scholarly journals Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies

2018 ◽  
Vol 10 (2) ◽  
pp. 207-212 ◽  
Author(s):  
Keiko Hatano ◽  
Hideyuki Matsumoto ◽  
Akihiko Mitsutake ◽  
Junko Yoshimura ◽  
Aya Nomura ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Glutamate Receptor ◽  
Rare Diseases ◽  
Limbic Encephalitis ◽  
Recovery Phase ◽  
Autoimmune Limbic Encephalitis ◽  
Receptor Antibodies

We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence.

Autoantibodies against Glutamate Receptor ε2-Subunit Detected in a Subgroup of Patients with Reversible Autoimmune Limbic Encephalitis

2007 ◽  
Vol 58 (3) ◽  
pp. 152-158 ◽  
Author(s):  
A. Kimura ◽  
T. Sakurai ◽  
Y. Suzuki ◽  
Y. Hayashi ◽  
I. Hozumi ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
Limbic Encephalitis ◽  
Autoimmune Limbic Encephalitis

A case of acute limbic encephalitis associated with SLE accompanied with anti-glutamate receptor antibodies

2012 ◽  
Vol 52 (8) ◽  
pp. 545-550 ◽  
Author(s):  
Yoshitaka Yamaguchi ◽  
Manabu Wada ◽  
Keiji Kurita ◽  
Yukitoshi Takahashi ◽  
Takeo Kato
Keyword(s):  
Glutamate Receptor ◽  
Limbic Encephalitis ◽  
Receptor Antibodies

scholarly journals Atypical Association of Autoimmune Limbic Encephalitis with Anti-NMDA Receptor Antibodies in a Young Male Patient: Clinical, Imaging, and Neuropsychological Characteristics

2021 ◽  
pp. 541-548
Author(s):  
José Alberto Choreño-Parra ◽  
Tania de la Rosa-Arredondo ◽  
André Garibay-Gracián ◽  
Ingrid Montes de Oca-Vargas ◽  
Deyanira Capi-Casillas ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Limbic Encephalitis ◽  
Psychiatric Symptoms ◽  
Brain Mri ◽  
Clinical Manifestations ◽  
Memory Loss ◽  
Autoimmune Encephalitis ◽  
Young Male ◽  
Autoimmune Limbic Encephalitis ◽  
Receptor Antibodies

The spectrum of autoimmune encephalitis (AE) encompasses several entities characterized by a variable frequency of psychiatric symptoms, cognitive dysfunction, focal deficits, and seizures. Although patients with AE can be categorized in specific syndromes, overlapping manifestations are also common. Furthermore, atypical correlations between clinical phenotypes and autoantibody profiles could occur in rare cases. Here, we report the rare case of a young adult man attending due to new-onset seizures and a history of memory loss, autonomic disturbances, headache, behavioral changes, and visual and olfactory hallucinations. The patient was subjected to a complete diagnostic approach that included a comprehensive laboratory workup, neuropsychological testing, electroencephalogram, cerebrospinal fluid (CSF) analysis, brain MRI, and positron emission tomography/computed tomography scan that revealed a functional and structural compromise of the bilateral medial temporal lobes. Together with the clinical manifestations of the patient, these findings were compatible with the diagnosis of autoimmune limbic encephalitis (ALE). Strikingly, further analysis of the CSF showed autoantibodies against the N-methyl-D-aspartate (NMDA) receptor. We found very few cases of the co-occurrence of anti-NMDA receptor antibodies and nonparaneoplastic ALE in the literature, especially in male patients. Our report exemplifies the complicated differential diagnosis of ALE and adds clinical information of the association with anti-NMDA receptor antibodies.

ASL MRI and 18F-FDG-PET in autoimmune limbic encephalitis: clues from two paradigmatic cases

2021 ◽  
Author(s):  
Alessandro Dinoto ◽  
Marta Cheli ◽  
Miloš Ajčević ◽  
Franca Dore ◽  
Carmelo Crisafulli ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Limbic Encephalitis ◽  
Autoimmune Limbic Encephalitis ◽  
18F Fdg

Botryoid nuclei of neutrophils and monocytes in autoimmune limbic encephalitis

2012 ◽  
Vol 95 (4) ◽  
pp. 329-330 ◽  
Author(s):  
Akihito Fujimi ◽  
Yuki Ikeda ◽  
Kaoru Ono ◽  
Yuji Kanisawa
Keyword(s):  
Limbic Encephalitis ◽  
Autoimmune Limbic Encephalitis
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