scholarly journals Express diagnosis of connective tissue dysplasia in conditions of ambulatory-polyclinic service

2018 ◽  
Vol 35 (5) ◽  
pp. 36-41
Author(s):  
A. S. Denisov ◽  
D. P. Zagorak
Keyword(s):  
Connective Tissue ◽  
Motor System ◽  
Primary Diagnosis ◽  
The State ◽  
Tissue Structure ◽  
Additional Stabilization ◽  
Connective Tissue Dysplasia ◽  
Connective Tissue Pathology ◽  
Connective Tissue Structure ◽  
Healthy Persons

Aim. To detect the most informative signs of connective tissue dysplasia (CTD) and develop the method for CTD express diagnosis in conditions of ambulatory and stationary traumatologo-orthopedic service. Materials and methods. Sixty practically healthy persons were examined. To diagnose the connective tissue pathology, there were used the criteria developed by S.K. Evtushenko (2002), T.Yu. Smolnova (2003) and T.I. Kartunova (2006). Eighteen the most informative criteria were chosen. Results. The paper is devoted to a widespread and yet not fully studied problem – the connective tissue dysplasia. The basic signs of this disease were analyzed. The most informative criteria of connective tissue dysplasia were singled out. Express test for primary diagnosis of this pathology in conditions of traumatologo-orthopedic service was offered. Conclusions. Express test of the state of connective tissue structure is simple to perform. It can be used to improve surgical aids in connective tissue dysplasia, when additional stabilization of loco motor system is required.

scholarly journals Connective Tissue Structure of the Tree Shrew Optic Nerve and Associated Ageing Changes

2007 ◽  
Vol 48 (5) ◽  
pp. 2134 ◽  
Author(s):  
Julie Albon ◽  
Sarah Farrant ◽  
Saeed Akhtar ◽  
Rob Young ◽  
Mike E. Boulton ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Connective Tissue ◽  
Tree Shrew ◽  
Tissue Structure ◽  
Connective Tissue Structure

Identification of Genes Differentially Regulated in Rat Alveolar Bone Wound Healing by Subtractive Hybridization

2004 ◽  
Vol 83 (7) ◽  
pp. 546-551 ◽  
Author(s):  
T. Ohira ◽  
F. Myokai ◽  
N. Shiomi ◽  
K. Yamashiro ◽  
T. Yamamoto ◽  
...  
Keyword(s):  
Wound Healing ◽  
Connective Tissue ◽  
Type I Collagen ◽  
Alveolar Bone ◽  
Subtractive Hybridization ◽  
Tissue Structure ◽  
Type I ◽  
Expression Of Genes ◽  
Periodontal Healing ◽  
Connective Tissue Structure

Periodontal healing requires the participation of regulatory molecules, cells, and scaffold or matrix. Here, we hypothesized that a certain set of genes is expressed in alveolar bone wound healing. Reciprocal subtraction gave 400 clones from the injured alveolar bone of Wistar rats. Identification of 34 genes and analysis of their expression in injured tissue revealed several clusters of unique gene regulation patterns, including the up-regulation at 1 wk of cytochrome c oxidase regulating electron transfer and energy metabolism, presumably occurring at the site of inflammation; up-regulation at 2.5 wks of pro-α-2 type I collagen involving the formation of a connective tissue structure; and up-regulation at 1 and 2 wks and down-regulation at 2.5 and 4 wks of ubiquitin carboxyl-terminal hydrolase l3 involving cell cycle, DNA repair, and stress response. The differential expression of genes may be associated with the processes of inflammation, wound contraction, and formation of a connective tissue structure.

scholarly journals SEX AND AGE CHARACTERISTICS OF RATE OF PHISICAL DEVELOPMENT OF CHILDREN OF THE NORTERN REGION WITH ESTABLISHED UNDIFFERENTIATED CONNECTIVE TISSUE DISPLASION

2021 ◽  
Vol 27 (1) ◽  
pp. 44-49
Author(s):  
Igor Andreevich Shevnin ◽  
◽  
Natalya Aleksandrovna Ilyushchenko ◽  
Olga Vasilievna Ragosina
Keyword(s):  
Environmental Factors ◽  
Connective Tissue ◽  
Physical Development ◽  
The State ◽  
Standard Of Living ◽  
State Of Health ◽  
Ecological Zones ◽  
Child Population ◽  
High Prevalence ◽  
Connective Tissue Dysplasia

