Measurement of 5-Androsten-3β, 17β-diol in Spermatic and Peripheral Venous Blood Samples from the Same Human Subjects by a Radioimmunoassay Method

1978 ◽  
Vol 9 (4) ◽  
pp. 194-200 ◽  
Author(s):  
G. Forti ◽  
E. Calabresi ◽  
P. Giannotti ◽  
D. Borrelli ◽  
P. Gonnelli ◽  
...  
Keyword(s):  
Human Subjects ◽  
Venous Blood ◽  
Blood Samples ◽  
Peripheral Venous Blood ◽  
Radioimmunoassay Method

Direct Measurement of the Hepatointestinal Extraction of Zinc in Cirrhosis and Hepatitis

1981 ◽  
Vol 61 (4) ◽  
pp. 441-444 ◽  
Author(s):  
P. W. N. Keeling ◽  
W. Ruse ◽  
J. Bull ◽  
B. Hannigan ◽  
R. P. H. Thompson
Keyword(s):  
Chronic Hepatitis ◽  
Statistical Significance ◽  
Venous Blood ◽  
Zinc Content ◽  
Atomic Absorption Spectrophotometry ◽  
Zinc Extraction ◽  
Blood Samples ◽  
Peripheral Venous Blood ◽  
Absorption Spectrophotometry ◽  
Biopsy Specimens

1. 65Zn was injected intravenously during transjugular liver biopsy and, from simultaneous hepatic and peripheral venous blood samples, hepatointestinal 65Zn extraction was calculated. Hepatic zinc content was measured in biopsy specimens. 2. On the same occasion samples of liver tissue were taken and their zinc content was measured by atomic absorption spectrophotometry. 3. Seven patients with cirrhosis had significantly lower hepatic zinc content and hepatointestinal zinc extraction than six control patients with mild liver disease. Six patients with chronic hepatitis had a mean hepatointestinal zinc extraction higher than control patients, whereas their mean hepatic zinc content was lower, although the former difference did not achieve statistical significance. 4. These results demonstrate that hepatointestinal extraction of zinc is impaired in cirrhosis, but not in chronic hepatitis.

PRELIMINARY OBSERVATIONS ON THE RELEASE OF OXYTOCIN AND VASOPRESSIN IN HUMAN SUBJECTS

1960 ◽  
Vol 21 (1) ◽  
pp. 125-128 ◽  
Author(s):  
R. R. CHAUDHURY ◽  
G. F. JOPLIN
Keyword(s):  
Intravenous Injection ◽  
Human Subjects ◽  
Venous Blood ◽  
Blood Levels ◽  
Moderate Severity ◽  
Peripheral Venous Blood ◽  
Vasopressor Activity ◽  
Hypothalamic Damage

SUMMARY 1. Oxytocic and vasopressor activity were found in human peripheral venous blood following overnight dehydration and an intravenous injection of nicotine. 2. The quantities are adequate for investigation of hypothalamic damage of moderate severity. 3. The blood levels of oxytocic activity exceed vasopressor activity.

Failure of exogenous secretin to induce secretion of calcitonin in man

1983 ◽  
Vol 103 (3) ◽  
pp. 355-358 ◽  
Author(s):  
Mats Ericsson ◽  
Bertel Berg ◽  
Stig Ingemansson ◽  
Bertil Månsson ◽  
Anders Nobin
Keyword(s):  
Thyroid Gland ◽  
Calcium Level ◽  
Venous Blood ◽  
Human Thyroid ◽  
Parathyroid Surgery ◽  
Peripheral Vein ◽  
Blood Samples ◽  
Peripheral Venous Blood ◽  
Calcitonin Secretion ◽  
Different Doses

Abstract. The effect of secretin on calcitonin secretion from the human thyroid gland was studied in 15 patients undergoing thyroid and parathyroid surgery. Secretin was administered into the inferior thyroid artery at two different doses (0.75 and 7.5 CU) and into a peripheral vein at a dose of 75 CU. Blood samples for measurements of calcitonin and calcium were collected from thyroid or peripheral veins. However, neither intraarterially nor iv administered secretin was able to evoke any significant calcitonin response as measured in thyroid or peripheral venous blood. The calcium level was unaffected by secretin. The results demonstrate that secretin does not act as a calcitonin secretagogue in man.

Regulation of cAMP in a lymphocyte preparation isolated from peripheral venous blood in human subjects: the significance of residual thrombocytes, noradrenaline and prostaglandins

1998 ◽  
Vol 95 (3) ◽  
pp. 377-383 ◽  
Author(s):  
Susanne B. SØNDERGAARD ◽  
Jens H. KNUDSEN ◽  
Niels J. CHRISTENSEN
Keyword(s):  
Healthy Subjects ◽  
Human Subjects ◽  
Venous Blood ◽  
Close Correlation ◽  
Peripheral Venous Blood ◽  
Noradrenaline Concentration ◽  
Noradrenaline And Adrenaline

