scholarly journals Moderate Frequency of Anti-Thyroglobulin Antibodies in the Early Phase of Subacute Thyroiditis

2019 ◽  
Vol 8 (5) ◽  
pp. 268-272 ◽  
Author(s):  
Eijun Nishihara ◽  
Nobuyuki Amino ◽  
Takumi Kudo ◽  
Kazuyoshi Kohsaka ◽  
Mitsuru Ito ◽  
...  
1960 ◽  
Vol XXXIII (III) ◽  
pp. 457-472 ◽  
Author(s):  
B.-A. Lamberg ◽  
G. Hintze ◽  
R. Jussila ◽  
M. Berlin

ABSTRACT A series of cases of clinically diagnosed subacute thyroiditis comprising 11 patients is reported. Studies on the iodine metabolism, electrophoretic distribution of the serum proteins and the responsiveness to TSH were carried out. The patients were observed for periods up to 16 months from the onset of the disease. In the early phase there was an elevation of the serum PBI in a few cases and hyperthyroid signs in some, accompanied by depressed thyroid uptake of radioactive iodine and a fairly good response to TSH. Later, the thyroid grew hard and the iodine metabolism changed. In several cases there was a marked increase in the conversion ratio and the serum PB131I level. The responses to TSH was variable for different parameters of thyroid function, suggesting a state of »low thyroid reserve« as defined by Jefferies et al. (1956). Hypothyroidism developed in 3 cases; in two of them there was a response to exogenous TSH, in the third no response was seen at this stage of the disease. Cortisone and synthetic analogues seem to be of great benefit in the treatment of the acute symptoms of the disease.


1987 ◽  
Vol 34 (6) ◽  
pp. 821-829 ◽  
Author(s):  
CHIAKI SHIGEMASA ◽  
KYOJU ABE ◽  
SHIN-ICHI TANIGUCHI ◽  
YASUO MITANI ◽  
YOSHIHIKO UETA ◽  
...  

1970 ◽  
Vol 64 (2) ◽  
pp. 359-363 ◽  
Author(s):  
N. J. B. Christiansen ◽  
K. Siersbæk-Nielsen ◽  
J. E.M. Hansen ◽  
L. Korsgaard Christensen

ABSTRACT Serum thyroxine (T4) and other thyroid function tests were studied in 14 patients with subacute thyroiditis and compared with the same parameters in 32 patients with untreated thyrotoxicosis. The mean values of serum T4 and protein-bound iodine (PBI) were found to be elevated to the same extent in the two groups and the calculated T4 iodine did not differ significantly from the PBI in any of the groups. The resin-T3-test and the basal metabolic rate (BMR) mean values were significantly lower in patients with subacute thyroiditis than in patients with thyrotoxicosis. The serum T4 determination based on competitive protein-binding was not influenced by other organic iodinated products, and our results indicate that the elevated serum PBI in subacute thyroiditis is largely due to T4. The lower BMR in patients with subacute thyroiditis is possibly explained by a difference in the thyroxine binding protein (TBP) binding capacity and free T4 in the serum between patients with subacute thyroiditis and those with thyrotoxicosis.


1977 ◽  
Vol 44 (6) ◽  
pp. 1107-1114 ◽  
Author(s):  
ALBERT C. WEIHL ◽  
GILBERT H. DANIELS ◽  
E. CHESTER RIDGWAY ◽  
FARAHE MALOOF

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