Gestational Age-Specific Reference Ranges of Hepcidin in Cord Blood

Neonatology ◽  
2014 ◽  
Vol 106 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Laila Lorenz ◽  
Johanna Herbst ◽  
Corinna Engel ◽  
Andreas Peter ◽  
Harald Abele ◽  
...  
2006 ◽  
Vol 107 (1) ◽  
pp. 206
Author(s):  
Jodi S. Dashe ◽  
Brian M. Casey ◽  
Edward C. Wells ◽  
Donald D. McIntire ◽  
Kenneth J. Leveno ◽  
...  

2013 ◽  
Vol 41 (6) ◽  
pp. 649-652 ◽  
Author(s):  
P. DeKoninck ◽  
J. Deprest ◽  
P. Lewi ◽  
J. Richter ◽  
S. Galjaard ◽  
...  

2018 ◽  
Vol 31 (4) ◽  
pp. 435-441 ◽  
Author(s):  
Yuqi Yang ◽  
Bin Yu ◽  
Wei Long ◽  
Huaiyan Wang ◽  
Ying Wang ◽  
...  

AbstractBackground:The objective of the study was to investigate the changes in amino acid (AAs) values in premature infants.Methods:A total of 2159 premature and/or low birth weight infants were recruited for this study. They were divided into three groups: premature infants with normal birth weight (G1), simple low birth weight infants (G2) and premature combined with low birth weight infants (G3). The tandem mass spectrometry technique was used to detect the levels of 11 AAs in neonatal blood.Results:Compared with normal babies, there were eight and five AAs that significantly changed in G1 and G2, respectively. It was worth noting that the changes greatly exacerbated when the babies were both premature and of low birth weight. All the levels of AAs demonstrated significant changes in G3 compared with the normal control group (G4). With the increase in gestational age, the AAs in premature infants tended to the levels in normal newborns. Meanwhile, there was a correlation between AAs and birth weight. Four AAs significantly changed with the increase in body weight. Among normal newborns, the levels of AAs in girls were significantly higher than in boys. However, if the newborns were premature or had low birth weight, the differences between AA values and sexual distinction would decrease. In the end, we established the specific reference ranges of AAs for premature and/or low birth weight infants.Conclusions:There were significant differences in AAs in the premature and/or low birth weight infants. Gestational age and birth weight were two important factors inflecting the AAs metabolism.


2019 ◽  
Vol 54 (5) ◽  
pp. 670-675 ◽  
Author(s):  
H. Perry ◽  
O. Stirrup ◽  
J. Gutierrez ◽  
D. Vinayagam ◽  
B. Thilaganathan ◽  
...  

Neonatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Vincent D. Gaertner ◽  
Dirk Bassler ◽  
Roland Zimmermann ◽  
Jehudith R. Fontijn

<b><i>Introduction:</i></b> Umbilical artery cord blood provides information about the intrauterine metabolism during labor. Umbilical artery lactate is a useful parameter in predicting neonatal morbidity, but data on normal values are limited. We aimed to provide reference ranges of umbilical artery lactate values across the combination of gestational age and mode of delivery. <b><i>Methods:</i></b> A single-center retrospective observational study of liveborn infants born between 23 and 42 completed weeks gestation was conducted. Lactate, base deficit (BD), and pH from arterial cord blood were assessed between June 2018 and November 2020 and compared across gestational ages and modes of delivery. <b><i>Results:</i></b> Overall, there were 3,353 infants with evaluable data. Lactate values at the 50th, 90th, and 97th percentile were 3.4, 7.0, and 9.0 mmol/L. Lactate was inversely correlated with pH (<i>r</i> = −0.77, <i>p</i> &#x3c; 0.001) and positively correlated with BD (<i>r</i> = 0.63, <i>p</i> &#x3c; 0.001). Lactate values changed significantly across gestational age (Kruskal-Wallis test, <i>p</i> &#x3c; 0.001) which was attributable to an increase in lactate at 39–41 weeks gestational age. Also, lactate values were different across modes of delivery (Kruskal-Wallis test, <i>p</i> &#x3c; 0.001) with lowest values in elective CS and highest values in vaginal instrumental deliveries. Comprehensive reference ranges across modes of delivery and gestational ages could be established. <b><i>Discussion:</i></b> Mode of delivery and gestational age contribute to lactate levels with highest values occurring in vaginal instrumental deliveries and between 39 and 41 weeks gestational age. Based on these observations, we provide detailed reference ranges for clinical use.


2005 ◽  
Vol 106 (4) ◽  
pp. 753-757 ◽  
Author(s):  
Jodi S. Dashe ◽  
Brian M. Casey ◽  
C Edward Wells ◽  
Donald D. McIntire ◽  
E William Byrd ◽  
...  

2016 ◽  
Vol 6 (3) ◽  
pp. 165-166 ◽  
Author(s):  
Maria de la Calle ◽  
Juan L. Delgado ◽  
Stefan Verlohren ◽  
Ana Escudero ◽  
José l Bartha ◽  
...  

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