scholarly journals Dietary Fat and Coronary Heart Disease: Summary of Evidence from Prospective Cohort and Randomised Controlled Trials

2009 ◽  
Vol 55 (1-3) ◽  
pp. 173-201 ◽  
Author(s):  
C. Murray Skeaff ◽  
Jody Miller
2016 ◽  
Vol 5 ◽  
Author(s):  
Kathy Musa-Veloso ◽  
Lina Paulionis ◽  
Theresa Poon ◽  
Han Youl Lee

AbstractA systematic review and meta-analysis of randomised controlled trials was undertaken to determine the effects of almond consumption on blood lipid levels, namely total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), TAG and the ratios of TC:HDL-C and LDL-C:HDL-C. Following a comprehensive search of the scientific literature, a total of eighteen relevant publications and twenty-seven almond-control datasets were identified. Across the studies, the mean differences in the effect for each blood lipid parameter (i.e. the control-adjusted values) were pooled in a meta-analysis using a random-effects model. It was determined that TC, LDL-C and TAG were significantly reduced by −0·153 mmol/l (P < 0·001), −0·124 mmol/l (P = 0·001) and −0·067 mmol/l (P = 0·042), respectively, and that HDL-C was not affected (−0·017 mmol/l; P = 0·207). These results are aligned with data from prospective observational studies and a recent large-scale intervention study in which it was demonstrated that the consumption of nuts reduces the risk of heart disease. The consumption of nuts as part of a healthy diet should be encouraged to help in the maintenance of healthy blood lipid levels and to reduce the risk of heart disease.


Open Heart ◽  
2015 ◽  
Vol 2 (1) ◽  
pp. e000196 ◽  
Author(s):  
Zoë Harcombe ◽  
Julien S Baker ◽  
Stephen Mark Cooper ◽  
Bruce Davies ◽  
Nicholas Sculthorpe ◽  
...  

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