Evaluation of Apically Positioned Dental Implants with a Sandblasted with Large Grit and Acid-Etched Surface 1 Day After Initial Placement Using Micro-CT and Nondecalcified Tissue Slide Images in a Rabbit Model

2019 ◽  
Vol 34 (5) ◽  
pp. 1078-1083 ◽  
Author(s):  
Seok-Joon Kang ◽  
Jun-Beom Park ◽  
InSoo Kim ◽  
Won Lee ◽  
Heesung Kim
Keyword(s):  
Dental Implants ◽  
Rabbit Model ◽  
Micro Ct ◽  
Initial Placement ◽  
Etched Surface

scholarly journals Comparison between Sandblasted Acid-Etched and Oxidized Titanium Dental Implants: In Vivo Study

2019 ◽  
Vol 20 (13) ◽  
pp. 3267 ◽  
Author(s):  
Eugenio Velasco-Ortega ◽  
Ivan Ortiz-García ◽  
Alvaro Jiménez-Guerra ◽  
Loreto Monsalve-Guil ◽  
Fernando Muñoz-Guzón ◽  
...  
Keyword(s):  
Residual Stress ◽  
Dental Implants ◽  
Rabbit Model ◽  
Chemical Properties ◽  
In Vivo Study ◽  
Implant Surface ◽  
Bone Response ◽  
Etched Surface ◽  
Titanium Dental Implants

The surface modifications of titanium dental implants play important roles in the enhancement of osseointegration. The objective of the present study was to test two different implant surface treatments on a rabbit model to investigate the osseointegration. The tested surfaces were: a) acid-etched surface with sandblasting treatment (SA) and b) an oxidized implant surface (OS). The roughness was measured by an interferometeric microscope with white light and the residual stress of the surfaces was measured with X-ray residual stress Bragg–Bentano diffraction. Six New Zealand white rabbits were used for the in vivo study. Implants with the two different surfaces (SA and OS) were inserted in the femoral bone. After 12 weeks of implantation, histological and histomorphometric analyses of the blocks containing the implants and the surrounding bone were performed. All the implants were correctly implanted and no signs of infection were observed. SA and OS surfaces were both surrounded by newly formed trabeculae. Histomorphometric analysis revealed that the bone–implant contact % (BIC) was higher around the SA implants (53.49 ± 8.46) than around the OS implants (50.94 ± 16.42), although there were no significant statistical differences among them. Both implant surfaces (SA and OS) demonstrated a good bone response with significant amounts of newly formed bone along the implant surface after 12 weeks of implantation. These results confirmed the importance of the topography and physico–chemical properties of dental implants in the osseointegration.

scholarly journals Bone Density around Titanium Dental Implants Coating Tested/Coated with Chitosan or Melatonin: An Evaluation via Microtomography in Jaws of Beagle Dogs

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 777
Author(s):  
Nansi López-Valverde ◽  
Antonio López-Valverde ◽  
Juan Manuel Aragoneses ◽  
Francisco Martínez-Martínez ◽  
María C. González-Escudero ◽  
...  
Keyword(s):  
Bone Density ◽  
Dental Implants ◽  
Statistical Significance ◽  
Micro Ct ◽  
Beagle Dogs ◽  
Hounsfield Units ◽  
Etched Surface ◽  
And Control ◽  
Titanium Dental Implants ◽  
Different Levels

Peri-implant bone density plays an important role in the osseointegration of dental implants. The aim of the study was to evaluate via micro-CT, in Hounsfield units, the bone density around dental implants coated with chitosan and melatonin and to compare it with the bone density around implants with a conventional etched surface after 12 weeks of immediate post-extraction placement in the jaws of Beagle dogs. Six dogs were used, and 48 implants were randomly placed: three groups—melatonin, chitosan, and control. Seven 10 mm × 10 mm regions of interest were defined in each implant (2 in the crestal zone, 4 in the medial zone, and 1 in the apical zone). A total of 336 sites were studied with the AMIDE tool, using the Norton and Gamble classification to assess bone density. The effect on bone density of surface coating variables (chitosan, melatonin, and control) at the crestal, medial, and apical sites and the implant positions (P2, P3, P4, and M1) was analyzed at bivariate and multivariate levels (linear regression). Adjusted effects on bone density did not indicate statistical significance for surface coatings (p = 0.653) but did for different levels of ROIs (p < 0.001) and for positions of the implants (p = 0.032). Micro-CT, with appropriate software, proved to be a powerful tool for measuring osseointegration.

scholarly journals Influence of the Thermal Treatment to Address a Better Osseointegration of Ti6Al4V Dental Implants: Histological and Histomorphometrical Study in a Rabbit Model

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Antonio Scarano ◽  
Ezio Crocetta ◽  
Alessandro Quaranta ◽  
Felice Lorusso
Keyword(s):  
Thermal Treatment ◽  
Dental Implants ◽  
Bone Healing ◽  
Rabbit Model ◽  
Titanium Implants ◽  
Control Group ◽  
Left Femur ◽  
Bone Response ◽  
First Choice ◽  
Significant Difference

