoarthritis, with a special emphasis on nanomaterials as carriers of drugs and cells, which reduce inflammation, promote the activation of biochemical factors and ultimately contribute to the total restoration of articular cartilage.

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