In vitro Effects of Sodium Lauryl Sulfate on DNA Synthesis and Fine Structure of Human Thymocytes

1986 ◽  
Vol 81 (2) ◽  
pp. 165-169 ◽  
Author(s):  
K. Nordlind ◽  
J. Thyberg
Keyword(s):  
Fine Structure ◽  
Dna Synthesis ◽  
Sodium Lauryl Sulfate ◽  
Lauryl Sulfate ◽  
In Vitro Effects

Planarian regeneration: in vivo and in vitro effects of calcium and calmodulin on DNA synthesis

1983 ◽  
Vol 13 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Isabelle Martelly ◽  
Annie Molla ◽  
Monique Thomasset ◽  
Albert Le Moigne
Keyword(s):  
Dna Synthesis ◽  
Planarian Regeneration ◽  
In Vitro Effects

AMPHOTERICIN B TOPICAL EXTEMPORANEOUS PREPARATIONS FOR THE TREATMENT OF NON-DERMATOPHYTIC ONYCHOMYCOSIS

2020 ◽  
pp. 135-139
Author(s):  
KOMESMUNEEBORIRAK PHOJANA ◽  
WERAWATGANONE PORNPEN ◽  
MUANGSIRI WALAISIRI
Keyword(s):  
Amphotericin B ◽  
Chemical Stability ◽  
High Performance ◽  
Sodium Lauryl Sulfate ◽  
Physical Stability ◽  
Lauryl Sulfate ◽  
Physical And Chemical ◽  
Injection Product

Objective: At present, the nail preparation to cure onychomycosis, caused by non-dermatophyte molds, is not commercially available in Thailand. The physical and chemical stability of amphotericin B (AmB) extemporaneous preparations in the presence of 30% dimethyl sulfoxide (DMSO) and their in vitro nail permeation was evaluated. Methods: AmB extemporaneous preparations in the presence of 30% DMSO were prepared from a commercial sterile injection product, and cream or hydrophilic ointment. Physical stability was tested at 30°C for 2 months, or using 6 heating-cooling cycles. The chemical stability and in vitro nail permeation of AmB content were analyzed using high-performance liquid chromatography (HPLC). In vitro nail permeation was performed by applying 3.5 mg/mm2 of the tested formulation on nail clippings for 5 consecutive days. Results: The AmB cream and ointment extemporaneous preparations containing 30% DMSO, a permeation enhancer, were homogeneous and pale yellow to yellow cream or ointment. The AmB ointment was stable for up to 60 days. The ointment preparation allows in vitro penetration through nails up to 14.17 μg/cm2. The ointment preparation allows significantly better penetration through than the cream preparation due to the presence of DMSO, sodium lauryl sulfate (SLS), and water in the ointment preparation. Conclusion: The AmB extemporaneous ointment was successfully compounded from a commercial sterile injection product with a beyond-use date of 60 days. The ointment preparation is currently under further investigation for in vivo efficacy.

scholarly journals Effect of Sodium Lauryl Sulfate-Fumaric Acid Coupled Addition on theIn VitroRumen Fermentation with Special Regard to Methanogenesis

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
M. A. Abdl-Rahman ◽  
F. A. R. Sawiress ◽  
A. M. Abd El-Aty
Keyword(s):  
Fumaric Acid ◽  
Sodium Lauryl Sulfate ◽  
Volatile Fatty Acids ◽  
Ph Value ◽  
Rumen Fluid ◽  
Negative Control ◽  
Gas Production ◽  
Lauryl Sulfate ◽  
Decremental Effect

The aim of the current study was to evaluate the effect of sodium lauryl sulfate-fumaric acid coupled addition onin vitromethangenesis and rumen fermentation. Evaluation was carried out usingin vitrogas production technique. Ruminal contents were collected from five steers immediately after slaughtering and used for preparation of inoculums of mixed rumen microorganisms. Rumen fluid was then mixed with the basal diet of steers and used to generate four treatments, negative control (no additives), sodium lauryl sulfate (SLS) treated, fumaric acid treated, and SLS-fumaric acid coupled addition treated. The results revealed that, relative to control, efficiency in reduction of methanogenesis was as follows: coupled addition > SLS-addition > fumaric acid addition. Both SLS-addition and SLS-fumaric acid coupled addition demonstrated a decremental effect on ammonia nitrogen (–), total short chain volatile fatty acids (SCVFAs) concentrations and the amount of substrate degraded, and an increment effect on microbial mass and microbial yield (). Nevertheless, fumaric acid did not alter any of the previously mentioned parameters but induced a decremental effect on –. Furthermore, both fumaric acid and SLS-fumaric acid coupled addition increased propionate at the expense of acetate and butyrate, while, defaunation increased acetate at the expense of propionate and butyrate. The pH value was decreased by all treatments relative to control, while, cellulase activity did not differ by different treatments. The current study can be promising strategies for suppressing ruminal methane emissions and improving ruminants feed efficiency.

Effect of Sodium Lauryl Sulfate on the Deposition of Alkali-Soluble Fluoride on Enamel in vitro

1988 ◽  
Vol 22 (3) ◽  
pp. 139-144 ◽  
Author(s):  
P. Barkvoll ◽  
G. Rølla ◽  
F. Lagerlöf
Keyword(s):  
Sodium Lauryl Sulfate ◽  
Lauryl Sulfate
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