Dosage and Blood Levels of Neuroleptics in Tardive Dyskinesia

2015 ◽  
pp. 87-96 ◽  
Author(s):  
Robert C. Smith ◽  
Chandra H. Misra ◽  
Richard Allen ◽  
Jack Gordon
Keyword(s):  
Tardive Dyskinesia ◽  
Blood Levels

Partial Resolution of Tardive Dyskinesia with Treatment of Co-existing Thyrotoxicosis*

1983 ◽  
Vol 28 (2) ◽  
pp. 134-136 ◽  
Author(s):  
Robert Leder ◽  
Darrell Kirch ◽  
Robert Murphy ◽  
Keith Clay ◽  
Robert Freedman
Keyword(s):  
Tardive Dyskinesia ◽  
Blood Levels ◽  
Drug Levels ◽  
Partial Resolution

Neuroleptic-induced tardive dyskinesia improved after treatment of thyrotoxicosis. Neuroleptic blood levels indicated that the improvement was not caused by masking of the symptoms by rising drug levels. Dopamine metabolite measurements suggested that the thyrotoxicosis caused an increase in the sensitivity of caudate neurons to dopamine, rather than a change in release of dopamine.

Treatment of Tardive Dyskinesia: Preliminary Report on Use of Tetrabenazine

1988 ◽  
Vol 33 (1) ◽  
pp. 11-13 ◽  
Author(s):  
Michael W.B. Watson ◽  
David Skelton ◽  
Fakhreddin Jamali
Keyword(s):  
Tardive Dyskinesia ◽  
Biological Samples ◽  
Preliminary Report ◽  
Blood Levels ◽  
The Past

Tetrabenazine has been used for treatment of tardive dyskinesia sporadically over the past twenty years. Dose has usually been decided empirically without assaying blood levels. This report describes 23 cases treated successfully with tetrabenazine. Our method of measuring levels of tetrabenazine and its metabolites in biological samples is described briefly.

scholarly journals Amisulpiride induced tardive dyskinesia: a case report

2018 ◽  
Vol 6 (11) ◽  
pp. 3779
Author(s):  
Dhananjay Chaudhari ◽  
Ganesh Shanker ◽  
Kunjan Gupta
Keyword(s):  
Case Report ◽  
Side Effects ◽  
High Risk ◽  
Tardive Dyskinesia ◽  
Movement Disorders ◽  
Atypical Antipsychotics ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Blood Levels ◽  
Typical Antipsychotics

Amisulpride is a bezamide group of antipsychotic, and like other antipsychotics, it acts by reducing signalling via the dopamine D2 receptor. It is associated with a high risk, of developing increased blood levels of the lactation hormone, prolactin and low risk, as compared with typical antipsychotics, of causing movement disorders. Tardive dyskinesia is a type of movement disorder, which is more common with typical antipsychotics but development of tardive dyskinesia is not rare with the use of atypical antipsychotics. Newer molecules are being developed to reduce the incidence of various dyskinesias, but side effects are evident even with relatively newer molecules. Amisupride is also classed with newer generation of atypical antipsychotic, used to treat schizophrenia and dysthymia. We are reporting a case of middle aged female patient suffering from schizophrenia who developed tardive dyskinesia with the use of amisulpride.

941: Peripheral and Corporal Blood Levels of Preoperative Vancomycin and Gentamycin in Patients Undergoing Penile Prosthesis Implantation

2007 ◽  
Vol 177 (4S) ◽  
pp. 311-312
Author(s):  
Heman Carrion ◽  
Jorge R. Caso ◽  
Gerard D. Henry ◽  
J. Christopher Webster ◽  
Rafael E. Carrion
Keyword(s):  
Penile Prosthesis ◽  
Blood Levels ◽  
Prosthesis Implantation

391 Uric acid blood levels are associated with clinical and echocardiographic parameters of chronic heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 79
Author(s):  
P PAVLIDIS ◽  
J PARISSIS ◽  
S ANTONOPOULOS ◽  
D POLLATOS ◽  
P KIRIAZOPOULOS ◽  
...  
Keyword(s):  
Heart Failure ◽  
Uric Acid ◽  
Chronic Heart Failure ◽  
Blood Levels ◽  
Echocardiographic Parameters

