scholarly journals Myoepithelial Carcinoma Arising in a Plasmacytoid Myoepithelioma of the Parotid Gland Synchronized with Melanoma: A Case Report and Review of the Literature

2021 ◽  
pp. 173-183
Author(s):  
Pamela Denisse Soberanis-Piña ◽  
Ricardo Fernández-Ferreira ◽  
Héctor Hugo Buerba-Vieregge ◽  
Edgar Varela-Santoyo ◽  
Jerónimo Rafael Rodriguez-Cid ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
English Language ◽  
De Novo ◽  
Complete Response ◽  
Salivary Gland Neoplasm ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nodal Dissection ◽  
Language Literature

Myoepithelial carcinoma, also known as malignant myoepithelioma, is considered an extremely rare (0.45–1%) malignant salivary gland neoplasm. Approximately 100 cases have been reported in the English-language literature on myoepithelial carcinoma. The majority of the myoepitheliomas described in the literature have been benign, and the malignant counterpart is considered rare (<1%). Such a tumor may appear de novo or rarely develop from a preexisting pleomorphic adenoma (<20%), and in exceedingly rare cases (<0.5%), it has arisen from a benign myoepithelioma (i.e., plasmacytoid myoepithelioma). To our knowledge, no case of myoepithelial carcinoma of the parotid gland arising in a plasmacytoid myoepithelioma synchronized with melanoma has been reported to date. The treatment of myoepithelial carcinoma has been mainly surgical, including wide excision with free margins, with or without nodal dissection. The roles of chemotherapy and radiotherapy have not yet been established. We report a case of myoepithelial carcinoma of the parotid gland arising in a plasmacytoid myoepithelioma synchronized with melanoma in a 40-year-old woman. In our case, a complete response was achieved with surgery followed by adjuvant chemotherapy based on carboplatin and paclitaxel concurrent with radiotherapy.

scholarly journals Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Mark Weitzel ◽  
Jason E. Cohn ◽  
Harvey Spector
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Benign Tumor ◽  
Clinical Presentation ◽  
Acinar Cells ◽  
Salivary Gland Neoplasm ◽  
Minor Salivary Glands ◽  
Review Of The Literature ◽  
Basal Plasma Membrane ◽  
Basal Plasma

Myoepithelioma is a rare salivary gland neoplasm. They most commonly affect the major and minor salivary glands with the parotid gland being the most common, approximately 40%. Only 1% of all salivary gland neoplasms are myoepitheliomas. Myoepithelioma is usually a benign tumor arising from neoplastic myoepithelial or basket cells which are found between the basement membrane and the basal plasma membrane of acinar cells. They also contain multiple cellular elements. We present a case of a 73-year-old female with myoepithelioma of the parotid gland, an extremely rare neoplasm. There have been approximately 42 cases reported through 1985 and fewer than 100 cases through 1993. We will discuss the clinical presentation, pathophysiology, diagnosis, and treatment of such neoplasms.

scholarly journals Pleural fluid metastases of myoepithelial carcinoma: A case report and review of the literature

CytoJournal ◽  
2016 ◽  
Vol 13 ◽  
pp. 13 ◽  
Author(s):  
Alicia Calderon Bhambra ◽  
Yanhong Zhang ◽  
Eric C. Huang ◽  
John Bishop ◽  
Mahan Matin ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleural Fluid ◽  
Rare Case ◽  
De Novo ◽  
Myoepithelial Carcinoma ◽  
Minor Salivary Glands ◽  
Review Of The Literature ◽  
Accurate Identification ◽  
First Case

Myoepithelial carcinoma (MECA) is one of the rarest salivary gland neoplasms, which may either arise de novo or develop within a preexisting pleomorphic adenoma or benign myoepithelioma. The tumor occurs mainly in the parotid gland followed by minor salivary glands and other body sites. As a result of their morphologic heterogeneity, they can be confused easily with many tumors. Awareness of their unique cytoarchitectural patterns and immunohistochemical profile is crucial for accurate identification. Herein, we report a rare case of a 51-year-old female patient with MECA of the maxillary sinus that metastasized to the pleural fluid. To the best of our knowledge, this is the first case of pleural fluid involvement by MECA reported in the literature.

scholarly journals Giant Cell Carcinosarcoma of the Parotid Gland With a PLAG 1 Translocation in Association With a Pleomorphic Adenoma With HMGA2 Translocation

2020 ◽  
Vol 154 (6) ◽  
pp. 811-815
Author(s):  
Levon Katsakhyan ◽  
Virginia A LiVolsi ◽  
Ara A Chalian ◽  
Paul J Zhang
Keyword(s):  
Salivary Gland ◽  
In Situ Hybridization ◽  
Parotid Gland ◽  
Giant Cell ◽  
Pleomorphic Adenoma ◽  
De Novo ◽  
Sarcomatous Component ◽  
Gland Tumor ◽  
Parotid Gland Tumor

