Gestational age-specific reference ranges for amniotic fluid assessment in monochorionic diamniotic twin pregnancies

2013 ◽  
Vol 41 (6) ◽  
pp. 649-652 ◽  
Author(s):  
P. DeKoninck ◽  
J. Deprest ◽  
P. Lewi ◽  
J. Richter ◽  
S. Galjaard ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Specific Reference ◽  
Reference Ranges ◽  
Fluid Assessment ◽  
Twin Pregnancies

Thyroid-Stimulating Hormone in Singleton and Twin Pregnancy: Importance of Gestational Age–Specific Reference Ranges

2006 ◽  
Vol 107 (1) ◽  
pp. 206
Author(s):  
Jodi S. Dashe ◽  
Brian M. Casey ◽  
Edward C. Wells ◽  
Donald D. McIntire ◽  
Kenneth J. Leveno ◽  
...  
Keyword(s):  
Gestational Age ◽  
Twin Pregnancy ◽  
Thyroid Stimulating Hormone ◽  
Specific Reference ◽  
Reference Ranges ◽  
Stimulating Hormone

Investigating the changes in amino acid values in premature infants: a pilot study

2018 ◽  
Vol 31 (4) ◽  
pp. 435-441 ◽  
Author(s):  
Yuqi Yang ◽  
Bin Yu ◽  
Wei Long ◽  
Huaiyan Wang ◽  
Ying Wang ◽  
...  
Keyword(s):  
Birth Weight ◽  
Amino Acid ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Gestational Age ◽  
Control Group ◽  
Specific Reference ◽  
Reference Ranges ◽  
Low Birth Weight Infants ◽  
Normal Birth

AbstractBackground:The objective of the study was to investigate the changes in amino acid (AAs) values in premature infants.Methods:A total of 2159 premature and/or low birth weight infants were recruited for this study. They were divided into three groups: premature infants with normal birth weight (G1), simple low birth weight infants (G2) and premature combined with low birth weight infants (G3). The tandem mass spectrometry technique was used to detect the levels of 11 AAs in neonatal blood.Results:Compared with normal babies, there were eight and five AAs that significantly changed in G1 and G2, respectively. It was worth noting that the changes greatly exacerbated when the babies were both premature and of low birth weight. All the levels of AAs demonstrated significant changes in G3 compared with the normal control group (G4). With the increase in gestational age, the AAs in premature infants tended to the levels in normal newborns. Meanwhile, there was a correlation between AAs and birth weight. Four AAs significantly changed with the increase in body weight. Among normal newborns, the levels of AAs in girls were significantly higher than in boys. However, if the newborns were premature or had low birth weight, the differences between AA values and sexual distinction would decrease. In the end, we established the specific reference ranges of AAs for premature and/or low birth weight infants.Conclusions:There were significant differences in AAs in the premature and/or low birth weight infants. Gestational age and birth weight were two important factors inflecting the AAs metabolism.

Gestational Age-Specific Reference Ranges of Hepcidin in Cord Blood

Neonatology ◽  
2014 ◽  
Vol 106 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Laila Lorenz ◽  
Johanna Herbst ◽  
Corinna Engel ◽  
Andreas Peter ◽  
Harald Abele ◽  
...  
Keyword(s):  
Cord Blood ◽  
Gestational Age ◽  
Specific Reference ◽  
Reference Ranges

scholarly journals Influence of maternal characteristics and gestational age on hemodynamic indices: NICOM device‐specific reference ranges

2019 ◽  
Vol 54 (5) ◽  
pp. 670-675 ◽  
Author(s):  
H. Perry ◽  
O. Stirrup ◽  
J. Gutierrez ◽  
D. Vinayagam ◽  
B. Thilaganathan ◽  
...  
Keyword(s):  
Gestational Age ◽  
Specific Reference ◽  
Reference Ranges ◽  
Maternal Characteristics

scholarly journals Gestational Age-Specific Reference Ranges for the sFlt-1/PlGF Immunoassay Ratio in Twin Pregnancies

