Bile Acids and Cancer of the Large Bowel

1987 ◽  
Vol 5 (2) ◽  
pp. 65-77 ◽  
Author(s):  
Norbert F. Breuer ◽  
Harald Goebell
Keyword(s):  
1985 ◽  
Vol 28 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Tomio Narisawa ◽  
Masanori Sano ◽  
Makoto Sato ◽  
Toshio Takahashi ◽  
Noritoshi Tanida ◽  
...  

The Lancet ◽  
1975 ◽  
Vol 305 (7906) ◽  
pp. 535-539 ◽  
Author(s):  
M.J. Hill ◽  
B.S. Drasar ◽  
R.E.O. Williams ◽  
T.W. Meade ◽  
A.G. Cox ◽  
...  

2006 ◽  
Vol 95 (6) ◽  
pp. 1063-1074 ◽  
Author(s):  
Gisela Jacobasch ◽  
Gerhard Dongowski ◽  
Detlef Schmiedl ◽  
Katrin Müller-Schmehl

Annealing and heat-moisture treatment (HMT) are shown to be suitable methods to increase the yield of resistant starch type 3 (RS3) from Novelose 330 by up to 75%. Peak temperatures of approximately 121°C were used to produce to a sufficiently high thermal stability of the hydrothermal modified RS3 products for a wide range of applications. HMT significantly increased the crystallinity up to 40%.An in vivofeeding experiment with Wistar rats showed that fermentation of Novelose 330 dominated in the proximal colon, but degradation of HMT-Novelose was more dominant in the distal colon, leading to higher butyrate concentrations in this segment of the large bowel. Large-bowel surface and crypt length increased in the proximal colon in rats fed the Novelose 330-containing diet. In contrast, after the intake of HMT-Novelose, maximal values were found in the distal segment. The lower pH and higher butyrate concentration of the caecal and colonic contents significantlysuppressed the formation of secondary bile acids in RS3-fed rats. The formation of secondary bile acids was inhibited more strongly by HMT-Novelose than by Novelose 330. The Ki-67-immunopositive epithelial cells in the colon of RS3-fed rats indicated the establishment of an optimalbalance in the dynamic process of mucosal regeneration. HMT provides a method for the economical production of a high-quality RS3 with dominating prebiotic properties in the distal colon for health-promoting applications.


Oncology ◽  
1983 ◽  
Vol 40 (4) ◽  
pp. 255-258 ◽  
Author(s):  
Nobuaki Kaibara ◽  
Toshiaki Sasaki ◽  
Masahide Ikeguchi ◽  
Shigemasa Koga ◽  
Shiro Ikawa

1990 ◽  
Vol 2 (4) ◽  
pp. 52-55
Author(s):  
Guonguang Feng ◽  
Xigeng Zhou ◽  
Baoming Yu ◽  
Cairu Dong ◽  
Ruiting Shi ◽  
...  

1978 ◽  
Vol 13 (3) ◽  
pp. 206-212 ◽  
Author(s):  
Tomio Narisawa ◽  
Bandaru S. Reddy ◽  
John H. Weisburger

1984 ◽  
Vol 12 (6) ◽  
pp. 1134-1135 ◽  
Author(s):  
R. WAIT ◽  
M. H. THOMPSON

1968 ◽  
Vol 47 (9) ◽  
pp. 2070-2078 ◽  
Author(s):  
Paul Samuel ◽  
George M. Saypol ◽  
Edward Meilman ◽  
Erwin H. Mosbach ◽  
Mohsen Chafizadeh
Keyword(s):  

1999 ◽  
Vol 8 (5) ◽  
pp. 409-416 ◽  
Author(s):  
P Roy ◽  
R W Owen ◽  
J faivre ◽  
W Scheppach ◽  
M H Saldanha ◽  
...  

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