scholarly journals In vivo Tissue Engineering: Mimicry of Homing Factors for Self-Endothelialization of Blood-Contacting Materials

Pathobiology ◽  
2013 ◽  
Vol 80 (4) ◽  
pp. 176-181 ◽  
Author(s):  
Meltem Avci-Adali ◽  
Heidi Stoll ◽  
Nadja Wilhelm ◽  
Nadja Perle ◽  
Christian Schlensak ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
In Vivo Tissue Engineering

The use of pimonidazole to characterise hypoxia in the internal environment of an in vivo tissue engineering chamber

2005 ◽  
Vol 58 (8) ◽  
pp. 1104-1114 ◽  
Author(s):  
S.O.P. Hofer ◽  
G.M. Mitchell ◽  
A.J. Penington ◽  
W.A. Morrison ◽  
R. RomeoMeeuw ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Internal Environment ◽  
In Vivo Tissue Engineering

scholarly journals The Arteriovenous Loop: Engineering of Axially Vascularized Tissue

2018 ◽  
Vol 59 (3-4) ◽  
pp. 286-299 ◽  
Author(s):  
Annika Weigand ◽  
Raymund E. Horch ◽  
Anja M. Boos ◽  
Justus P. Beier ◽  
Andreas Arkudas
Keyword(s):  
Tissue Engineering ◽  
Large Scale ◽  
Treatment Options ◽  
Current Treatment ◽  
Loop Model ◽  
Engineering Approach ◽  
In Vivo Tissue Engineering ◽  
Tissue Engineering Approach ◽  
Tissue Defects

Background: Most of the current treatment options for large-scale tissue defects represent a serious burden for the patients, are often not satisfying, and can be associated with significant side effects. Although major achievements have already been made in the field of tissue engineering, the clinical translation in case of extensive tissue defects is only in its early stages. The main challenge and reason for the failure of most tissue engineering approaches is the missing vascularization within large-scale transplants. Summary: The arteriovenous (AV) loop model is an in vivo tissue engineering strategy for generating axially vascularized tissues using the own body as a bioreactor. A superficial artery and vein are anastomosed to create an AV loop. This AV loop is placed into an implantation chamber for prevascularization of the chamber inside, e.g., a scaffold, cells, and growth factors. Subsequently, the generated tissue can be transplanted with its vascular axis into the defect site and anastomosed to the local vasculature. Since the blood supply of the growing tissue is based on the AV loop, it will be immediately perfused with blood in the recipient site leading to optimal healing conditions even in the case of poorly vascularized defects. Using this tissue engineering approach, a multitude of different axially vascularized tissues could be generated, such as bone, skeletal or heart muscle, or lymphatic tissues. Upscaling from the small animal AV loop model into a preclinical large animal model could pave the way for the first successful attempt in clinical application. Key Messages: The AV loop model is a powerful tool for the generation of different axially vascularized replacement tissues. Due to minimal donor site morbidity and the possibility to generate patient-specific tissues variable in type and size, this in vivo tissue engineering approach can be considered as a promising alternative therapy to current treatment options of large-scale defects.

Reconstructing Box-Like Bone Defect of Mandible with In Vivo Tissue Engineering Bone

2007 ◽  
pp. 1165-1168
Author(s):  
Jin Feng Yao ◽  
Y.Z. Zhang ◽  
C.Y. Bao ◽  
L.Y. Sun ◽  
X.M. Hao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Defect ◽  
In Vivo Tissue Engineering

scholarly journals Adipose-Derived Stem Cells Promote Angiogenesis and Tissue Formation for In Vivo Tissue Engineering

2013 ◽  
Vol 19 (11-12) ◽  
pp. 1327-1335 ◽  
Author(s):  
Ken Matsuda ◽  
Katrina J. Falkenberg ◽  
Alan A. Woods ◽  
Yu Suk Choi ◽  
Wayne A. Morrison ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Adipose Derived Stem Cells ◽  
Tissue Formation ◽  
In Vivo Tissue Engineering

Nanocomposite injectable gels capable of self-replenishing regenerative extracellular microenvironments for in vivo tissue engineering

2018 ◽  
Vol 6 (3) ◽  
pp. 550-561 ◽  
Author(s):  
Koji Nagahama ◽  
Naho Oyama ◽  
Kimika Ono ◽  
Atsushi Hotta ◽  
Keiko Kawauchi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Building Blocks ◽  
The Body ◽  
Bioactive Molecules ◽  
In Vivo Tissue Engineering ◽  
Injectable Gels

Nanocomposite injectable gels, which self-replenish regenerative extracellular microenvironments within the gels in the body by utilizing host-derived bioactive molecules as building blocks, are reported.

Neohybrid Liver Graft - a Novel Concept of in Vivo Tissue-Engineering

2012 ◽  
Vol 94 (10S) ◽  
pp. 336
Author(s):  
S. Rohn ◽  
M. T. Mogl ◽  
H. Riedel ◽  
J. Schroeder ◽  
N. Billecke ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Liver Graft ◽  
In Vivo Tissue Engineering ◽  
Novel Concept

scholarly journals In Vivo Tissue Engineering of Human Airways

2017 ◽  
Vol 103 (5) ◽  
pp. 1631-1640 ◽  
Author(s):  
Emmanuel Martinod ◽  
Joseph Paquet ◽  
Hervé Dutau ◽  
Dana M. Radu ◽  
Morad Bensidhoum ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
In Vivo Tissue Engineering ◽  
Human Airways

IN VIVO TISSUE ENGINEERING OF THE COMMON BILE DUCT USING SMALL INTESTINAL SUBMUCOSA IN A CANINE MODEL

ASAIO Journal ◽  
2002 ◽  
Vol 48 (2) ◽  
pp. 197
Author(s):  
Dai Kimura ◽  
Tatsuo Nakamura ◽  
Kenji Kaino ◽  
Yoshio Hori ◽  
Masaki Nio ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Canine Model ◽  
Small Intestinal Submucosa ◽  
In Vivo Tissue Engineering ◽  
The Common ◽  
Small Intestinal ◽  
Intestinal Submucosa
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