Effect of NaF and SnF2in Drinking Water on Hamster Dental Caries (Short Communication)

1984 ◽  
Vol 18 (1) ◽  
pp. 71-73 ◽  
Author(s):  
N. Tinanoff ◽  
D.A. Camosci
Keyword(s):  
Drinking Water ◽  
Dental Caries ◽  
Short Communication

Assessment of the drinking water quality for planning endogenic prevention of dental caries

2021 ◽  
Vol 21 (2) ◽  
pp. 88-93
Author(s):  
A. B. Shashmurina ◽  
O. L. Mishutina ◽  
V. R. Shashmurina
Keyword(s):  
Drinking Water ◽  
Dental Caries ◽  
Water Supply ◽  
Fluoride Concentration ◽  
Water Hardness ◽  
Drinking Water Supply ◽  
Ion Concentration ◽  
Normal Range ◽  
Hydrogen Ion Concentration ◽  
Normal Limits

Relevance. Dental caries is a leading dental disease in children. Aim – to study the quality of drinking water in Smolensk and its region to provide evidence for implementing dental caries preventive measures in children.Materials and methods. We took tap water samples from ten water intake points in seven districts of Smolensk and six Smolensk regions. An accredited testing laboratory of the Center for Hygiene and Epidemiology in the Smolensk Region carried out water chemical analysis. The study analyzed standard parameters of drinking water quality: pH 6.5-8.5, fluoride content 0.60-1.2 mg/l; water hardness 7.0-9.0 (Sanitary Regulations and Standards 2.1.4.1116-02). The parameter was considered normal if its 95% confidence interval was within the reference range.Results. In Smolensk, the hydrogen ion concentration in centralized drinking water supply systems is within normal limits and amounts to 7.39 (95% CI: 7.32-7.46; р < 0,05) pH units. The mean fluoride concentration in the Smolensk water is 0.19 (95% CI: 0.14-0.23; р < 0,05) mg/l, which is below the normal range. In most Smolensk districts, water hardness is within normal limits, 8.21 mmol/l (95% CI: 7.03-9.39; р < 0,05). However, the upper limit of the confidence interval of 9.39 mg/l and the maximum of 12.0 mg/l exceed the normal range. In the Smolensk region cities, the hydrogen ion concentration is 7.2 (95% CI: 7.02-7.38; р < 0,05) pH units in the centralized drinking water supply. The fluoride concentration in the Smolensk region water is 0.45 mg/l (95% CI: 0.23-0.68; р < 0,05), which demonstrates the fluoride deficiency in water. In the Smolensk region cities, mean water hardness is 6.66 mmol/l (95% CI: 6.00-7.03; р < 0,05), which is below the normal values. However, the CI upper limit of 7.03 mmol/l and the maximum of 7.05 mmol/l are within normal limits.Conclusions. The water of the centralized drinking water supply system in Smolensk and the Smolensk region is low in fluorides. Urgent community and individual preventive measures should be taken to expose children to fluoride.

scholarly journals Fluoride Depletes Acidogenic Taxa in Oral but Not Gut Microbial Communities in Mice

mSystems ◽  
2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Koji Yasuda ◽  
Tiffany Hsu ◽  
Carey A. Gallini ◽  
Lauren J. Mclver ◽  
Emma Schwager ◽  
...  
Keyword(s):  
Drinking Water ◽  
Dental Caries ◽  
Microbial Communities ◽  
Energy Harvest ◽  
Controlled Study ◽  
Human Consumption ◽  
Cross Sectional ◽  
Fluoride Treatment ◽  
Fluoride Exposure ◽  
Dental Products

