The Occurrence of Degeneration Phenomena during the Process of Separation of the Primitive Ureter from the Wolffian Duct

1959 ◽  
Vol 8 (2-3) ◽  
pp. 117-125
Author(s):  
Stig Bengmark
Keyword(s):  
Wolffian Duct

Epididymal Cyst - A Case Study

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr. Vinayak A. Mali ◽  
Dr.Prashanth K.
Keyword(s):  
Local Anaesthesia ◽  
Marked Improvement ◽  
Wolffian Duct ◽  
Cystic Degeneration ◽  
Mullerian Duct ◽  
Duct System ◽  
Middle Aged ◽  
Müllerian Duct ◽  
Mesonephric Duct

Cysts of the epididymis are usually congenital and derived from an embryonic remnant. These cysts are due to cystic degeneration of remnants of the paramesonephric or Mullerian duct and Remnants of the mesonephric duct or Wolffian duct system. Here we report a case of bilateral Epididymal cysts in a middle aged man with a complaint of scrotal lump and infertility since 15 years. He was treated with excision of the cysts under local anaesthesia and had a marked improvement in scrotal discomfort and urgency of micturition after the treatment.

Paravaginal Wolffian Duct (Mesonephros) Adenocarcinoma: A Light and Electron Microscopic Study

1983 ◽  
Vol 80 (4) ◽  
pp. 539-544 ◽  
Author(s):  
William W. Hinchey ◽  
Elvio G. Silva ◽  
Luis A. Guarda ◽  
Nelson G. Ordonez ◽  
J. Taylor Wharton
Keyword(s):  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Wolffian Duct ◽  
Electron Microscopic

Role of Ca2+ in the IVM of spermatozoa from the sterlet Acipenser ruthenus

2017 ◽  
Vol 29 (7) ◽  
pp. 1319 ◽  
Author(s):  
Olga Bondarenko ◽  
Borys Dzyuba ◽  
Marek Rodina ◽  
Jacky Cosson
Keyword(s):  
Sperm Motility ◽  
Seminal Fluid ◽  
Mature Male ◽  
Sperm Maturation ◽  
Wolffian Duct ◽  
Testicular Spermatozoa ◽  
Acipenser Ruthenus ◽  
Sterlet Acipenser Ruthenus ◽  
Motility Parameters

The role of Ca2+ in sturgeon sperm maturation and motility was investigated. Sperm from mature male sterlets (Acipenser ruthenus) were collected from the Wolffian duct and testis 24 h after hormone induction. Testicular spermatozoa (TS) were incubated in Wolffian duct seminal fluid (WDSF) for 5 min at 20°C and were designated ‘TS after IVM’ (TSM). Sperm motility was activated in media with different ion compositions, with motility parameters analysed from standard video microscopy records. To investigate the role of calcium transport in the IVM process, IVM was performed (5 min at 20°C) in the presence of 2 mM EGTA, 100 µM Verapamil or 100 µM Tetracaine. No motility was observed in the case of TS (10 mM Tris, 25 mM NaCl, 50 mM Sucr with or without the addition of 2 mM EGTA). Both incubation of TS in WDSF and supplementation of the activation medium with Ca2+ led to sperm motility. The minimal Ca2+ concentration required for motility activation of Wolffian duct spermatozoa, TS and TSM was determined (1–2 nM for Wolffian duct spermatozoa and TSM; approximately 0.6 mM for TS). Motility was obtained after the addition of verapamil to the incubation medium during IVM, whereas the addition of EGTA completely suppressed motility, implying Ca2+ involvement in sturgeon sperm maturation. Further studies into the roles of Ca2+ transport in sturgeon sperm maturation and motility are required.

Wolffian Duct Development

2014 ◽  
Vol 8 (5) ◽  
pp. 273-280 ◽  
Author(s):  
Geoffrey Shaw ◽  
Marilyn B. Renfree
Keyword(s):  
Wolffian Duct ◽  
Duct Development

scholarly journals Radiological Manifestations of Obstructed Hemivagina and Ipsilateral Renal Anomaly Syndrome: A Rare Complex Müllerian and Wolffian Duct Anomaly

2016 ◽  
Vol 02 (01) ◽  
pp. 033-039
Author(s):  
Tushar Patil ◽  
Devarati Khurjekar ◽  
Vikash Ojha
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Pelvic Pain ◽  
Wolffian Duct ◽  
Resonance Imaging ◽  
Renal Anomalies ◽  
Renal Anomaly ◽  
Ohvira Syndrome ◽  
Obstructed Hemivagina ◽  
Magnetic Resonance Imaging Mri

AbstractObstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare complex Müllerian and Wolffian duct anomaly. It is also known as Herlyn–Werner–Wunderlich syndrome (HWWS). It includes unilateral renal anomalies and uterine didelphys. It generally occurs at puberty and exhibits non-specific and variable symptoms with acute or pelvic pain shortly following menarche, causing a delay in the diagnosis. We report here a 16-year-old female presenting with progressive cyclical pelvic pain, where magnetic resonance imaging (MRI) suggested the diagnosis of the OHVIRA syndrome. She was managed by surgical resection of the septum and draining of the obstructed vagina.

scholarly journals X. On the existence of a rudimentary head-kidney in the embryo chick

1878 ◽  
Vol 27 (185-189) ◽  
pp. 443-446 ◽  
Keyword(s):  
Head Kidney ◽  
Wolffian Duct ◽  
Germinal Epithelium ◽  
Mullerian Duct ◽  
Short Account ◽  
Müllerian Duct ◽  
Front End ◽  
Wolffian Body ◽  
Embryo Chick ◽  
Shallow Groove