2021 ◽  
pp. 1-9
Author(s):  
Maria De La Calle ◽  
Juan L. Delgado ◽  
Stefan Verlohren ◽  
Ana Isabel Escudero ◽  
Jose L. Bartha ◽  
...  
Keyword(s):  
Specific Reference ◽  
Reference Ranges ◽  
Range Analysis ◽  
Short Term ◽  
Term Outcome ◽  
Twin Pregnancies ◽  
Plgf Ratio ◽  
Control Study ◽  
Normal Twin ◽  
Singleton Pregnancies

<b><i>Objective:</i></b> Establish reference ranges for the Elecsys® soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF) immunoassay ratio in twin pregnancies. <b><i>Methods:</i></b> Data analyzed were from 3 prospective studies: Prediction of Short-Term Outcome in Pregnant Women with Suspected Preeclampsia (PE) (PROGNOSIS), Study of Early-onset PE in Spain (STEPS), and a multicenter case-control study. Median, 5th, and 95th percentiles for sFlt-1, PlGF, and the sFlt-1/PlGF ratios were determined for normal twin pregnancies for 7 gestational windows and compared with the previous data for singleton pregnancies. <b><i>Results:</i></b> The reference range analysis included 269 women with normal twin pregnancies. Before 29 weeks’ gestation, median, 5th, and 95th percentiles for sFlt-1/PlGF ratios did not differ between twin and singleton pregnancies. From 29 weeks’ gestation to delivery, median, 5th, and 95th percentiles for sFlt-1/PlGF ratios were substantially higher in twin versus singleton pregnancies. sFlt-1 values were higher in women with twin pregnancies across all gestational windows. PlGF values were similar or higher in twin versus singleton pregnancies; PlGF concentrations increased from 10 weeks + 0 days to 28 weeks + 6 days’ gestation. <b><i>Conclusions:</i></b> Reference ranges for the sFlt-1/PlGF ratio are similar in women with twin and singleton pregnancies until 29 weeks’ gestation but appear higher in twin pregnancies thereafter.

Thyroid-Stimulating Hormone in Singleton and Twin Pregnancy: Importance of Gestational Age–Specific Reference Ranges

2005 ◽  
Vol 106 (4) ◽  
pp. 753-757 ◽  
Author(s):  
Jodi S. Dashe ◽  
Brian M. Casey ◽  
C Edward Wells ◽  
Donald D. McIntire ◽  
E William Byrd ◽  
...  
Keyword(s):  
Gestational Age ◽  
Twin Pregnancy ◽  
Thyroid Stimulating Hormone ◽  
Specific Reference ◽  
Reference Ranges ◽  
Stimulating Hormone

scholarly journals Reference Ranges of Amniotic Fluid Index in Late Third Trimester of Pregnancy: What Should the Optimal Interval between Two Ultrasound Examinations Be?

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Shripad Hebbar ◽  
Lavanya Rai ◽  
Prashant Adiga ◽  
Shyamala Guruvare
Keyword(s):  
Diabetes Mellitus ◽  
Amniotic Fluid ◽  
Gestational Age ◽  
Local Population ◽  
Low Risk ◽  
Reference Ranges ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Percentile Curves ◽  
Biophysical Profile

