The Phagocytic Function of the Reticuloendothelial System in Rats Treated with Polybrene®, Liquoid® and Compound 48/80

Pharmacology ◽  
1968 ◽  
Vol 1 (4) ◽  
pp. 253-262 ◽  
Author(s):  
G. Lázár ◽  
F. Biliczki ◽  
K. Kovács
1988 ◽  
Vol 45 (3) ◽  
pp. 314-319 ◽  
Author(s):  
Shigeki Arii ◽  
Kazunobu Monden ◽  
Shigeyuki Itai ◽  
Tetsu Sasaoki ◽  
Masafumi Shibagaki ◽  
...  

1978 ◽  
Vol 56 (6) ◽  
pp. 1055-1057 ◽  
Author(s):  
Daniel J. Loegering ◽  
Marlowe J. Schneidkraut

This study was carried out to determine if reticuloendothelial system (RES) Mockade-induced depletion of circulating alpha-2-glycoprotein opsonic activity resulted in increased susceptibility to hemorrhagic shock. RES blockade induced by the injection of gelatinized lipid emulsion was associated with a 45.9% decrease in phagocytic index and a 85.7% decrease in plasma alpha-2-glycoprotein opsonic activity. Animals subjected to RES blockade 30 min prior to hemorrhagic shock showed a decrease in time to decompensation and a decrease in maximum shed volume. These results are consistent with the concept that circulating levels of this opsonic protein are important in modulating RES phagocytic function and in host defense to shock.


1967 ◽  
Vol 46 (5) ◽  
pp. 855-862 ◽  
Author(s):  
John N. Sheagren ◽  
Jerome B. Block ◽  
Sheldon M. Wolff

1986 ◽  
Vol 25 (01) ◽  
pp. 15-18 ◽  
Author(s):  
M. Luostarinen ◽  
M Vorne ◽  
T. Lantto

Summary 99mTc tin colloid accumulated in the lungs in 102 patients during liver imaging both in malignant and benign diseases. The percentage of neoplastic diseases increased when the lung uptake became greater and only patients with malignant final diagnosis had marked lung uptake. Abnormal liver image was seen only in 23%, which disagrees highly with some earlier findings on a rather small number of patients. The cause of increased lung uptake was suggested to be the activation of the reticuloendothelial system (RES) by disease. The activation of the RES was stronger in malignant than in benign diseases. Some type of regional stimulation of the RES was suggested as being due to the location of the disease and both malignant and benign diseases of the chest region stimulated the pulmonary part of the RES more than other parts of the RES.


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