Water-Soluble Vitamins in Human Milk Factors Affecting Their Concentration and Their Physiological Significance

Author(s):  
Lindsay H. Allen ◽  
Daniela Hampel
PEDIATRICS ◽  
1982 ◽  
Vol 70 (3) ◽  
pp. 499-499
Author(s):  
Joseph A. Little

I was happy to read the report from Greer et al.1 This biochemically confirms the clinical observation that the majority of children who develop clinical rickets are breast-fed. During the ten years, 1970-1979, I have seen six cases of clinical rickets. All of these infants were breast-fed.2 The only exception has been the rickets of prematurity. I should like to commend, again, the report from the Department of Pediatrics and Biochemistry of the University of Wisconsin.


1952 ◽  
Vol 6 (1) ◽  
pp. 215-220 ◽  
Author(s):  
Mavis Gunther
Keyword(s):  

2017 ◽  
Vol 120 ◽  
pp. 20-26 ◽  
Author(s):  
Mara Zambruni ◽  
Alex Villalobos ◽  
Anoma Somasunderam ◽  
Sarah Westergaard ◽  
Maitreyee Nigalye ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1500
Author(s):  
Yarden Golan ◽  
Yehuda G. Assaraf

Human milk is considered the optimal nutrition for infants as it provides additional attributes other than nutritional support for the infant and contributes to the mother’s health as well. Although breastfeeding is the most natural modality to feed infants, nowadays, many mothers complain about breastfeeding difficulties. In addition to environmental factors that may influence lactation outcomes including maternal nutrition status, partner’s support, stress, and latching ability of the infant, intrinsic factors such as maternal genetics may also affect the quantitative production and qualitative content of human milk. These genetic factors, which may largely affect the infant’s growth and development, as well as the mother’s breastfeeding experience, are the subject of the present review. We specifically describe genetic variations that were shown to affect quantitative human milk supply and/or its qualitative content. We further discuss possible implications and methods for diagnosis as well as treatment modalities. Although cases of nutrient-deficient human milk are considered rare, in some ethnic groups, genetic variations that affect human milk content are more abundant, and they should receive greater attention for diagnosis and treatment when necessary. From a future perspective, early genetic diagnosis should be directed to target and treat breastfeeding difficulties in real time.


2011 ◽  
Vol 21 (7) ◽  
pp. 504-508 ◽  
Author(s):  
Sarka Rockova ◽  
Jiri Nevoral ◽  
Vojtech Rada ◽  
Petr Marsik ◽  
Jan Sklenar ◽  
...  
Keyword(s):  

Nutrients ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 381 ◽  
Author(s):  
Alejandra Wiedeman ◽  
Kyly Whitfield ◽  
Kaitlin March ◽  
Nancy Chen ◽  
Hou Kroeun ◽  
...  

1999 ◽  
Vol 8 (2) ◽  
pp. 69-75 ◽  
Author(s):  
Michael Oladipo Ogundele

Several natural components abundant in the fluid phase of human breast-milk have been shown to be inhibitors of complement activationin vitro, particularly the classical pathway. These include lysozyme, lactoferrin, lactalbumin alpha and other ligand chelators, complement regulator proteins and other specific soluble inhibitors of complement activation. Their physiological significance probably resides in their ability to restrictin vivocomplement activation to specialized (compartmentalized) sites on the cellular membrane structures in human milk, represented by the abundant surface area of the milk fat globule membranes. This would serve to prevent inflammatory-induced tissue damage of the delicate immature gastrointestinal tract of the newborn as well as the mammary gland itself. A number of recognized and potential inhibitors of complement activity in human milk and other biological fluids are hereby reviewed, with a proposal of their physiological significance.Abbreviations: HBM, human breast-milk; APC, alternative complement activation pathway; MAC, membrane attack complex (C5b-9); MFGM, milk fat globule membrane


Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1967
Author(s):  
Bianca Enaru ◽  
Georgiana Drețcanu ◽  
Teodora Daria Pop ◽  
Andreea Stǎnilǎ ◽  
Zorița Diaconeasa

Anthocyanins are secondary metabolites and water-soluble pigments belonging to the phenolic group, with important functions in nature such as seed dispersal, pollination and development of plant organs. In addition to these important roles in plant life, anthocyanins are also used as natural pigments in various industries, due to the color palette they can produce from red to blue and purple. In addition, recent research has reported that anthocyanins have important antioxidant, anticancer, anti-inflammatory and antimicrobial properties, which can be used in the chemoprevention of various diseases such as diabetes, obesity and even cancer. However, anthocyanins have a major disadvantage, namely their low stability. Thus, their stability is influenced by a number of factors such as pH, light, temperature, co-pigmentation, sulfites, ascorbic acid, oxygen and enzymes. As such, this review aims at summarizing the effects of these factors on the stability of anthocyanins and their degradation. From this point of view, it is very important to be precisely aware of the impact that each parameter has on the stability of anthocyanins, in order to minimize their negative action and subsequently potentiate their beneficial health effects.


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