Abstract Objectives Carcinosarcomas of the salivary gland are rare neoplasms and have been described arising de novo or in association with pleomorphic adenoma (PA). PLAG1 and HMGA2 translocations are known to occur in PAs and carcinomas ex PA but are mutually exclusive. Methods We report a case of a carcinosarcoma in the parotid gland of a 77-year-old man with unusual anaplastic sarcomatoid giant cell morphology. Results Microscopically, a small separate PA was found adjacent to the carcinosarcoma. By conventional notion, the PA and carcinosarcoma would be considered related, as carcinosarcomas are well known to arise from PAs (carcinosarcoma ex PA). However, fluorescence in situ hybridization (FISH) assay demonstrated PLAG1 translocation in the carcinosarcoma and HMGA2 translocation in the separate PA. Conclusions These findings support that the carcinosarcoma likely originated from another PA with a PLAG1 translocation or de novo but not from the coexisting PA harboring a different translocation. To our knowledge, the case is the first to demonstrate PLAG1 translocation by FISH in a sarcomatous component of any parotid gland tumor, which may help better classify these tumors. In addition, multiple PAs are commonly found in the salivary gland, and to our knowledge, our case is the first to demonstrate that the same parotid gland can host PAs and PA-related tumors with different translocations.

scholarly journals Tubular Type of Basal Cell Adenoma of Parotid Gland: A Rare Entity

2015 ◽  
Vol 5 (3) ◽  
pp. 184-187
Author(s):  
Pratik Dipak Shah ◽  
Srijon Mukherji
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Basal Cell ◽  
Myoepithelial Cell ◽  
Rare Case ◽  
Salivary Gland Neoplasm ◽  
Rare Entity ◽  
Basal Cell Adenoma ◽  
Cell Adenoma ◽  
Tubular Type

ABSTRACT Basal cell adenoma (BCA) is a significantly rare benign salivary gland neoplasm that includes isomorphic basaloid cells. Presence of myoepithelial cell is a characteristic of this tumor. Basal cell adenoma accounts for only 1 to 2% of all salivary gland epithelial tumors. The goal of the paper is to report a rare case of tubular type of BCA arising from parotid gland and discuss its management. How to cite this article Shah PD, Mukherji S. Tubular Type of Basal Cell Adenoma of Parotid Gland: A Rare Entity. J Contemp Dent 2015;5(3):184-187.

Basal cell adenocarcinoma of the parotid gland: a case report and review of the literature

1993 ◽  
Vol 107 (9) ◽  
pp. 862-864 ◽  
Author(s):  
Timo Atula ◽  
Pekka-Juhani Klemi ◽  
Karl Donath ◽  
Risto-Pekka Happonen ◽  
Heikki Joensuu ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Parotid Gland ◽  
Basal Cell ◽  
Mitotic Rate ◽  
Therapeutic Result ◽  
Review Of The Literature ◽  
Total Removal ◽  
Basal Cell Adenocarcinoma ◽  
Gland Tumour

AbstractBasal cell adenocarcinoma is a rare salivary gland tumour. A DNA diploid parotid gland basal cell adenocarcinoma, with a low mitotic rate, in a 78-year-old female patient is described. Total removal of the affected salivary gland without sacrificing the facial nerve gave a good therapeutic result.

Occult Primary Parotid Gland Acinic Cell Adenocarcinoma Presenting With Extensive Lung Metastasis

2007 ◽  
Vol 131 (6) ◽  
pp. 970-973
Author(s):  
Fabio Tavora ◽  
Negar Rassaei ◽  
Konstantin Shilo ◽  
Robert D. Foss ◽  
Jeffrey R. Galvin ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Clinical Evaluation ◽  
Distant Metastases ◽  
Salivary Gland Neoplasm ◽  
Regional Lymph Nodes ◽  
Acinic Cell ◽  
Parotid Carcinoma ◽  
Peripheral Lung ◽  
Gland Type

Abstract Acinic cell adenocarcinoma is a malignant salivary gland neoplasm with a relatively low rate of lymphangitic spread to regional lymph nodes. Distant metastases are rare and their occurrence typically indicates an unfavorable outcome. We encountered an unusual example of acinic cell adenocarcinoma that initially presented in the lung, whereas the primary parotid carcinoma, despite extensive clinical evaluation, only became apparent 1 year after initial diagnosis. The histologic, immunohistochemical, and ultrastructural features of the tumor in the parotid gland and lung were similar. The tumor displayed an aggressive behavior resulting in death within 2 years of the initial presentation. This presentation is unique, showing that peripheral lung tumors of salivary gland type are likely to be metastatic, and careful clinical evaluation is warranted in establishing their primary site of origin.

scholarly journals A Single Liver Metastasis From Adenoid Cystic Carcinoma of the Parotid Gland: Case Report

2019 ◽  
Vol 7 ◽  
pp. 232470961987963
Author(s):  
Ines Zemni ◽  
Nesrine Tounsi ◽  
Imene Bouraoui ◽  
Maher Slimene ◽  
Ghada Sahraoui ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Liver Metastasis ◽  
Parotid Gland ◽  
Adenoid Cystic Carcinoma ◽  
Malignant Neoplasm ◽  
Salivary Gland Cancer ◽  
Review Of The Literature ◽  
Adenoid Cystic ◽  
Disease Free ◽  
Rare Situation

