Effect of Atropine on Pancreatic Secretion in Conscious Rats

Digestion ◽  
1986 ◽  
Vol 33 (1) ◽  
pp. 17-25 ◽  
Author(s):  
Akos Pap ◽  
Henri Sarles
Keyword(s):  
Pancreatic Secretion ◽  
Conscious Rats

scholarly journals Inhibitory Effect of Central Calcitonin-Gene Related Peptide (CGRP) on Pancreatic Secretion in Conscious Rats.

2000 ◽  
Vol 50 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Setsuko Kanai ◽  
Masao Masuda ◽  
Shinji Suzuki ◽  
Minoru Ohta ◽  
Yuki Yoshida ◽  
...  
Keyword(s):  
Pancreatic Secretion ◽  
Inhibitory Effect ◽  
Calcitonin Gene Related Peptide ◽  
Conscious Rats ◽  
Related Peptide ◽  
Calcitonin Gene

STIMULATORY EFFECT OF N-METHYLTYRAMINE, A CONGENER OF BEER, ON PANCREATIC SECRETION IN CONSCIOUS RATS

Pancreas ◽  
2005 ◽  
Vol 31 (4) ◽  
pp. 456
Author(s):  
K Miyasaka ◽  
S Kanai ◽  
M Ohta ◽  
E Tsutumi ◽  
S Suwa
Keyword(s):  
Pancreatic Secretion ◽  
Conscious Rats

Inhibitory effect of central dopamine on basal pancreatic secretion in conscious rats

1998 ◽  
Vol 274 (1) ◽  
pp. G29-G34 ◽  
Author(s):  
Masao Masuda ◽  
Setsuko Kanai ◽  
Kyoko Miyasaka
Keyword(s):  
Pancreatic Secretion ◽  
Sch 23390 ◽  
Sympathetic Nerves ◽  
Inhibitory Effect ◽  
Exocrine Secretion ◽  
External Jugular Vein ◽  
Pancreatic Exocrine Secretion ◽  
Conscious Rats ◽  
Brain Ventricle ◽  
Pancreatic Exocrine

We examined the role and the peripheral mechanism of action of central dopamine on basal pancreatic exocrine secretion in conscious rats. Rats were fitted with bile and pancreatic catheters to collect bile and pancreatic juice separately and also with a left lateral brain ventricle and external jugular vein catheters. After 90-min basal collection, the D1- and D2-receptor antagonists (Sch-23390 and eticlopride, respectively) and dopamine were administered into the lateral brain ventricle. Sch-23390 (30, 100, and 300 nmol/rat), but not eticlopride (300 nmol/rat), stimulated pancreatic fluid and protein secretion. Dopamine (30, 100, and 300 nmol/rat) inhibited pancreatic secretion dose dependently. Pretreatment with Sch-23390 prevented the inhibitory effect of dopamine. Intravenously injected Sch-23390 or dopamine had no effect on pancreatic secretion. The inhibitory effect of dopamine was blocked by bretylium, an inhibitor of norepinephrine release, and phentolamine, an α-blocker, but not by vagotomy. The β-antagonist propranolol alone significantly inhibited basal pancreatic secretion, and dopamine did not modify the inhibitory effect of propranolol. The proton pump inhibitor omeprazole partially but not completely reduced the inhibition by dopamine. These results suggest that central dopamine inhibits pancreatic exocrine secretion via D1-like receptors and that the inhibitory effect is mediated via sympathetic nerves, especially α-adrenoceptors.

Role of Secretin in Basal and Fat-Stimulated Pancreatic Secretion in Conscious Rats*

Endocrinology ◽  
1991 ◽  
Vol 128 (2) ◽  
pp. 979-982 ◽  
Author(s):  
DIFU GUAN ◽  
ALAN SPANNAGEL ◽  
HIDEKI OHTA ◽  
IKUTA NAKANO ◽  
WILLIAM Y. CHEY ◽  
...  
Keyword(s):  
Pancreatic Secretion ◽  
Conscious Rats

Stimulatory Effect ofN-Methyltyramine, a Congener of Beer, on Pancreatic Secretion in Conscious Rats

2010 ◽  
Vol 34 ◽  
pp. S14-S17 ◽  
Author(s):  
Eri Tsutsumi ◽  
Setsuko Kanai ◽  
Minoru Ohta ◽  
Yoshihide Suwa ◽  
Kyoko Miyasaka
Keyword(s):  
Pancreatic Secretion ◽  
Conscious Rats

scholarly journals Pancreatic Response of Anaesthetized and Conscious Rats to Bolus Injection of Cholecystokinin-Pancreozymin

1981 ◽  
Vol 34 (3) ◽  
pp. 283 ◽  
Author(s):  
PS Oates ◽  
RGH Morgan
Keyword(s):  
Pancreatic Duct ◽  
Intravenous Injection ◽  
Pancreatic Secretion ◽  
Bolus Injection ◽  
Conscious Rats ◽  
Anaesthetized Rats ◽  
Protein Output

Pancreatic secretion was studied in anaesthetized rats tested immediately after surgery or in conscious rats tested 48 h after the cannulation of the pancreatic duct. Pancreatic flow, protein output and enzyme output were measured over a 30-min period in the unstimulated state and after the intravenous injection of bolus doses of cholecystokinin-pancreozymin (CCK-PZ) ranging from 1�25 to 20 Crick-Harper-Raper units (CHRU). Each animal received three doses of CCK-PZ, as either ascending or descending doses.

Effect of Taurocholate on CCK Release and Pancreatic Secretion Produced by Two CCK-Releasing Peptides in Conscious Rats

Pancreas ◽  
1992 ◽  
Vol 7 (5) ◽  
pp. 536-542 ◽  
Author(s):  
Kyoko Miyasaka ◽  
Akihiro Funakoshi ◽  
Fukuko Shikado ◽  
Kenichi Uda ◽  
Kenichi Kitani
Keyword(s):  
Pancreatic Secretion ◽  
Conscious Rats ◽  
Cck Release
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