Relationships between Head Circumference Percentile, Lumbar Puncture Pressure, and Cerebrospinal Fluid Space in Young Children: Increased Cerebrospinal Space and Pressure May Result in Compensatory Enlargement of Head Circumference Only in the Infant Period

2019 ◽  
Vol 54 (6) ◽  
pp. 386-393
Author(s):  
Myeong Jin Kim ◽  
Dae Han Choi ◽  
Chan Jong Yoo ◽  
Yong Cheol Lim ◽  
Soo Han Yoon
2010 ◽  
Vol 23 (2) ◽  
pp. 330-331
Author(s):  
Brendan Silbert ◽  
David Scott ◽  
Lisbeth Evered ◽  
Paul Maruff

The growing need for lumbar puncture in order to obtain cerebrospinal fluid (CSF) for the diagnosis Alzheimer's disease is becoming increasingly apparent (Herskovits and Growdon, 2010). The concept of a CSF sampling unit specializing in lumbar puncture would seem the most plausible solution. Physicians and interns are not necessarily skilled in the procedure and neurologists perform lumbar puncture rarely.


2003 ◽  
Vol 181 (1) ◽  
pp. 231-234 ◽  
Author(s):  
Ursula Kiechl-Kohlendorfer ◽  
Karin Maria Unsinn ◽  
Barbara Schlenck ◽  
Rudolph Trawöger ◽  
Ingmar Gaßner

2021 ◽  
pp. 197140092110551
Author(s):  
Robert Heider ◽  
Peter G Kranz ◽  
Erin Hope Weant ◽  
Linda Gray ◽  
Timothy J Amrhein

Rationale and Objectives Accurate cerebrospinal fluid (CSF) pressure measurements are critical for diagnosis and treatment of pathologic processes involving the central nervous system. Measuring opening CSF pressure using an analog device takes several minutes, which can be burdensome in a busy practice. The purpose of this study was to compare accuracy of a digital pressure measurement device with analog manometry, the reference gold standard. Secondary purpose included an assessment of possible time savings. Materials and Methods This study was a retrospective, cross-sectional investigation of 71 patients who underwent image-guided lumbar puncture (LP) with opening CSF pressure measurement at a single institution from June 2019 to September 2019. Exclusion criteria were examinations without complete data for both the digital and analog measurements or without recorded needle gauge. All included LPs and CSF pressures were measured with the patient in the left lateral decubitus position, legs extended. Acquired data included (1) digital and analog CSF pressures and (2) time required to measure CSF pressure. Results A total of 56 procedures were analyzed in 55 patients. There was no significant difference in mean CSF pressures between devices: 22.5 cm H2O digitally vs 23.1 analog ( p = .7). Use of the digital manometer resulted in a time savings of 6 min (438 s analog vs 78 s digital, p < .001). Conclusion Cerebrospinal fluid pressure measurements obtained with digital manometry demonstrate comparable accuracy to the reference standard of analog manometry, with an average time savings of approximately 6 min per case.


2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S292-S292 ◽  
Author(s):  
Christopher Ouellette ◽  
Andrea Ronchi ◽  
Asuncion Mejias ◽  
Susana Chavez-Bueno ◽  
Douglas Salamon ◽  
...  

2014 ◽  
Vol 25 (5) ◽  
pp. 249-251 ◽  
Author(s):  
Ryota Hase ◽  
Naoto Hosokawa ◽  
Makito Yaegashi ◽  
Kiyoharu Muranaka

Elevation of cerebrospinal fluid (CSF) cell count is a key sign in the diagnosis of bacterial meningitis. However, there have been reports of bacterial meningitis with no abnormalities in initial CSF testing. This type of presentation is extremely rare in adult patients. Here, a case involving an 83-year-old woman who was later diagnosed with bacterial meningitis caused byNeisseria meningitidisis described, in whom CSF at initial and second lumbar puncture did not show elevation of cell counts. Twenty-six non-neutropenic adult cases of bacterial meningitis in the absence of CSF pleocytosis were reviewed. The frequent causative organisms wereStreptococcus pneumoniaeandN meningitidis. Nineteen cases had bacteremia and seven died. The authors conclude that normal CSF at lumbar puncture at an early stage cannot rule out bacterial meningitis. Therefore, repeat CSF analysis should be considered, and antimicrobial therapy must be started immediately if there are any signs of sepsis or meningitis.


2018 ◽  
Vol 14 (11) ◽  
pp. 1505-1521 ◽  
Author(s):  
Leslie M. Shaw ◽  
Jalayne Arias ◽  
Kaj Blennow ◽  
Douglas Galasko ◽  
Jose Luis Molinuevo ◽  
...  

PEDIATRICS ◽  
1972 ◽  
Vol 50 (2) ◽  
pp. 346-347
Author(s):  
J. Hower ◽  
H. E. Clar ◽  
M. Düchting

We read Dr. Bray's communication with great interest. With actually three cases of aqueductal stenosis after mumps being recorded we cannot doubt that the experimental findings of Johnson and Johnson have a bearing on human pathology. Our patient, a 6½-year-old boy, underwent evaluation of his megacephalus five months before the onset of mumps. At that time a pneumoencephalogram could be obtained by lumbar filling. Cerebrospinal fluid flow was considered marginally adequate. Three months after mumps meningoencephalitis the patient presented with symptoms of increased intracranial pressure (papilledema, sudden increase in head circumference, and widening of the coronar suture).


2019 ◽  
pp. 1-22
Author(s):  
Janet R. Gilsdorf

Before the advent of antibiotics, meningitis was a dreadful infection by any standard; many of its victims were young children, and almost all died, succumbing to the disease from days to six weeks, or sometimes longer, after the onset of their illness. Incredibly, patients occasionally survived but were often left with varying degrees of neurologic damage. Before the first spinal tap, the diagnosis of meningitis was based on clinical signs and symptoms and could be confirmed only by pathologic examination of the brains of deceased patients during an autopsy. Since the advent of the spinal tap, the diagnosis of meningitis rests on examination of the cerebrospinal fluid. Treatment of meningitis depends on which bacteria cause the infection. Helen Keller may be a famous surviving victim of this disease.


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