Striae Gravidarum, Vitamin C and Other Related Factors

2011 ◽  
Vol 81 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Rahime Bedir Findik ◽  
Nurcihan Karakurt Hascelik ◽  
Kadir Okhan Akin ◽  
Ayse Nurcan Unluer ◽  
Jale Karakaya
Keyword(s):  
Family History ◽  
Vitamin C ◽  
Pregnant Women ◽  
Smoking Status ◽  
Multiple Logistic Regression Analysis ◽  
Blood Levels ◽  
Significant Relation ◽  
Related Factors ◽  
Thigh Circumference ◽  
Striae Gravidarum

Background: Striae gravidarum, a clinical condition commonly seen in pregnant women, produces serious cosmetic problems and may lead to psychological problems. Aim: The present study investigated whether there was any relation between the presence of striae in primigravid pregnant women and blood vitamin C levels, and factors thought to contribute to the formation of striae such as family history, weight gained during pregnancy, smoking status, abdominal and thigh circumference, and age. Methods: Overall, 69 primigravid women attending routine antenatal follow-up and, using prophylactic iron and vitamin preparations, underwent investigation. All were pregnant 36 or more weeks. Scoring was based on striae examination and whether striae were present. The relation between the presence of striae, vitamin C blood levels, and other factors was investigated. Results and Conclusions: Multiple logistic regression analysis showed a significant relation between the presence of striae and blood vitamin C levels (p = 0.046) and between the presence of striae and family history (p = 0.023). No significant relation was found between the presence of striae and age, weight gained during pregnancy, abdominal and thigh circumference, or smoking status. It was concluded that further, more comprehensive studies on the issue are required.

Tardive Dyskinesia in Elderly Patients

1992 ◽  
Author(s):  
R. Yassa ◽  
C. Natase ◽  
D. Dupont ◽  
M. Thibeau
Keyword(s):  
Elderly Patients ◽  
Tardive Dyskinesia

Increased FDG bone marrow uptake after intracoronary progenitor cell therapy

2005 ◽  
Vol 44 (01) ◽  
pp. 15-19 ◽  
Author(s):  
C. Menzel ◽  
M. Diehl ◽  
N. Hamscho ◽  
K. Zaplatnikov ◽  
F. Grünwald ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Progenitor Cell ◽  
Therapy Monitoring ◽  
Standardized Uptake Value ◽  
Pet Therapy ◽  
Blood Levels ◽  
Bone Marrow Uptake ◽  
Pet Scanning ◽  
Artery Disease ◽  
Nicotine Consumption

SummaryPatients with coronary artery disease who undergo FDG PET for therapy monitoring after intracoronary progenitor cell infusion (PCT) show an increased bone marrow up-take in some cases. Aim of the study was to evaluate the systemic bone marrow glucose metabolism in this patient group after PCT. Patients, methods: FDG bone marrow uptake (BMU), measured as standardized uptake value (SUVmax) in the thoracic spine, was retrospectively evaluated in 23 control patients who did not receive PCT and in 75 patients who received PCT 3 ± 2.2 days before PET scanning. Five out of them were pretreated with granulocyte colony-stimulating factor (G-CSF) 5 days prior to PCT and 10 ± 1.2 days before PET scanning. In 39 patients who received only PCT without G-CSF and underwent PET therapy monitoring 4 months later, baseline and follow up bone marrow uptake were measured. Leucocytes, C-reactive protein (CRP) levels and the influence of nicotine consumption were compared with the BMU. Results: In patients (n = 70) who received PCT without G-CSF, BMU median (1.3) was slightly, but significantly higher than in the controls (1.0) (p = 0.02) regardless nicotine consumption. BMU did not change significantly 4 months later (1.2) (p = 0.41, n.s.). After G-CSF pretreatment, patients showed a significantly higher bone marrow uptake (3.7) compared to patients only treated with PCT (1.3) (p = 0.023). Leucocyte blood levels were significantly higher in patients with a BMU ≥ 2.5 compared to patients with a bone marrow SUVmax < 2.5 (p <0.001). CRP values did not correlate with the BMU (rho -0.02, p = 0.38). Conclusion: Monitoring PCT patients, a slightly increased FDG BMU may be observed which remains unchanged for several months. Unspecific bone marrow reactions after PCT may be associated with increased leucocyte blood levels and play a role in the changed systemic glucose BMU.

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