scholarly journals Cannabis, Ischemic Stroke, and Transient Ischemic Attack: A Case-Control Study

Stroke ◽  
2013 ◽  
Vol 44 (8) ◽  
pp. 2327-2329 ◽  
Author(s):  
P. A. Barber ◽  
H. M. Pridmore ◽  
V. Krishnamurthy ◽  
S. Roberts ◽  
D. A. Spriggs ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Case Control ◽  
Ischemic Attack ◽  
Control Study

scholarly journals Population-Based Case–Control Study of White Matter Changes on Brain Imaging in Transient Ischemic Attack and Ischemic Stroke

Stroke ◽  
2013 ◽  
Vol 44 (11) ◽  
pp. 3063-3070 ◽  
Author(s):  
Linxin Li ◽  
Michela Simoni ◽  
Wilhelm Küker ◽  
Ursula G. Schulz ◽  
Sharon Christie ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
White Matter ◽  
Brain Imaging ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
White Matter Changes ◽  
Ischemic Attack ◽  
Control Study

scholarly journals Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction

2020 ◽  
Author(s):  
Hao Hao Wang ◽  
Hao Hao Lu ◽  
Xiao-Meng Xiao-Meng Zhang ◽  
Ken-ichiro Ken-ichiro Goto ◽  
Eiichi Eiichi Kobayashi ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cerebral Infarction ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Smoking Habit ◽  
Case Control ◽  
Human Aortic Endothelial Cell ◽  
Ischemic Attack ◽  
Antibody Levels ◽  
Control Study

Abstract Background and Purpose: Ischemic stroke, such as Transient ischemic attack (TIA) and cerebral infarction (CI) , are the serious problems in the aging society. Therefore, development of biomarkers for TIA and CI is attempted.Methods: Candidate antigens recognized by IgG autoantibodies in the sera of nineteen TIA patients were screened by a human aortic endothelial cell cDNA library. Serum antibody levels against the antigens were examined by amplified luminescent proximity homogeneous assay-linked immunosorbent assay (AlphaLISA) in healthy donor (HD), TIA, and CI cohorts (n = 285, 92 and 529). A case-control study nested within the Japan Public Health Center-based Prospective Cohort Study (JPHC) was performed.Results: Aldolase A, fructose-bisphosphate (ALDOA) and fumarate hydratase (FH) were identified as the candidate antigens. AlphaLISA revealed that anti-ALDOA and anti-FH antibody levels were both higher in TIA or CI patients than in HDs ( P < 0.0001). The levels of anti-ALDOA [Odds ratio (OR): 2.46, P = 0.005] and anti-FH (OR: 2.49, P = 0.0037) were independent predictors of TIA by multivariate logistic regression analysis, similar results were found in CI. The case-control study showed the levels of anti-ALDOA (OR: 2.50, P < 0.01) and anti-FH (OR: 2.60, P < 0.01) were associated with risk of CI. Spearman’s correlation analysis demonstrated an association between the anti-ALDOA and anti-FH levels and risk factors of ischemic stroke, such as age, smoking habit, coronary heart disease, and hypertension.Conclusions: Anti-ALDOA and anti-FH antibodies can serve as novel potential biomarkers for prediction of TIA and CI.

Different Risk Factor Profiles between Transient Global Amnesia and Transient Ischemic Attack: A Large Case-Control Study

2013 ◽  
Vol 71 (1-2) ◽  
pp. 19-24 ◽  
Author(s):  
Jae-Won Jang ◽  
So Young Park ◽  
Jeong-Ho Hong ◽  
Young Ho Park ◽  
Jung E. Kim ◽  
...  
Keyword(s):  
Risk Factor ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Transient Global Amnesia ◽  
Case Control ◽  
Global Amnesia ◽  
Ischemic Attack ◽  
Control Study ◽  
Large Case

scholarly journals Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case–control study

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110229
Author(s):  
Ying Li ◽  
Qing-rong Ouyang ◽  
Juan Li ◽  
Xiao-rong Chen ◽  
Lin-lin Li ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Matrix Metalloproteinase ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Matrix Metalloproteinase 2 ◽  
Odds Ratios ◽  
Control Study

Objective To determine the associations between matrix metalloproteinase-2 (MMP-2, encoded by the MMP2 gene) 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke in a Chinese population. Methods Patients with first and recurrent ischemic stroke were included. Serum MMP-2 was measured, and MMP2 1306C/T and 735C/T polymorphisms were detected. The associations between MMP2 1306C/T and 735C/T polymorphisms and first and recurrent ischemic stroke were analyzed. Results Serum MMP-2 in patients with first and recurrent ischemic stroke was significantly higher compared with controls, and patients with recurrent ischemic stroke had higher MMP-2 than those with first ischemic stroke. The frequency of the CC genotype and C allele of MMP2 735C/T was highest in patients with recurrent ischemic stroke, followed by patients with first ischemic stroke, and controls. Conversely, the genotype and allele of MMP2 1306C/T did not significantly differ between groups. The CC genotype of MMP2 735C/T was independently associated with first and recurrent ischemic stroke (odds ratios = 1.45 and 1.64, respectively), as was the C allele of MMP2 735C/T (odds ratios = 1.68 and 1.77, respectively). Conclusions The CC genotype and C allele of MMP2 735C/T were associated with first and recurrent ischemic stroke in a Chinese population.

scholarly journals Risk of ischemic stroke associated to analgesic drugs use: a real world data case-control study

2018 ◽  
Vol 26 ◽  
pp. S225
Author(s):  
R. Vives ◽  
A. Gomez-Lumbreras ◽  
M. Fradera ◽  
M. Giner-Soriano ◽  
A. Garcia-Sangenis ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Real World ◽  
Case Control Study ◽  
Case Control ◽  
Real World Data ◽  
Analgesic Drugs ◽  
World Data ◽  
Control Study
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