Development of the Anticancer Potential of a Chlorogenate-Zinc Layered Hydroxide Nanohybrid with Controlled Release Property Against Various Cancer Cells

2013 ◽  
Vol 5 (12) ◽  
pp. 1983-1993 ◽  
Author(s):  
Farahnaz Barahuie ◽  
Mohd Zobir Hussein ◽  
Palanisamy Arulselvan ◽  
Sharida Fakurazi ◽  
Zulkarnain Zainal
Keyword(s):  
Controlled Release ◽  
Cancer Cells ◽  
Release Property ◽  
Zinc Layered Hydroxide

Evaluation of Controlled-Release Property and Phytotoxicity Effect of Insect Pheromone Zinc-Layered Hydroxide Nanohybrid Intercalated with Hexenoic Acid

2015 ◽  
Vol 63 (51) ◽  
pp. 10893-10902 ◽  
Author(s):  
Rozita Ahmad ◽  
Mohd Zobir Hussein ◽  
Wan Rasidah Wan Abdul Kadir ◽  
Siti Halimah Sarijo ◽  
Taufiq-Yap Yun Hin
Keyword(s):  
Controlled Release ◽  
Insect Pheromone ◽  
Release Property ◽  
Zinc Layered Hydroxide

scholarly journals Anticancer nanodelivery system with controlled release property based on protocatechuate–zinc layered hydroxide nanohybrid

2014 ◽  
pp. 3137 ◽  
Author(s):  
Farahnaz Barahuie ◽  
Mohd Zobir Hussein ◽  
Shafinaz Abd Gani ◽  
Sharida Fakurazi ◽  
Zulkarnain Zainal
Keyword(s):  
Controlled Release ◽  
Release Property ◽  
Zinc Layered Hydroxide

scholarly journals pH and redox dual-sensitive drug delivery system constructed based on fluorescent carbon dots

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2656-2663
Author(s):  
Boye Zhang ◽  
Qianqian Duan ◽  
Yi Li ◽  
Jianming Wang ◽  
Wendong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Ph Responsive ◽  
Charge Reversal ◽  
Fluorescent Carbon Dots

The system is pH-responsive and redox-controlled release. And the charge reversal and size transitions of the system can enhance the targeted ability. Moreover, the system can recognize the cancer cells by the fluorescence imaging.

Intelligent micro-vehicles for drug transport and controlled release to cancer cells

2021 ◽  
pp. 104961
Author(s):  
Marieta Constantin ◽  
Sanda Bucatariu ◽  
Irina Popescu ◽  
Bogdan Cosman ◽  
Paolo Ascenzi ◽  
...  
Keyword(s):  
Controlled Release ◽  
Cancer Cells ◽  
Drug Transport

Targeting cancer cells with controlled release nanocapsules based on a single aptamer

2013 ◽  
Vol 49 (13) ◽  
pp. 1285 ◽  
Author(s):  
Frank J. Hernandez ◽  
Luiza I. Hernandez ◽  
Alessandro Pinto ◽  
Thomas Schäfer ◽  
Veli C. Özalp
Keyword(s):  
Controlled Release ◽  
Cancer Cells

scholarly journals Controlled release formulation of an anti-depression drug based on a L-phenylalanate-zinc layered hydroxide intercalation compound

2017 ◽  
Vol 105 ◽  
pp. 35-44 ◽  
Author(s):  
Norhayati Hashim ◽  
Sharifah Norain Mohd Sharif ◽  
Illyas Md Isa ◽  
Shahidah Abdul Hamid ◽  
Mohd Zobir Hussein ◽  
...  
Keyword(s):  
Controlled Release ◽  
Intercalation Compound ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide

scholarly journals Synthesis, Characterization, and Evaluation of Genistein-Loaded Zein/Carboxymethyl Chitosan Nanoparticles with Improved Water Dispersibility, Enhanced Antioxidant Activity, and Controlled Release Property

Foods ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1604
Author(s):  
Yu Xiao ◽  
Chi-Tang Ho ◽  
Yulian Chen ◽  
Yuanliang Wang ◽  
Zihao Wei ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Controlled Release ◽  
Water Solubility ◽  
Uv Light ◽  
Chitosan Nanoparticles ◽  
Carboxymethyl Chitosan ◽  
Food Ingredient ◽  
Beneficial Effects ◽  
Release Property ◽  
Water Dispersibility

Genistein is one of major isoflavones derived from soybean products and it is believed to have beneficial effects on human health. However, its low water-solubility and poor oral bioavailability severely hamper its use as a functional food ingredient or for pharmaceutical industry. In this study, zein and zein/carboxymethyl chitosan (CMCS) nanoparticles were prepared to encapsulate genistein using a combined liquid–liquid phase separation method. The physicochemical properties of fabricated nanoparticles were characterized by dynamic light scattering (DLS), atomic force microscopy (AFM), and Fourier transform infrared spectroscopy (FTIR). The results demonstrated that genistein encapsulated with zein nanoparticles significantly improved its water dispersibility, antioxidant activity in the aqueous phase, and photostability against UV light. Moreover, genistein encapsulated in zein nanoparticles showed a sustained release property. Furthermore, it was found that encapsulation efficiency of genistein was significantly enhanced after CMCS coating, and this effect was more pronounced after the complex nanoparticles cross-linked with calcium ions when compared with the use of zein as a single encapsulant. In addition, compared to zein nanoparticles without biopolymer coating, CMCS coating significantly enhanced the thermal and storage stability of the formed nanoparticles, and delayed the release of genistein. A schematic diagram of zein and zein/carboxymethyl chitosan (CMCS) nanoparticles formation mechanism for encapsulation of genistein was proposed. According to the results of the current study, it could be concluded that encapsulation of genistein in zein/CMCS nanoparticles is a promising approach to improve its water dispersibility, antioxidant activity, photostability against UV light and provide controlled release for food/pharmaceutical applications.

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