Quantitative Determination of the Bacteriostatically Active Fraction of Sulfonamides and the Sum of their Inactive Metabolites in the Body Fluids

Chemotherapy ◽  
1972 ◽  
Vol 17 (1) ◽  
pp. 1-21 ◽  
Author(s):  
J. Rieder
Keyword(s):  
Quantitative Determination ◽  
Body Fluids ◽  
The Body ◽  
Active Fraction

Determination of disulfoton and its metabolites in the body fluids of a Di-Syston® intoxication case

1990 ◽  
Vol 48 (2) ◽  
pp. 145-154 ◽  
Author(s):  
M Yashiki ◽  
T Kojima ◽  
M Ohtani ◽  
F Chikasue ◽  
T Miyazaki
Keyword(s):  
Body Fluids ◽  
The Body

scholarly journals Methodology for the quantitative determination of fenbendazole and its metabolites in organs and tissues of animals by high performance liquid chromatography with tandem mass spectrometry detection

2021 ◽  
Vol 15 (4) ◽  
pp. 43-50
Author(s):  
A. I. Varlamova ◽  
V. E. Abramov ◽  
I. A. Arkhipov
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Quantitative Determination ◽  
High Performance ◽  
Supramolecular Complex ◽  
The Body ◽  
Tandem Mass

The purpose of the research is to develop a methodology for the quantitative determination of fenbendazole (FBZ) and its metabolites in organs and tissues of sheep by high performance liquid chromatography tandem mass-spectrometry (HPLC-MS/MS).Materials and methods. The method for determining of FBZ and its metabolites after the administration of the supramolecular complex of fenbendazole was validated in accordance with international guidelines for the following indicators: linearity, recovery, specificity, precision, accuracy, limits of quantitative and qualitative determination.Results and discussion. The method of quantitative analysis of FBZ and its metabolites sulfone and sulfoxide in the body of sheep after the administration of the supramolecular complex has been adapted. The proposed method has a linear relationship (R > 0.99) in the range of 5–1000 ng / g and has shown a good reproducibility and accuracy.

Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC–MS/MS detection

2011 ◽  
Vol 879 (24) ◽  
pp. 2403-2415 ◽  
Author(s):  
S. De Baere ◽  
J. Goossens ◽  
A. Osselaere ◽  
M. Devreese ◽  
V. Vandenbroucke ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Body Fluids ◽  
Animal Body ◽  
Ms Detection

scholarly journals A focus on homocysteine in autism.

2013 ◽  
Vol 60 (2) ◽  
Author(s):  
Joanna Kałużna-Czaplińska ◽  
Ewa Żurawicz ◽  
Monika Michalska ◽  
Jacek Rynkowski
Keyword(s):  
Human Physiology ◽  
Folic Acid ◽  
Dietary Habits ◽  
Biological Fluids ◽  
Body Fluids ◽  
The Body ◽  
Autistic Children ◽  
Pathological Conditions ◽  
Wide Range

Homocysteine is an amino acid, which plays several important roles in human physiology. A wide range of disorders, including neuropsychiatric disorders and autism, are associated with increased homocysteine levels in biological fluids. Various B vitamins: B6 (pyridoxine), B12 (cobalamin), and B9 (folic acid) are required as co-factors by the enzymes involved in homocysteine metabolism. Therefore, monitoring of homocysteine levels in body fluids of autistic children can provide information on genetic and physiological diseases, improper lifestyle (including dietary habits), as well as a variety of pathological conditions. This review presents information on homocysteine metabolism, determination of homocysteine in biological fluids, and shows abnormalities in the levels of homocysteine in the body fluids of autistic children.

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