We have been for some time engaged in an investigation on the mode of growth of the developing Müllerian duct in the chick, and its possible derivation from the Wolffian duct; and, while carrying on our investigations on this point, were struck by some remarkable features of the abdominal opening of the Müllerian duct in its very early condition. We did not for some time pay much attention to these features, but finally devoted ourselves to their interpretation, and have been led to the conclusion that they form the rudiment of a head-kidney, “Vomiere” or “Kopfniere,” identical with that present in Amphibia, Marsipobranchii, and Teleostei. We purpose first to give a short account of our observations,, and then to proceed to state the grounds on which we have been led to compare the structures we have found with the head-kidney of the Ichthyopsida The first trace of the Müllerian duct we have met with is a very shallow groove in the germinal epithelium some little way behind the front end of the Wolffian body, and nearly overlying, though slightly external to, the Wolffian duct. This stage corresponds with the earliest stage described by Dr. Gasser. In the next stage, which follows very closely upon the first one, remarkable changes have taken place in the groove, which can best be explained by describing the appearance of a series of successive sections from before backwards through the groove and its continuation.

Induction of functional cytodifferentiation in the epithelium of tissue recombinants. II. Instructive induction of Wolffian duct epithelia by neonatal seminal vesicle mesenchyme

Development ◽  
1989 ◽  
Vol 106 (2) ◽  
pp. 235-250 ◽  
Author(s):  
S.J. Higgins ◽  
P. Young ◽  
G.R. Cunha
Keyword(s):  
Seminal Vesicle ◽  
Normal Development ◽  
Seminal Vesicles ◽  
Wolffian Duct ◽  
Secretory Proteins ◽  
Ductus Deferens ◽  
Tissue Sections ◽  
Duct Epithelium ◽  
Mouse Tissues ◽  
Renal Grafts

When grown as renal grafts in adult male hosts, the upper (cranial), middle and lower (caudal) portions of fetal mouse and rat Wolffian ducts developed into epididymis, epididymis plus ductus deferens, and seminal vesicle, respectively. In heterotypic tissue recombinants, the epithelia from upper and middle Wolffian ducts were instructively induced to undergo seminal vesicle morphogenesis by neonatal seminal vesicle mesenchyme. Functional cytodifferentiation was examined in these recombinants using antibodies against major androgen-dependent, seminal vesicle-specific secretory proteins. The instructively induced Wolffian duct epithelia synthesized normal amounts of all of the secretory proteins characteristic of mature seminal vesicles, as judged by immunocytochemistry on tissue sections and gel electrophoresis plus immunoblotting of secretions extracted from the recombinants. In heterospecific recombinants composed of rat and mouse tissues, the seminal vesicle proteins induced were specific for the species that had provided the epithelium. This showed that the seminal vesicle epithelium in the recombinants was derived from instructively induced Wolffian duct epithelium and not from epithelial contamination of the mesenchymal inductor. Upper Wolffian duct epithelium, instructively induced to undergo seminal vesicle morphogenesis, did not express epididymis-specific secretory proteins, showing that its normal development had been simultaneously repressed.

scholarly journals Images – A series of congenital mesonephric/Wolffian duct abnormalities in the adult and pediatric populations

2020 ◽  
Vol 14 (11) ◽  
Author(s):  
Meghan Cooper ◽  
Calvin Guiterrez ◽  
Hubert Swana ◽  
Mark Rich ◽  
Lucas Wiegand
Keyword(s):  
Wolffian Duct ◽  
Pediatric Populations

Pkd1-targeted mutation reveals a role for the Wolffian duct in autosomal dominant polycystic kidney disease

2019 ◽  
Vol 11 (1) ◽  
pp. 78-85 ◽  
Author(s):  
J. B. Tee ◽  
A. V. Dnyanmote ◽  
M. K. Lorenzo ◽  
O. R. Lee ◽  
S. Grisaru ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
High Throughput Sequencing ◽  
Autosomal Dominant ◽  
Cyst Formation ◽  
Wolffian Duct ◽  
Renal Tubules ◽  
Polycystic Kidney ◽  
Cystic Kidneys ◽  
Autosomal Dominant Polycystic Kidney

AbstractSeveral life-threatening diseases of the kidney have their origins in mutational events that occur during embryonic development. In this study, we investigate the role of the Wolffian duct (WD), the earliest embryonic epithelial progenitor of renal tubules, in the etiology of autosomal dominant polycystic kidney disease (ADPKD). ADPKD is associated with a germline mutation of one of the two Pkd1 alleles. For the disease to occur, a second event that disrupts the expression of the other inherited Pkd1 allele must occur. We postulated that this secondary event can occur in the pronephric WD. Using Cre-Lox recombination, mice with WD-specific deletion of one or both Pkd1 alleles were generated. Homozygous Pkd1-targeted deletion in WD-derived tissues resulted in mice with large cystic kidneys and serologic evidence of renal failure. In contrast, heterozygous deletion of Pkd1 in the WD led to kidneys that were phenotypically indistinguishable from control in the early postnatal period. High-throughput sequencing, however, revealed underlying gene and microRNA (miRNA) changes in these heterozygous mutant kidneys that suggest a strong predisposition toward developing ADPKD. Bioinformatic analysis of this data demonstrated an upregulation of several miRNAs that have been previously associated with PKD; pathway analysis further demonstrated that the differentially expressed genes in the heterozygous mutant kidneys were overrepresented in signaling pathways associated with maintenance and function of the renal tubular epithelium. These results suggest that the WD may be an early epithelial target for the genetic or molecular signals that can lead to cyst formation in ADPKD.

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