Basal cell adenocarcinoma of the maxillary sinus: A case report

Background: A basal cell adenocarcinoma (BCAC) is a low-grade malignancy of the salivary glands. A BCAC of the minor salivary gland is a rare disease, which is extremely rare in the maxillary sinus without invading from the palate and buccal mucosa. The histopathological characteristics of a BCAC are similar to those of a basal cell adenoma (BCA). However, BCAC can be differentiated from BCA based on its tendency to invade surrounding tissues. Surgical resection is the first-line treatment for BCACs. We report a case of a BCAC arising from the maxillary sinus minor salivary glands in an 82-year-old man.Case presentation: In 2016, the patient presented with recurrent epistaxis, and he was referred to our department because a tumor was found in his left nasal cavity. Gross resection using the Denker operation was performed. Histopathological examination revealed no surrounding tissue invasion; therefore, BCA was diagnosed. In 2017, the recurrent lesion was resected using endoscopy as much as possible, and the histopathologic findings again revealed a BCA.In 2019, he developed diplopia, frequent epistaxis, and buccal swelling. The recurrence of maxillary sinus tumor was shown again with invasion of surrounding tissues, and we presumed a clinical diagnosis of a left maxillary carcinoma (suspected BCAC). When we performed partial maxillary resection by the Weber–Ferguson incision, we found that the tumor had partially invaded the bone of the orbital floor; thus, the floor of the orbit and orbital fat were partially resected. Finally, the tumor was diagnosed as a BCAC. Conclusion: We report a BCAC arising from the maxillary sinus. This is an extremely rare sinus tumor, and differentiation of BCAC and BCA is important from a clinical or histopathological examination. A partial maxillectomy with a Weber–Ferguson incision was required for complete resection. When a malignancy is suspected in the recurrent maxillary sinus tumor, it is important to have a wider surgical field than that of the previous surgery to ensure complete resection.

Basal cell adenocarcinoma of the maxillary sinus: A case report

Basal cell adenocarcinoma is a low-grade malignancy of the salivary glands. Basal cell adenocarcinoma of the minor salivary gland is an extremely rare disease that originates from the maxillary sinus. The histopathological characteristics of basal cell adenocarcinomas are similar to those of basal cell adenomas. However, basal cell adenocarcinomas can be differentiated from basal cell adenomas based on their tendency to invade surrounding tissues. Surgical resection is the first-line treatment for basal cell adenocarcinomas. An 86-year-old man underwent operations for a maxillary sinus tumor twice in our department. The pathological results of the tumor at both times revealed basal cell adenoma. After 4 and 5 years since the last operation, the tumor recurred, and the patient was treated with partial maxillectomy using Weber–Ferguson incision. We observed invasions to the surrounding tissue, and based on immunohistochemical findings, the patient was diagnosed with basal cell adenocarcinoma. Herein, we present an extremely rare case of basal cell adenocarcinoma arising from the maxillary sinus, in detail.

Basal Cell Adenoma: About Four Cases

Benign tumor of the salivary glands, composed of basaloid cells of architecture most often ductal and tubular or in nests (OMS 2017). We report the case of 4 patients carrying basal cell adenoma diagnosed at the department of pathological anatomy CHU MOHAMMED VI MARRAKECH. These are three women and one man. The average age was 49 years old. The clinical examination found a unilateral parotid mass gradually increasing in size. All the patients benefited from an ultrasound which was in favor of a homogeneous hypoechoic lobulated formation with posterior reinforcement evoking a pleomorphic adenoma. The patients benefited from a total parotidectomy. Macroscopic examination found a thick-walled, hemorrhagic-cystic formation in one patient. Microscopic examination showed a benign encapsulated tumor proliferation of compact architecture, in situ clusters and in channels with eosinophilic contents. . The epithelial cells have a basaloid appearance bordered at the periphery by a palisade cell base. They are of small to medium size, provided with ovoid cores with fine chromatin. The cytoplasm is abundant basophilic. The myoepithelial cells are sometimes cuboid, sometimes fusiform. The nuclei are discreetly elongated hyperchromic. The cytoplasm is scarce eosinophilic.The basal cell adenoma is a rare salivary tumor representing less than 3.7%. It occurs mainly in the elderly with a range of 57 to 70 years. Clinically, it is in most cases a mobile solitary mass of firm consistency. The tumor has a monomorphic appearance due to the predominance of basaloid cells. The differential diagnosis is primarily with basal cell adenocarcinoma and adenoid cystic carcinoma.