Individual and Combined Associations of Fasting Serum Lipids with Incident Risk of First Ischemic Stroke: A Chinese Community-Based Nested Case-Control Study

2020 ◽  
Author(s):  
Yue Zhang ◽  
Jingyi Li ◽  
Chengzhang Liu ◽  
Hongxiang Yu ◽  
Chen Chen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Serum Lipids ◽  
Case Control Study ◽  
Case Control ◽  
Chinese Community ◽  
Fasting Serum ◽  
Community Based ◽  
Nested Case Control ◽  
Control Study

scholarly journals Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Huan Hu ◽  
Chonglei Bi ◽  
Tengfei Lin ◽  
Lishun Liu ◽  
Yun Song ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Stroke Risk ◽  
Case Control Study ◽  
Case Control ◽  
Negative Association ◽  
Community Based ◽  
Plasma Selenium ◽  
Non Linear ◽  
Nested Case Control ◽  
Control Study

Abstract Background To date, there is no clearly defined association between plasma selenium levels and first stroke. We aimed to investigate the association between baseline plasma selenium and first stroke risk in a community-based Chinese population. Methods Using a nested case-control study design, a total of 1255 first stroke cases and 1255 matched controls were analyzed. Participant plasma selenium concentrations were measured by inductively coupled plasma mass spectrometry (ICP-MS), and the association of plasma selenium with first stroke risk was estimated by conditional logistic regression models. Results Overall, a non-linear negative association between plasma selenium and first total stroke and first ischemic stroke risks was found in males but not in females. Compared with participants with lower selenium levels (tertile 1–2, < 94.1 ng/mL), participants with higher selenium levels (tertile 3, ≥ 94.1 ng/mL) had significantly lower risks of first total stroke (OR 0.63; 95% CI 0.48, 0.83) and first ischemic stroke (OR 0.61; 95% CI 0.45, 0.83) in males but not in females with first total stroke (OR 0.92; 95% CI 0.69, 1.22) and first ischemic stroke (OR 0.89; 95% CI 0.65, 1.22). Furthermore, a stronger association between plasma selenium and first total stroke was found in males with higher vitamin E levels (≥ 13.5 μg/mL vs. < 13.5 μg/mL P-interaction = 0.007). No significant association was observed between plasma selenium and first hemorrhagic stroke risk in either males or females. Conclusion Our study indicated a significant, non-linear, negative association between plasma selenium and first stroke in males but not in females. Trial registration ChiCTR1800017274.

scholarly journals Sex Difference in The Association Between Plasma Selenium and First Stroke: A Community-Based Nested Case-Control Study

2021 ◽  
Author(s):  
Huan Hu ◽  
Chonglei Bi ◽  
Tengfei Lin ◽  
Lishun Liu ◽  
Yun Song ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Stroke Risk ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Negative Association ◽  
Community Based ◽  
Plasma Selenium ◽  
Nested Case Control ◽  
Control Study

Abstract Background: To date, there is no clearly defined association between plasma selenium levels and first stroke. We aimed to investigate the association between baseline plasma selenium and first stroke risk in a community-based, Chinese population. Methods: Using a nested case-control study design, a total of 1255 first stroke cases and 1255 matched controls were analyzed. Participant plasma selenium concentrations were measured by inductively coupled plasma mass spectrometry (ICP-MS) and the association of plasma selenium with first stroke risk was estimated by conditional logistic regression models. Results: Overall, a nonlinear negative association between plasma selenium with first total stroke and first ischemic stroke risks was found in males, but not in females. Compared with participants with lower selenium levels (tertile 1-2, <94.1 ng/mL), participants with higher selenium levels (tertile 3, ≥94.1 ng/mL) had significantly lower risks of first total stroke (OR: 0.63; 95% CI: 0.48, 0.83) and first ischemic stroke (OR: 0.61; 95% CI: 0.45, 0.83) in males, but not in females with first total stroke (OR: 0.92; 95% CI: 0.69, 1.22) and first ischemic stroke (OR: 0.89; 95% CI: 0.65, 1.22). Furthermore, a stronger association between plasma selenium and first total stroke was found in males with higher vitamin E levels (≥13.5 μg/mL vs. <13.5 μg/mL P-interaction=0.007). No significant association was observed between plasma selenium and first hemorrhagic stroke risk in either males or females. Conclusion: Our study indicated a significant, nonlinear, negative association between plasma selenium and first stroke in males, but not in females.TRIAL REGISTRATION: ChiCTR1800017274.

Association between CPR-related genetic variants and risk of ischemic stroke: a nested case-control study

2019 ◽  
Vol 41 (12) ◽  
pp. 1090-1096
Author(s):  
Yao Zhu ◽  
Shu-Chang Hu ◽  
Pei-Wen Zheng ◽  
Ming-Juan Jin ◽  
Meng-Ling Tang ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Genetic Variants ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

scholarly journals Suicide by people in a community justice pathway: Population-based nested case–control study

2015 ◽  
Vol 207 (2) ◽  
pp. 175-176 ◽  
Author(s):  
Carlene King ◽  
Jane Senior ◽  
Roger T. Webb ◽  
Tim Millar ◽  
Mary Piper ◽  
...  
Keyword(s):  
Suicide Risk ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Elevated Risk ◽  
Sexual Offences ◽  
Community Based ◽  
Community Justice ◽  
Nested Case Control ◽  
Control Study

SummaryThe elevated risk of suicide in prison and after release is a well-recognised and serious problem. Despite this, evidence concerning community-based offenders' suicide risk is sparse. We conducted a population-based nested case–control study of all people in a community justice pathway in England and Wales. Our data show 13% of general population suicides were in community justice pathways before death. Suicide risks were highest among individuals receiving police cautions, and those having recent, or impending prosecution for sexual offences. Findings have implications for the training and practice of clinicians identifying and assessing suicidality, and offering support to those at elevated risk.

scholarly journals RE: Serum Lipids, Lipoproteins, and Risk of Breast Cancer: A Nested Case-Control Study Using Multiple Time Points

2016 ◽  
Vol 108 (8) ◽  
pp. djw126
Author(s):  
Lisa J. Martin ◽  
Ella Huszti ◽  
Philip W. Connelly ◽  
Cary V. Greenberg ◽  
Salomon Minkin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Serum Lipids ◽  
Case Control Study ◽  
Case Control ◽  
Multiple Time ◽  
Time Points ◽  
Multiple Time Points ◽  
Nested Case Control ◽  
Control Study

scholarly journals Determinants of skilled attendance for delivery in Northwest Ethiopia: a community based nested case control study

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Zelalem Birhanu Mengesha ◽  
Gashaw Andargie Biks ◽  
Tadesse Awoke Ayele ◽  
Gizachew Assefa Tessema ◽  
Digsu Negesse Koye
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Northwest Ethiopia ◽  
Community Based ◽  
Skilled Attendance ◽  
Nested Case Control ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document