scholarly journals Outcomes of Baked Milk and Egg Challenge in Cow’s Milk and Hen’s Egg Allergy: Can Tolerance Be Predicted with Allergen-Specific IgE and Prick-to-Prick Test?

2019 ◽  
Vol 180 (4) ◽  
pp. 264-273
Author(s):  
Seda Sirin Kose ◽  
Suna Asilsoy ◽  
Nevin Uzuner ◽  
Ozkan Karaman ◽  
Ozden Anal
Keyword(s):  
Specific Ige ◽  
Cow’S Milk ◽  
Egg Allergy ◽  
Prick Test ◽  
Cow's Milk ◽  
Hen’S Egg ◽  
Baked Milk

Baked Tolerance in Cow’s Milk Allergy: Quite Frequent, Hard to Predict!

2020 ◽  
pp. 1-5
Author(s):  
Lisis Karine Vilar ◽  
Flávia Alves Araújo ◽  
Thalita Pereira Santos ◽  
Thatiana Tavares Menezes ◽  
Marina F. Cheik ◽  
...  
Keyword(s):  
Food Challenge ◽  
Specific Ige ◽  
Cross Sectional Study ◽  
Cow’S Milk ◽  
Cross Sectional ◽  
Prick Test ◽  
Cow's Milk ◽  
Baked Goods ◽  
Baked Foods ◽  
Baked Milk

<b><i>Introduction:</i></b> Cow’s milk protein allergy (CMA) is the most common type of food allergy in childhood and exclusion diet is a challenge for patients. <b><i>Objective:</i></b> The study aim was to investigate the frequency of tolerance to baked foods containing milk and evaluate immediate skin prick test (SPT) and specific IgEs for different cow’s milk (CM) protein types as predictors of tolerance to baked foods containing milk for CMA patients. <b><i>Methods:</i></b> A cross-sectional study was performed. Fifty-four CMA patients were enrolled and oral food challenge (OFC) was performed with baked product, 6 different milk SPTs and specific IgEs to CM, casein, α-lactalbumin, and β-lactoglobulin. <b><i>Results:</i></b> Thirty-nine (72.2%) patients tolerated OFC with baked milk cupcake. CM-specific IgE and casein SPT showed statistical difference between positive and negative OFC groups. Probability curves for baked milk tolerance were created for specific CM IgE (<i>Z</i> = 2.542, <i>p</i> &#x3c; 0.0110) and casein SPT (<i>Z</i> = 2.290, <i>p</i> &#x3c; 0.0220) using logistic regression. <b><i>Conclusions:</i></b> The high percentage of patients able to tolerate baked goods enables an improvement in intake possibilities and quality of life of CMA patients and families. Specific CM IgE and casein SPT demonstrated to be useful predictors in relation to baked milk tolerance.

Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy

2004 ◽  
Vol 114 (2) ◽  
pp. 387-391 ◽  
Author(s):  
Lynette P.C. Shek ◽  
Lars Soderstrom ◽  
Staffan Ahlstedt ◽  
Kirsten Beyer ◽  
Hugh A. Sampson
Keyword(s):  
Specific Ige ◽  
Cow’S Milk ◽  
Egg Allergy ◽  
Cow's Milk ◽  
Hen’S Egg ◽  
Food Specific Ige ◽  
Over Time ◽  
Development Of Tolerance

scholarly journals Evaluation of some predictive parameters for baked milk tolerance in children with cow's milk allergy

2021 ◽  
Vol 49 (2) ◽  
pp. 53-59
Author(s):  
Mehmet Kilic ◽  
Lütfiye Çilkol ◽  
Erdal Taşkın
Keyword(s):  
Immunoglobulin E ◽  
Food Challenge ◽  
Cow’S Milk ◽  
Milk Products ◽  
Prick Test ◽  
Cow's Milk ◽  
Predictive Parameters ◽  
Decision Points ◽  
Ige Mediated ◽  
Baked Milk

Background: Inclusion of baked-milk products to the diet appears to markedly accelerate tolerance to unheated milk compared to a strict avoidance diet.Objective: The present study aims to investigate the predictors of baked-milk tolerance in children with Immunoglobulin E (IgE)-mediated cow’s milk (CM) allergy.Methods: The study included 80 patients diagnosed with IgE-mediated CM allergy upon oral food challenge (OFC) testing at our clinic. Patients who developed and did not develop reactions during OFC with baked milk were compared considering clinical and laboratory parameters.Results: Eighty patients with CM allergy comprised 48 male and 32 female infants with an average age of 7.25 ± 2.45 (3–13) months. We found that 62.5% of them showed tolerance to baked milk in the OFC test performed with cakes containing 2.6-g milk protein. When the patients who tolerated and could not tolerate baked-milk products were compared for test results, we detected a statistically significant intergroup difference regarding diameter of wheal in skin prick test (SPT) performed with muffin slurry, levels of specific Immunoglobulin E (sIgE) in CM, sheep’s milk (SM), goat’s milk (GM), casein, and the amount of unheated milk consumed until a reaction developed in the OFC test performed with unheated milk (P < 0.05).Conclusion: We defined novel decision points based on CM, SM, GM, casein sIgE levels, wheal diameter in SPT with muffin slurry, and the amount of milk ingested during OFC performed with unheated milk that may be useful in predicting outcomes of baked-milk ingestion.

The patch test, skin prick test, and serum milk-specific IgE as diagnostic tools in cow's milk allergy in infants

Allergy ◽  
1999 ◽  
Vol 54 (8) ◽  
pp. 837-842 ◽  
Author(s):  
T Vanto ◽  
A Koivikko ◽  
E Valovirta ◽  
K Juntunen-backman ◽  
T Klemola ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
Patch Test ◽  
Specific Ige ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Diagnostic Tools ◽  
Milk Allergy ◽  
Prick Test ◽  
Cow's Milk ◽  
Cow's Milk Allergy

Atopy patch test in children with cow's milk and hen's egg allergy: Do clinical symptoms matter?

2020 ◽  
Vol 48 (4) ◽  
pp. 323-331
Author(s):  
S. Sirin Kose ◽  
S. Asilsoy ◽  
D. Tezcan ◽  
G. Atakul ◽  
S. Al ◽  
...  
Keyword(s):  
Patch Test ◽  
Clinical Symptoms ◽  
Cow’S Milk ◽  
Atopy Patch Test ◽  
Egg Allergy ◽  
Cow's Milk ◽  
Hen’S Egg
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