scholarly journals Controlled-release formulation of antihistamine based on cetirizine zinc-layered hydroxide nanocomposites and its effect on histamine release from basophilic leukemia (RBL-2H3) cells

2012 ◽  
pp. 3351 ◽  
Author(s):  
Samer Hussein Al Ali ◽  
Samer Hussein Al Ali ◽  
Mohd Zobir Hussein ◽  
Zulkarnain Zainal ◽  
Muhammad Nazrul-Hakim ◽  
...  
Keyword(s):  
Controlled Release ◽  
Histamine Release ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide ◽  
Basophilic Leukemia

scholarly journals Controlled release formulation of an anti-depression drug based on a L-phenylalanate-zinc layered hydroxide intercalation compound

2017 ◽  
Vol 105 ◽  
pp. 35-44 ◽  
Author(s):  
Norhayati Hashim ◽  
Sharifah Norain Mohd Sharif ◽  
Illyas Md Isa ◽  
Shahidah Abdul Hamid ◽  
Mohd Zobir Hussein ◽  
...  
Keyword(s):  
Controlled Release ◽  
Intercalation Compound ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide

scholarly journals Herbicide-Intercalated Zinc Layered Hydroxide Nanohybrid for a Dual-Guest Controlled Release Formulation

2012 ◽  
Vol 13 (6) ◽  
pp. 7328-7342 ◽  
Author(s):  
Mohd Zobir Hussein ◽  
Nor Shazlirah Shazlyn Abdul Rahman ◽  
Siti H. Sarijo ◽  
Zulkarnain Zainal
Keyword(s):  
Controlled Release ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide

scholarly journals Synthesis and Characteristics of Valeric Acid-Zinc Layered Hydroxide Intercalation Material for Insect Pheromone Controlled Release Formulation

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Rozita Ahmad ◽  
Mohd Zobir Hussein ◽  
Siti Halimah Sarijo ◽  
Wan Rasidah Wan Abdul Kadir ◽  
Taufiq-Yap Yun Hin
Keyword(s):  
Controlled Release ◽  
Release Kinetics ◽  
Intercalation Compound ◽  
Valeric Acid ◽  
Insect Pheromone ◽  
Basal Spacing ◽  
Order Kinetic ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide

A new intercalation compound of insect pheromone, valeric acid (VA), based on zinc layered hydroxide (ZLH) as host release material, was successfully prepared through coprecipitation method. The as-produced organic-inorganic nanolayered material, valerate nanohybrid, VAN, shows the formation of a new peak at lower 2θ angle with basal spacing of 19.8 Å with no ZnO reflections, which indicate that the intercalation of anion between the inorganic ZLH interlamellae was accomplished. The elemental, FTIR, and ATR analyses of the nanohybrid supported the fact that the intercalation with the percentage anion loading was calculated to be 23.0% (w/w). The thermal stability property of the resulting nanohybrid was enhanced compared to the unbound anion. Field emission scanning electron micrograph of the ZnO has a nonuniform granular structure but transforms into flake-like structure with various sizes after the intercalation process. Release kinetics of anion from the interlayer of intercalated compound exhibited a slow release behavior governed by the pseudo-second-order kinetic model at different pHs of aqueous media. The valerate anion was released from VAN with the highest release rate at pH 4. These findings provide the basis to further development of controlled release formulation for insect pheromone based on ZLH intercalation.

Optimization Study to Develop Once-a-day Controlled Release Formulation of Metoclopramide with Predictable Design Space

1970 ◽  
Vol 1 (1) ◽  
pp. 71-76
Author(s):  
Rajesh Dubey ◽  
Udaya K. Chowdary ◽  
Venkateswarlu V.
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Design Space ◽  
Release Kinetics ◽  
Release Profile ◽  
Release Formulation ◽  
Linear Effect ◽  
Controlled Release Formulation ◽  
The Difference ◽  
Face Centered

A controlled release formulation of metoclopramide was developed using a combination of hypromellose (HPMC) and hydrogenated castor oil (HCO). Developed formulations released the drug over 20 hr with release kinetics following Higuchi model. Compared to HCO, HPMC showed significantly higher influence in controlling the drug release at initial as well as later phase. The difference in the influence can be explained by the different swelling and erosion behaviour of the polymers. Effect of the polymers on release was optimized using a face-centered central composite design to generate a predictable design space. Statistical analysis of the drug release at various levels indicated a linear effect of the polymers’ levels on the drug release. The release profile of formulations containing the polymer levels at extremes of their ranges in design space was found to be similar to the predicted release profile

Using a reactive emulsifier to construct simple and convenient nanocapsules loaded with lambda-cyhalothrin to achieve efficient foliar delivery and insecticidal synergies

Nanoscale ◽  
2021 ◽  
Author(s):  
Jian Luo ◽  
Yue Gao ◽  
Yukun Liu ◽  
Jiang Du ◽  
Da-xia Zhang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Pest Control ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Lambda Cyhalothrin ◽  
Complicated Process ◽  
Convenient Preparation ◽  
Cost Limit

Nanocapsules are a promising controlled release formulation for foliar pest control. However, the complicated process and high cost limit widespread use in agriculture, so a simpler and more convenient preparation...

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