Background. Amniotic fluid index (AFI) is one of the major and deciding components of fetal biophysical profile and by itself it can predict pregnancy outcome. Very low values are associated with intrauterine growth restriction and renal anomalies of fetus, whereas high values may indicate fetal GI anomalies, maternal diabetes mellitus, and so forth. However, before deciding the cut-off standards for abnormal values for a local population, what constitutes a normal range for specific gestational age and the ideal interval of testing should be defined.Objectives. To establish reference standards for AFI for local population after 34 weeks of pregnancy and to decide an optimal scan interval for AFI estimation in third trimester in low risk antenatal women.Materials and Methods. A prospective estimation of AFI was done in 50 healthy pregnant women from 34 to 40 weeks at weekly intervals. The trend of amniotic fluid volume was studied with advancing gestational age. Only low risk singleton pregnancies with accurately established gestational age who were available for all weekly scan from 34 to 40 weeks were included in the study. Women with gestational or overt diabetes mellitus, hypertensive disorders of the pregnancy, prelabour rupture of membranes, and congenital anomalies in the foetus and those who delivered before 40 completed weeks were excluded from the study. For the purpose of AFI measurement, the uterine cavity was arbitrarily divided into four quadrants by a vertical and horizontal line running through umbilicus. Linear array transabdominal probe was used to measure the largest vertical pocket (in cm) in perpendicular plane to the abdominal skin in each quadrant. Amniotic fluid index was obtained by adding these four measurements. Statistical analysis was done using SPSS software (Version 16, Chicago, IL). Percentile curves (5th, 50th, and 95th centiles) were constructed for comparison with other studies. Cohen’sdcoefficient was used to examine the magnitude of change at different time intervals.Results. Starting from 34 weeks till 40 weeks, 50 ultrasound measurements were available at each gestational age. The mean (standard deviation) of AFI values (in cms) were 34 W: 14.59 (1.79), 35 W: 14.25 (1.57), 36 W: 13.17 (1.56), 37 W: 12.48 (1.52), 38 W: 12.2 (1.7), and 39 W: 11.37 (1.71). The 5th percentile cut-off was 8.7 cm at 40 weeks. There was a gradual decline of AFI values as the gestational age approached term. Significant drop in AFI was noted at two-week intervals. AFI curve generated from the study varied significantly when compared with already published data, both from India and abroad.Conclusion. Normative range for AFI values for late third trimester was established. Appreciable changes occurred in AFI values as gestation advanced by two weeks. Hence, it is recommended to follow up low risk antenatal women every two weeks after 34 weeks of pregnancy. The percentile curves of AFI obtained from the present study may be used to detect abnormalities of amniotic fluid for our population.

scholarly journals Placenta Morphological and Amniotic Fluid Biochemical Changes Associated with Mid-Gestation Single and Twin Pregnancies in Red Sokoto Goats

2021 ◽  
Vol 10 (1) ◽  
pp. 8-12
Keyword(s):  
Amniotic Fluid ◽  
Gestational Age ◽  
Total Protein ◽  
Biochemical Changes ◽  
Uterine Weight ◽  
Optimal Conditions ◽  
Crown Rump Length ◽  
Liver Markers ◽  
Twin Pregnancies ◽  
Fetal Fluids

Fetal fluids and placentas, which are important in feto-maternal homeostasis, could be affected by the number of developing fetuses. Therefore, placenta morphological and amniotic fluid biochemical changes associated with single and twin pregnancies in Red Sokoto goats were studied. Using Richardson’s formula, 2.1 × [CRL (cm) + 17], 12 intact gravid uteri (7 single-pregnant and 5 twin-pregnant) from mid-gestation [≈70-100 days gestational age (dGA)] pregnant goats were purposively selected. Feto-maternal biometrics [gravid uterine weight (GUW), total placental fluid volume (TPFV), average placentome diameter (APD), mean crown-rump length (MCRL), mean gestational age (MGA), mean fetal weight (MFW), total placentome number (TPN), and average interplacentomal distance (AID)]; amniotic fluid electrolytes [sodium (Na), potassium (K), chloride (Cl), calcium (Ca) and phosphorus (P)]; total protein; glucose; liver markers (AST and ALT); kidney markers (urea and creatinine), and cortisol concentrations were measured. The histology of the placentomes and the interplacentomal areas was also studied. The twin-pregnant (TP) goats had significantly higher (P<0.05) GUW, TPFV, APD, amniotic fluid glucose and cortisol; and lower (P<0.05) Ca levels. The rest of the parameters assessed did not differ between the TP and single-pregnant (SP) groups. Placentomes and the interplacentomal areas from the TP group had more diffuse villous inter-digitations and thicker luminal endothelium, respectively. It was concluded that TP Red Sokoto goats regulated placentome morphology, calcium, glucose and cortisol levels in order to achieve optimal conditions for the dams and the fetuses.

59 Gestational age-specific reference ranges for the sFlt-1/PlGF ratio in multiple pregnancies

2016 ◽  
Vol 6 (3) ◽  
pp. 165-166 ◽  
Author(s):  
Maria de la Calle ◽  
Juan L. Delgado ◽  
Stefan Verlohren ◽  
Ana Escudero ◽  
José l Bartha ◽  
...  
Keyword(s):  
Gestational Age ◽  
Specific Reference ◽  
Reference Ranges ◽  
Multiple Pregnancies ◽  
Plgf Ratio
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