Vasoactive Intestinal Polypeptide(VIP)-Immunoreactive Nerve Fibers in the Anterior Uvea of the Guinea Pig

1985 ◽  
Vol 17 (4) ◽  
pp. 235-240 ◽  
Author(s):  
Hannu Uusitalo ◽  
Juha I. Lehtosalo ◽  
Arto Palkama
Keyword(s):  
Guinea Pig ◽  
Vasoactive Intestinal Polypeptide ◽  
Nerve Fibers ◽  
Anterior Uvea ◽  
Intestinal Polypeptide

Vasodilator action of guinea pig vasoactive intestinal polypeptide (VIP): comparison with common mammalian VIP

1992 ◽  
Vol 42 (3) ◽  
pp. 163-171 ◽  
Author(s):  
Satoru Naruse ◽  
Takashi Inoue ◽  
Tohru Mochizuki ◽  
Noboru Yanaihara
Keyword(s):  
Guinea Pig ◽  
Vasoactive Intestinal Polypeptide ◽  
Vasodilator Action ◽  
Intestinal Polypeptide

scholarly journals A Light and Electron Microscopic Immunohistochemical Study of Vasoactive Intestinal Polypeptide— And Substance P-Containing Nerve Fibers along the Cerebral Blood Vessels: Comparison with Aminergic and Cholinergic Nerve Fibers

1984 ◽  
Vol 4 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Toru Itakura ◽  
Takashi Okuno ◽  
Kazuo Nakakita ◽  
Ichiro Kamei ◽  
Yutaka Naka ◽  
...  
Keyword(s):  
Substance P ◽  
Blood Vessels ◽  
Vasoactive Intestinal Polypeptide ◽  
Electron Microscopic Observation ◽  
Nerve Fibers ◽  
Muscle Control ◽  
Cerebral Blood Vessels ◽  
Electron Microscopic ◽  
Cholinergic Nerve Fibers ◽  
Intestinal Polypeptide

Vasoactive intestinal polypeptide (VIP)– and substance P–containing nerve fibers were observed in the cerebral blood vessels using an immunohistochemical technique. VIP-containing nerve fibers distributed in a spiral pattern, similar to that of muscle cells. Under electron microscopic observation, VIP-immunoreactive terminals lay close to a muscle cell in the inner layer of the adventitia. In contrast, substance P–containing nerve fibers showed a meshwork pattern in the outer layer of the adventitia. Using both acetylcholinesterase (AChE) staining and VIP immunohistochemistry, AChE-positive and VIP-immunoreactive nerve fibers revealed almost the same distribution in the same specimen. The present data suggest that VIP-containing nerve fibers may play a role in the smooth muscle control of the blood vessels, whereas substance P–containing nerve fibers may not take part in muscle control.

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