ABSTRACT Fluoride has been added to drinking water and dental products since the 1950s. The beneficial effects of fluoride on oral health are due to its ability to inhibit the growth of bacteria that cause dental caries. Despite widespread human consumption of fluoride, there have been only two studies of humans that considered the effect of fluoride on human-associated microbial communities, which are increasingly understood to play important roles in health and disease. Notably, neither of these studies included a true cross-sectional control lacking fluoride exposure, as study subjects continued baseline fluoride treatment in their daily dental hygiene routines. To our knowledge, this work (in mice) is the first controlled study to assess the independent effects of fluoride exposure on the oral and gut microbial communities. Investigating how fluoride interacts with host-associated microbial communities in this controlled setting represents an effort toward understanding how common environmental exposures may potentially influence health. Fluoridation of drinking water and dental products prevents dental caries primarily by inhibiting energy harvest in oral cariogenic bacteria (such as Streptococcus mutans and Streptococcus sanguinis), thus leading to their depletion. However, the extent to which oral and gut microbial communities are affected by host fluoride exposure has been underexplored. In this study, we modeled human fluoride exposures to municipal water and dental products by treating mice with low or high levels of fluoride over a 12-week period. We then used 16S rRNA gene amplicon and shotgun metagenomic sequencing to assess fluoride’s effects on oral and gut microbiome composition and function. In both the low- and high-fluoride groups, several operational taxonomic units (OTUs) belonging to acidogenic bacterial genera (such as Parabacteroides, Bacteroides, and Bilophila) were depleted in the oral community. In addition, fluoride-associated changes in oral community composition resulted in depletion of gene families involved in central carbon metabolism and energy harvest (2-oxoglutarate ferredoxin oxidoreductase, succinate dehydrogenase, and the glyoxylate cycle). In contrast, fluoride treatment did not induce a significant shift in gut microbial community composition or function in our mouse model, possibly due to absorption in the upper gastrointestinal tract. Fluoride-associated perturbations thus appeared to have a selective effect on the composition of the oral but not gut microbial community in mice. Future studies will be necessary to understand possible implications of fluoride exposure for the human microbiome. IMPORTANCE Fluoride has been added to drinking water and dental products since the 1950s. The beneficial effects of fluoride on oral health are due to its ability to inhibit the growth of bacteria that cause dental caries. Despite widespread human consumption of fluoride, there have been only two studies of humans that considered the effect of fluoride on human-associated microbial communities, which are increasingly understood to play important roles in health and disease. Notably, neither of these studies included a true cross-sectional control lacking fluoride exposure, as study subjects continued baseline fluoride treatment in their daily dental hygiene routines. To our knowledge, this work (in mice) is the first controlled study to assess the independent effects of fluoride exposure on the oral and gut microbial communities. Investigating how fluoride interacts with host-associated microbial communities in this controlled setting represents an effort toward understanding how common environmental exposures may potentially influence health.

scholarly journals Content of Fluorine in Drinking Water in FYR Macedonia

2014 ◽  
Vol 18 (1) ◽  
pp. 35-37
Author(s):  
M. Carcev ◽  
D. Gjorgev ◽  
F. Tozija ◽  
H. Petanovski
Keyword(s):  
Public Health ◽  
Drinking Water ◽  
Dental Caries ◽  
Water Supply ◽  
Longitudinal Studies ◽  
Optimal Concentration ◽  
Public Water Supply ◽  
The Public ◽  
Who Standards

Abstract From all the methods applied in preventing dental caries, the most significant is the use of fluorides. Nowadays, 6 decades after its massive use, it can certainly be argued that it is the most efficient, cheapest and safest way of preventing dental caries, confirmed by more than 150 longitudinal studies. In order to determine the presence of fluorides in drinking water, in coordination with the Institute for Public Health of the FYR Macedonia in 2009, we conducted a research for determining the presence of fluorides in drinking water from the public water supply in the country. The results from the research showed that concentration of fluorine in drinking water in our country is under 0.3ppm (0.3 mg per litre of water), which indicates a really low amount in accordance to the WHO standards. Optimal concentration was registered in only few water supply facilities in less settled areas, while hyper-fluorinated water was registered in few village wells, which were put out of use after they were located.

Estimation of Fluoride Content of Drinking Water in Dharan

2020 ◽  
Vol 3 (1) ◽  
pp. 88-95
Author(s):  
Bandana Koirala ◽  
Surya Raj Niraula ◽  
Anup Ghimire
Keyword(s):  
Drinking Water ◽  
Dental Caries ◽  
Water Supply ◽  
Optimal Level ◽  
Fluoride Content ◽  
Water Supplies ◽  
Effective Measure ◽  
Guideline Value ◽  
Guideline Values ◽  
Significant Difference

Introduction: Fluoride when present in drinking water at optimal level has been shown to promote oral health by preventing tooth decay. Dental caries represents a health problem that impacts on the medical, functional, nutritional and psychological status of patients in all the age groups. Fluoridation of public water supply is a safe, economical and effective measure to prevent dental caries. Objective: To estimate the level of fluoride present in drinking water supplies in all the wards of Dharan and to compare the fluoride concentration of its different water supply sources. Methods: One hundred water samples were collected from the various sources (ground water and surface water) and its different reservoirs along with random samples of 2-7 from all the wards of Dharan. The samples were then taken to the SEAM-N-MMA laboratory, Biratnagar to be tested for fluoride using the photometric method. Microsoft excel for data entry and SPSS 11.5 version for analysis were used. Significance of the variables was examined by Chi-square test. Results: The results of this study showed that in 96% of the samples taken, fluoride level was below the optimal. Only few samples met the lower range guideline value of Nepal (0.5 mg/l). Also, there was significant difference (p< 0.002) between the surface and consumer level fluoride. Conclusion: The fluoride content in drinking water supplies of Dharan was found to be below optimal level as per the national and WHO guideline values.

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