1.The aim of the study was to elucidate the mechanism of the previously reported close correlation observed between noradrenaline and cAMP in a lymphocyte preparation (LP) isolated from peripheral venous blood in healthy subjects. A close correlation was also obtained in the present study between lymphocyte noradrenaline and adrenaline and cAMP both in the basal state and after stimulation with isoproterenol (P< 0.05 to 0.007). 2.Although 99% of the thrombocytes were removed from the LP during the washing procedure, LP contained approximately one thrombocyte per lymphocyte. The noradrenaline concentration in LP which could be ascribed to residual thrombocytes, calculated from the average noradrenaline concentration in thrombocytes and the number of thrombocytes in LP, correlated closely to noradrenaline in LP (P< 0.007). 3.To test the hypothesis that noradrenaline in LP was primarily derived from plasma, we studied three patients with phaeochromocytoma, who had high levels of noradrenaline and adrenaline both in plasma and in LP. 4.Further studies showed that the addition of thrombocytes to LP increased cAMP. The response was inhibited by indomethacin, whereas the addition of cimetidine and propranolol had no effect on basal or thrombocyte-stimulated cAMP. 5.We conclude that noradrenaline in LP is a marker of the number of residual thrombocytes. The addition of thrombocytes to LP increased cAMP in lymphocytes. This response was not mediated by catecholamines but possibly by prostaglandins.

scholarly journals Can Succinylcholine be Used Safely in Severely Burn Patients?

2012 ◽  
Vol 30 (1) ◽  
pp. 5-9
Author(s):  
H Begum ◽  
MS Islam ◽  
UHS Khatun
Keyword(s):  
Prospective Study ◽  
Surface Area ◽  
Standard Dose ◽  
Venous Blood ◽  
Burn Patients ◽  
Blood Samples ◽  
Peripheral Venous Blood ◽  
Haemodynamic Parameters ◽  
High Level ◽  
Flame Burn

The use of succinylcholine(SC) in burn patients arerelatively contraindicated for certain period after lesion aged4 days – 10 weeks due to chance of hyperkalemia althoughthere are no systemic data to define what period and whatlevel of K+ is safe. This prospective study was carried out in60 acute burn patients who were admitted in DMCH BurnUnit and undergone surgery within 3 months of lesion. Mostcommon type of burn was flame burn (33%).Mean age ofthe patient was 22.60 ± 9.61, TBSA (Total burn surface area)was 22.17 ± 9.57 and duration of burn was 23.36 ± 19.61.Every patient received standard dose of SC (1.5mg/kg) forintubation. The peripheral venous blood samples for serumK+, Na+, Cl - & HCO3- were drawn before induction and 3minutes after injection of SC. On analysis there were nosignificant change of serum K+ and HCO3- (p > .05), on theother hand serum Na+and Cl- levels were significantlychanged (p<0.05) due to correction of dehydration. In caseof electric burn serum K+ level was raised in every casesbut didn’t cross the normal high level of serum K+ (5.5mEq/l). Haemodynamic parameters like pulse, NIBP, SPO2 andECG were analyzed intra operatively and there were nosignificant change in NIBP and ECG, rather there weresignificant improvement in pulse and SPO2 (p< 0.05).Survival of anaesthetic was 100% and no dysrhythmias ormajor morbidity were found intra operatively. Therefore,these data taken in the context of a compelling case forrapid intubating condition suggest safety in succinylcholineuse in the patients with acute burn.   DOI: http://dx.doi.org/10.3329/jbcps.v30i1.11360   J Bangladesh Coll Phys Surg 2012; 30: 5-9

Nucleated Erythrocytes in Enriched and Unenriched Peripheral Venous Blood Samples from Pregnant and Nonpregnant Women

1994 ◽  
Vol 9 (5) ◽  
pp. 291-295 ◽  
Author(s):  
Anna Slunga-Tallberg ◽  
Maija Wessman ◽  
Kari Ylinen ◽  
Harriet von Koskull ◽  
Sakari Knuutila
Keyword(s):  
Venous Blood ◽  
Blood Samples ◽  
Peripheral Venous Blood

Measurement of parathyrin in blood from thyroid veins: two radioimmunoassays compared in patients with primary hyperparathyroidism.

1988 ◽  
Vol 34 (10) ◽  
pp. 2148-2150
Author(s):  
M Muñoz-Torres ◽  
J Diaz ◽  
F Escobar-Jimenez ◽  
G Gonzalez-Calvin ◽  
C Vara ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Venous Blood ◽  
Terminal Region ◽  
The Other ◽  
Multiple Correlation ◽  
Blood Samples ◽  
Peripheral Venous Blood ◽  
Parathyroid Adenomas ◽  
Carboxy Terminal Region ◽  
Carboxy Terminal

Abstract We measured parathyrin (PTH) in peripheral venous blood samples and in thyroid veins (both homolateral and contralateral to the lesion) in 13 patients with surgically confirmed parathyroid adenomas. Two different RIAs were used, one specific to the mid-region of the molecule (44-68, M-PTH), the other specific to the carboxy-terminal region (65-84, C-PTH). With the M-PTH assay we established a statistically significant multiple correlation (P less than 0.05) between the PTH concentrations in blood from the peripheral and thyroid veins; no significant correlation was found when we used the C-PTH assay. Our results confirm the superiority of the M-PTH RIA over the C-PTH RIA for study of hormonal secretion in primary hyperparathyroidism.

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