Adenoid cystic carcinoma is an uncommon malignant neoplasm of the salivary gland. Liver metastasis from salivary gland cancer is a rare situation. In this article, we report the case of a 29-year-old woman treated 5 years previously for adenoid cystic carcinoma of the parotid gland by surgery and radiotherapy, who presented for a large hypervascularized hepatic metastasis of 20 cm. After 3-cycle chemotherapy stability, hepatic surgery was successfully performed. The patient maintained disease-free period of 12 months after the surgical treatment. This rare case represents a therapeutic challenge for oncologists and surgeons. Through this case and a review of the literature, we try to better detail the management of this uncommon entity.

Pectoralis Major Rupture: Presentation of Two Cases and Review of 74 Cases

1997 ◽  
Vol 5 (2) ◽  
pp. 118-122
Author(s):  
Hubert YM Chao ◽  
Ralph T Manktelow
Keyword(s):  
Surgical Management ◽  
Conservative Management ◽  
English Language ◽  
Surgical Repair ◽  
Case Reports ◽  
Pectoralis Major ◽  
Review Of The Literature ◽  
The Past ◽  
Sporting Activities ◽  
Language Literature

Pectoralis major rupture is uncommon. Injury usually occurs from sporting activities. The incidence and management of pectoralis major rupture is not well known, despite 74 case reports in the English language literature over the past 34 years. Two cases of chronic pectoralis ruptures and their successful surgical management are described. A review of the literature shows that most injuries occur at the humeral insertion, and most are complete ruptures. Distinguishing between complete and partial ruptures is important. Complete ruptures are best treated surgically in the acute situation. When chronic complete ruptures present, surgical repair yields fair to good results. Acute partial ruptures can be effectively managed conservatively or with surgery. Chronic partial ruptures can be managed surgically with good results, following unsatisfactory conservative management in the acute situation.

Isoniazid-Associated Psychosis: Case Report and Review of the Literature

1993 ◽  
Vol 27 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Karen A. Pallone ◽  
Morton P. Goldman ◽  
Matthew A. Fuller
Keyword(s):  
Case Report ◽  
English Language ◽  
Case Reports ◽  
Data Extraction ◽  
Data Sources ◽  
Review Of The Literature ◽  
Data Synthesis ◽  
Medline Search ◽  
Study Selection ◽  
Language Literature

Objective To describe a case of isoniazid-associated psychosis and review the incidence of this adverse effect. Data Sources Information about the patient was obtained from the medical chart. A MEDLINE search of the English-language literature published from 1950 to 1992 was conducted and Index Medicus was manually searched for current information. Study Selection All case reports describing isoniazid-associated psychosis were reviewed. Data Extraction Studies were evaluated for the use of isoniazid, symptoms of psychosis, onset of symptoms, and dosage of isoniazid. Data Synthesis The case report is compared with others reported in the literature. The incidence of isoniazid-associated psychosis is rare. Conclusions The mechanism of isoniazid-associated psychosis is uncertain. It appears that isoniazid was associated with the psychosis evident in our patient and in the cases reviewed.

scholarly journals Association between biomechanical parameters and concussion in helmeted collisions in American football: a review of the literature

2012 ◽  
Vol 33 (6) ◽  
pp. E10 ◽  
Author(s):  
Jonathan A. Forbes ◽  
Ahmed J. Awad ◽  
Scott Zuckerman ◽  
Kevin Carr ◽  
Joseph S. Cheng
Keyword(s):  
English Language ◽  
American Football ◽  
Rotational Acceleration ◽  
Review Of The Literature ◽  
Biomechanical Parameters ◽  
The Mean ◽  
The Relationship ◽  
Associated Variables ◽  
Translational Acceleration ◽  
Language Literature

Object The authors' goal was to better define the relationship between biomechanical parameters of a helmeted collision and the likelihood of concussion. Methods The English-language literature was reviewed in search of scholarly articles describing the rotational and translational accelerations observed during all monitored impact conditions that resulted in concussion at all levels of American football. Results High school players who suffer concussion experience an average of 93.9g of translational acceleration (TA) and 6505.2 rad/s2 of rotational acceleration (RA). College athletes experience an average of 118.4g of TA and 5311.6 rad/s2 of RA. While approximately 3% of collisions are associated with TAs greater than the mean TA associated with concussion, only about 0.02% of collisions actually result in a concussion. Associated variables that determine whether a player who experiences a severe collision also experiences a concussion remain hypothetical at present. Conclusions The ability to reliably predict the incidence of concussion based purely on biomechanical data remains elusive. This study provides novel, important information that helps to quantify the relative insignificance of biomechanical parameters in prediction of concussion risk. Further research will be necessary to better define other factors that predispose to concussion.

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