scholarly journals Population-Based Case–Control Study of White Matter Changes on Brain Imaging in Transient Ischemic Attack and Ischemic Stroke

Stroke ◽  
2013 ◽  
Vol 44 (11) ◽  
pp. 3063-3070 ◽  
Author(s):  
Linxin Li ◽  
Michela Simoni ◽  
Wilhelm Küker ◽  
Ursula G. Schulz ◽  
Sharon Christie ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
White Matter ◽  
Brain Imaging ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
White Matter Changes ◽  
Ischemic Attack ◽  
Control Study

scholarly journals Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction

2020 ◽  
Author(s):  
Hao Hao Wang ◽  
Hao Hao Lu ◽  
Xiao-Meng Xiao-Meng Zhang ◽  
Ken-ichiro Ken-ichiro Goto ◽  
Eiichi Eiichi Kobayashi ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cerebral Infarction ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Smoking Habit ◽  
Case Control ◽  
Human Aortic Endothelial Cell ◽  
Ischemic Attack ◽  
Antibody Levels ◽  
Control Study

Abstract Background and Purpose: Ischemic stroke, such as Transient ischemic attack (TIA) and cerebral infarction (CI) , are the serious problems in the aging society. Therefore, development of biomarkers for TIA and CI is attempted.Methods: Candidate antigens recognized by IgG autoantibodies in the sera of nineteen TIA patients were screened by a human aortic endothelial cell cDNA library. Serum antibody levels against the antigens were examined by amplified luminescent proximity homogeneous assay-linked immunosorbent assay (AlphaLISA) in healthy donor (HD), TIA, and CI cohorts (n = 285, 92 and 529). A case-control study nested within the Japan Public Health Center-based Prospective Cohort Study (JPHC) was performed.Results: Aldolase A, fructose-bisphosphate (ALDOA) and fumarate hydratase (FH) were identified as the candidate antigens. AlphaLISA revealed that anti-ALDOA and anti-FH antibody levels were both higher in TIA or CI patients than in HDs ( P < 0.0001). The levels of anti-ALDOA [Odds ratio (OR): 2.46, P = 0.005] and anti-FH (OR: 2.49, P = 0.0037) were independent predictors of TIA by multivariate logistic regression analysis, similar results were found in CI. The case-control study showed the levels of anti-ALDOA (OR: 2.50, P < 0.01) and anti-FH (OR: 2.60, P < 0.01) were associated with risk of CI. Spearman’s correlation analysis demonstrated an association between the anti-ALDOA and anti-FH levels and risk factors of ischemic stroke, such as age, smoking habit, coronary heart disease, and hypertension.Conclusions: Anti-ALDOA and anti-FH antibodies can serve as novel potential biomarkers for prediction of TIA and CI.

scholarly journals Cannabis, Ischemic Stroke, and Transient Ischemic Attack: A Case-Control Study

Stroke ◽  
2013 ◽  
Vol 44 (8) ◽  
pp. 2327-2329 ◽  
Author(s):  
P. A. Barber ◽  
H. M. Pridmore ◽  
V. Krishnamurthy ◽  
S. Roberts ◽  
D. A. Spriggs ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Case Control ◽  
Ischemic Attack ◽  
Control Study

scholarly journals Risk of ischemic stroke associated with non-steroidal anti-inflammatory drugs and paracetamol: a population-based case-control study

2015 ◽  
Vol 13 (5) ◽  
pp. 708-718 ◽  
Author(s):  
P. García-Poza ◽  
F. J. de Abajo ◽  
M. J. Gil ◽  
A. Chacón ◽  
V. Bryant ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Control Study

Different Risk Factor Profiles between Transient Global Amnesia and Transient Ischemic Attack: A Large Case-Control Study

2013 ◽  
Vol 71 (1-2) ◽  
pp. 19-24 ◽  
Author(s):  
Jae-Won Jang ◽  
So Young Park ◽  
Jeong-Ho Hong ◽  
Young Ho Park ◽  
Jung E. Kim ◽  
...  
Keyword(s):  
Risk Factor ◽  
Transient Ischemic Attack ◽  
Case Control Study ◽  
Transient Global Amnesia ◽  
Case Control ◽  
Global Amnesia ◽  
Ischemic Attack ◽  
Control Study ◽  
Large Case

Association of ALOX5AP with ischemic stroke: a population-based case-control study

2007 ◽  
Vol 121 (5) ◽  
pp. 601-607 ◽  
Author(s):  
Ritesh Kaushal ◽  
Prodipto Pal ◽  
Kathleen Alwell ◽  
Mary Haverbusch ◽  
Matthew Flaherty ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study
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