The tempo characteristic of the physical development of children demonstrates the state of health of the younger generation, refl ecting the standard of living of the population in various climatic and ecological zones, as well as the infl uence of environmental factors. In view of the high prevalence of undiff erentiated forms of connective tissue dysplasia among the child population of the KhMAO – Yugra, it is necessary to study the infl uence of the dysplastic process on the processes of ontogenesis and organogenesis

scholarly journals Method of diagnostics of undifferentiated connective tissue dysplasia

2021 ◽  
Vol 25 (2(98)) ◽  
pp. 114-118
Author(s):  
O. Usenko ◽  
Ya. Voitiv ◽  
S. Shcherbyna
Keyword(s):  
Statistical Analysis ◽  
Connective Tissue ◽  
Comparison Group ◽  
Morphological Changes ◽  
Surgical Pathology ◽  
Main Attention ◽  
White Line ◽  
Connective Tissue Dysplasia ◽  
Immunohistochemical Studies ◽  
Connective Tissue Pathology

Objective – to develop a method for diagnosing undifferentiated connective tissue dysplasia (UCTD) in patients with surgical pathology.Material and methods. The object of the study comprises 96 patients with surgical pathology who were treated in the department of thoracoabdominal surgery of the Shalimov National Institute of Surgery and Transplantology during 2017-2020 and 20 practically healthy people (comparison group). Laboratory, instrumental, histological, immunohistochemical studies and statistical analysis were performed.Results. The developed method contains an assessment of the most informative phenotypic and visceral signs of connective tissue pathology. The main attention is paid to the features that characterize the visceral manifestations of UDCT, especially functional and morphological changes of the digestive organs, which is extremely important in abdominal surgery. Ultrasonography is used to analyze the width of the white line of the abdomen and the condition of the abdominal and retroperitoneal organs, determining the presence of diastase of the rectus abdominis and splanchnoptosis. Studies of the effectiveness of the proposed method have shown that it can be used to diagnose UDCT in patients with surgical pathology, which is necessary to select effective treatment tactics and prevent complications in such patients.Conclusions. A method for diagnosing undifferentiated connective tissue dysplasia has been developed, which evaluates the most informative phenotypic signs of connective tissue pathology and considers the peculiarities of pathology in patients of a surgical hospital.

scholarly journals FEATURES OF APONEUROSIS PATHOMORPHOLOGICAL CHANGES IN PATIENTS WITH EVENTRATION

2021 ◽  
Vol 19 (4) ◽  
Author(s):  
Ya.Yu Voitiv ◽  
O.O. Dyadyk
Keyword(s):  
Smooth Muscle ◽  
Monoclonal Antibodies ◽  
Connective Tissue ◽  
Vascular Wall ◽  
Collagen Iv ◽  
Treatment Results ◽  
Positive Expression ◽  
Connective Tissue Dysplasia ◽  
Connective Tissue Pathology

Objective – to improve the treatment results of patients with eventration by determiningthe role of undifferentiated connective tissue dysplasia in the development of thiscomplication.Material and methods. The object of the study comprises 33 patients with eventrationwho were treated in the department of thoracoabdominal surgery of Shalimov NationalInstitute of Surgery and Transplantology during 2017-2020.Results. At complex pathomorphological research of aponeurosis fragments similarmorphological changes have been revealed in groups of patients with phenotypic signsof undifferentiated connective tissue dysplasia and eventration. Immunohistochemicalexamination of tissues with monoclonal antibodies to α-SMA revealed uneven, focalexpression in smooth muscle differentiation cells and fibroblasts in both groups. In thestudies with monoclonal antibodies to Collagen IV, moderate positive expression in thebasement membrane of the blood vessels, in smooth muscle cells of the muscular layerof the vascular wall, in areas of the connective tissue was observed, that is a sign ofpathological remodeling of the connective tissue.Conclusions. Similar pathomorphological changes of the aponeurosis in groups withphenotypic signs of undifferentiated connective tissue dysplasia and post-operativeeventration confirm the role of the connective tissue pathology in the development of thiscomplication.

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