Background. Pure titanium continues to be the first choice for dental implants and represents the gold standard for their biocompatibility and physical and mechanical characteristics, while the titanium alloy (Ti6Al4V) has good mechanical properties. The surface structure of the titanium oxide layer formation on the surface influences and improves the bone response around dental implants. Purpose. The purpose of this study is to evaluate the influence of a thermal treatment of Ti6Al4V implant surfaces and the bone healing response in a rabbit model. Methods. Altogether sixteen implants with same design were inserted into the distal femoral metaphysis. A screw (13 mm long, 4 mm in diameter) was inserted in an implant bed. Each rabbit received two implants, one in the left femur and one in the right femur. The samples were histologically and histomorphometrically evaluated at 8 weeks. Results. A statistically significant difference (p = 0.000034) was present histologically in the percentages of bone-implant contact (BIC) between the test group (BIC = 69.25±4.49%.) and control group (BIC = 56.25 ± 4.8%) by one-way analysis of variance (ANOVA). Significance was set at p ≤ 0.05. Conclusions. The outcome of the present study indicates a novel approach to improving bone healing around titanium implants.

scholarly journals Intermittent administration of parathyroid hormone enhances primary stability of dental implants in a bone-reduced rabbit model

2016 ◽  
Vol 58 (2) ◽  
pp. 241-246 ◽  
Author(s):  
Yoshifumi Oki ◽  
Kazuya Doi ◽  
Yusuke Makihara ◽  
Takayasu Kubo ◽  
Hiroshi Oue ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Dental Implants ◽  
Rabbit Model ◽  
Primary Stability ◽  
Intermittent Administration

scholarly journals Effects of Bisphosphonates on Osseointegration of Dental Implants in Rabbit Model

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Ru Qing Yu ◽  
Jing Yi Wang ◽  
Nian Jing Rao ◽  
Lei Huo ◽  
Li Wu Zheng
Keyword(s):  
Zoledronic Acid ◽  
Dental Implants ◽  
Dental Implant ◽  
Growth Rates ◽  
Acid Treatment ◽  
Bone Growth ◽  
Rabbit Model ◽  
Short Term ◽  
Calvarial Bone

This study is to investigate the effect of bisphosphonates on the osseointegration of dental implants in a rabbit model. Twenty female New Zealand White rabbits were equally assigned into control and experiment groups which received saline or zoledronic acid treatment 4 weeks prior to surgery. Titanium dental implant was placed on the calvarial bone. Zoledronic acid or saline treatment continued after surgery for 4 weeks (short-term subgroup) or 8 weeks (long-term subgroup) until sacrifice. Three different fluorochrome labeling solutions were administrated for assessing bone growth rates. Samples of the calvarial bone and mandible were subjected to microcomputed tomography (micro-CT), confocal microscope, and histology analysis. Zoledronic acid treatment significantly reduced bone growth rates in the calvarial bone, but had no significant influence in bone mineral density and trabecular microarchitecture. Significantly lower bone-to-implant contact ratios were found in zoledronic acid-treated animals compared to controls at week 4 but not at week 8. Oncologic dose zoledronic acid suppresses the bone growth rates of the calvarial bone; ZA may have an adverse effect on osseointegration of dental implant in short term, but this effect tends to diminish in long term.

Implant Surface Conditioning with Tetracycline-HCl: A SEM Study

2007 ◽  
Vol 361-363 ◽  
pp. 849-852 ◽  
Author(s):  
Y. Herr ◽  
J.A. Woo ◽  
Y.H. Kwon ◽  
J.B. Park ◽  
S.J. Heo ◽  
...  
Keyword(s):  
Dental Implants ◽  
Pure Titanium ◽  
Control Group ◽  
Machined Surface ◽  
Implant Surface ◽  
Increased Risk ◽  
Sem Study ◽  
Modified Surface ◽  
Etched Surface ◽  
Tetracycline Hcl

The increased surface roughness of dental implants has shown enhanced integration of bone tissues to implant surfaces, but may be predisposed to an increased risk of pathogenic bacterial infection and contamination with bacterial products. Tetracycline-HCl (Tc) treatment has been regarded as a practical and effective chemical modality for decontamination and detoxification of contaminated implant surfaces. The purpose of this study was to examine if Tc treatment alters the microstructures of the modified surface of dental implants. For this purpose, dental implants with pure titanium machined surface (MS), sandblasted, large grit, acid-etched surface (SLAS), or anodized surface (AS) were used. The surface of dental implants was rubbed for 30, 60, 90, 120, or 150 sec with sponge pellets soaked in Tc solution (50mg/ml) and in distilled water for 0 and 150 sec as the control group. The specimens were then routinely processed for scanning electron microscopy. The results show that Tc treatment did not change the surface of MS, SLAS, and AS.

scholarly journals OP22.07: Cardiac fiber orientation and coronary changes in a rabbit model of IUGR using X-ray phase-contrast synchrotron radiation-based micro-CT

2014 ◽  
Vol 44 (S1) ◽  
pp. 116-116 ◽  
Author(s):  
F. Crispi ◽  
A. Gonzalez-Tendero ◽  
C. Zhang ◽  
V. Balicevic ◽  
R. Cardenas ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Fiber Orientation ◽  
Phase Contrast ◽  
Rabbit Model ◽  
Micro Ct ◽  
X Ray ◽  
Cardiac Fiber
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