A Comparison of in vitro Culture of Fetal Nucleated Erythroblasts from Fetal Chorionic Villi and Maternal Peripheral Blood for Noninvasive Prenatal Diagnosis

2012 ◽  
Vol 32 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Shengxia Zheng ◽  
Xianhong Tong ◽  
Limin Wu ◽  
Guoping He ◽  
Bangsheng Ding ◽  
...  
2022 ◽  
Vol 2022 ◽  
pp. 1-8
Author(s):  
Ying Tang ◽  
Qiaojin Tang ◽  
Haiyan Luo ◽  
Xuehui Zhang ◽  
Qiuyu Chen ◽  
...  

Prenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity and high-accuracy prenatal diagnosis technology. However, the number of fetal cells is small and it is difficult to apply clinically. In recent years, noninvasive prenatal diagnosis (NIPD) technology for fetal genetic material in maternal peripheral blood has developed rapidly, which makes it possible to diagnose genetic diseases by fetal cells in maternal peripheral blood. This article reviewed the current status of fetal cell separation and enrichment technology and its application in noninvasive prenatal diagnosis technology.


1992 ◽  
Vol 12 (6) ◽  
pp. 547-548 ◽  
Author(s):  
Y.-M. D. Lo ◽  
J. S. Wainscoat ◽  
K. A. Fleming

1997 ◽  
Vol 39 (1) ◽  
pp. 55-63
Author(s):  
Yoshinobu Shimizu ◽  
Hiroko Sugawara ◽  
Yoshiyuki Shimizu ◽  
Mirei Miki ◽  
Satoshi Abe ◽  
...  

1996 ◽  
Vol 39 (4) ◽  
pp. 801-813 ◽  
Author(s):  
C. DANAE STEELE ◽  
RONALD J. WAPNER ◽  
J. BRUCE SMITH ◽  
MARK K. HAYNES ◽  
LAIRD G. JACKSON

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