Influence of Body Temperature on Sodium Excretion after Saline Infusion

2015 ◽  
pp. 84-88
Author(s):  
H. Wirz ◽  
M. Huguenin ◽  
F. Spinelli
Keyword(s):  
Body Temperature ◽  
Sodium Excretion ◽  
Saline Infusion

Renal blood flow, sodium excretion, and concentrating ability during saline infusion

1966 ◽  
Vol 211 (5) ◽  
pp. 1181-1186 ◽  
Author(s):  
A Shuster ◽  
EA Alexander ◽  
RC Lalone ◽  
NG Levinsky
Keyword(s):  
Blood Flow ◽  
Renal Blood Flow ◽  
Sodium Excretion ◽  
Saline Infusion

OS 06-04 CHANGES IN GENE EXPRESSION PATHWAYS PREDICT DELAYED SODIUM EXCRETION DURING SALINE INFUSION

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e62-e63
Author(s):  
Steven Hunt ◽  
Paul Hopkins ◽  
Nazeem Nanjee ◽  
Karen Schwander ◽  
Donald Kohan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sodium Excretion ◽  
Saline Infusion ◽  
Expression Pathways

A natriuretic factor is released by saline infusion into rat renal artery

1993 ◽  
Vol 264 (2) ◽  
pp. R268-R280
Author(s):  
E. M. Bullivant ◽  
D. J. Munoz
Keyword(s):  
Renal Artery ◽  
Sodium Excretion ◽  
Vena Cava ◽  
Sodium Concentration ◽  
Rat Plasma ◽  
Saline Infusion ◽  
Rapid Decline ◽  
Contralateral Kidney ◽  
Arterial Blood ◽  
Natriuretic Factor

Saline (154 mM NaCl) infused into one renal artery of anesthetized rats produced a prompt and substantial increase in sodium excretion without significant alteration of arterial pressure, renal blood flow, or glomerular filtration rate. A 1-h infusion at rates of 0.0375, 0.05, or 0.1 ml/min increased sodium excretion by the infused kidney from 0.15 +/- 0.04 to 0.70 +/- 0.12, from 0.45 +/- 0.10 to 2.17 +/- 0.40, and from 0.27 +/- 0.06 to 4.29 +/- 0.80 mumol/min, respectively. Natriuresis also occurred in the contralateral kidney. No comparable responses resulted from infusions at 0.0375 ml/min into the jugular vein, inferior vena cava, or carotid artery. Cross-circulation of blood from infused rats increased sodium excretion in uninfused recipients from 0.36 +/- 0.11 to 1.43 +/- 0.43 mumol.min-1.kidney-1. Isovolemic exchange-transfusion of blood from infused donor rats increased sodium excretion in uninfused recipients from 0.30 +/- 0.05 to 0.51 +/- 0.09 mumol.min-1.kidney-1. In both experiments, aortic infusions below the renal artery produced no comparable effect in recipient rats. Infusion of 300 mM glucose was not natriuretic. Infusion of two NaCl loads, 5.8 and 15.4 mumol/min, each at two different rates, increased sodium excretion in proportion to the load of NaCl and not to the rate of infusion. Infusions of a protein-free artificial rat plasma or of 140 mM NaCl, both with the sodium concentration of rat plasma, produced very little increase in sodium excretion. Infusion of 154 mM sodium lactate produced an increase in sodium excretion comparable to that produced by 154 mM NaCl. Reducing the infusion rate of 154 mM NaCl from 0.05 to 0.01 ml/min produced a rapid decline in the rate of sodium excretion. We conclude that renal arterial saline infusion activates a mechanism that increases sodium excretion by the infused kidney and concurrently causes the release of a natriuretic factor. Increased sodium concentration in renal arterial blood was the only stimulus found to produce the effect.

Angiotensin II in the renal excretory response to behavioral stress in conscious dogs

1983 ◽  
Vol 245 (2) ◽  
pp. R259-R264 ◽  
Author(s):  
J. P. Koepke ◽  
P. A. Obrist
Keyword(s):  
Sodium Excretion ◽  
Renin Angiotensin System ◽  
Urine Flow ◽  
Saline Infusion ◽  
Ang Ii ◽  
Water Excretion ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Behavioral Stress ◽  
Converting Enzyme Inhibition

The effects of inhibition of the renin-angiotensin system on the decreased renal excretion of sodium and water resulting from behavioral stress (shock avoidance) were examined in conscious saline-infused (4-5 ml/min) dogs. During saline infusion alone in six dogs, avoidance decreased sodium excretion (64% from 329 mueq/min) and urine flow (63% from 1.9 ml/min). During converting enzyme inhibition with captopril in the same dogs, the decreases in sodium excretion (35% from 464 mueq/min) and urine flow (35% from 2.6 ml/min) during avoidance were attenuated. Similarly, in six other dogs, avoidance decreased sodium excretion (41% from 361 mueq/min) and urine flow (43% from 2.1 ml/min) with saline infusion alone. During angiotension II (ANG II) receptor antagonism with saralasin, decreases in sodium excretion (29% from 417 mueq/min) and urine flow (27% from 2.2 ml/min) were attenuated. These mean changes in excretion during inhibition of the renin-angiotensin system were significantly (P less than 0.05) less than during saline alone. Whereas decreases in fractional sodium and water excretion were attenuated by renin-angiotensin inhibition, decreases in glomerular filtration rate and effective renal blood flow and increases in mean arterial pressure were not affected. These results indicate that ANG II contributes to the renal excretory response to avoidance.

The Effects of Rapid Saline Infusion on Sodium Excretion, Renal Function, and Blood Pressure at Different Sodium Intakes in Man

1983 ◽  
Vol 2 (4) ◽  
pp. 464-470 ◽  
Author(s):  
Friedrich C. Luft ◽  
Laura I. Rankin ◽  
Richard Bloch ◽  
Lynn R. Willis ◽  
Naomi S. Fineberq ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Sodium Excretion ◽  
Saline Infusion
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