Use of microorganisms for determination of the phagocytic function of the reticuloendothelial system

1964 ◽  
Vol 55 (2) ◽  
pp. 227-229
Author(s):  
N. A. Kalinina
1988 ◽  
Vol 45 (3) ◽  
pp. 314-319 ◽  
Author(s):  
Shigeki Arii ◽  
Kazunobu Monden ◽  
Shigeyuki Itai ◽  
Tetsu Sasaoki ◽  
Masafumi Shibagaki ◽  
...  

1978 ◽  
Vol 56 (6) ◽  
pp. 1055-1057 ◽  
Author(s):  
Daniel J. Loegering ◽  
Marlowe J. Schneidkraut

This study was carried out to determine if reticuloendothelial system (RES) Mockade-induced depletion of circulating alpha-2-glycoprotein opsonic activity resulted in increased susceptibility to hemorrhagic shock. RES blockade induced by the injection of gelatinized lipid emulsion was associated with a 45.9% decrease in phagocytic index and a 85.7% decrease in plasma alpha-2-glycoprotein opsonic activity. Animals subjected to RES blockade 30 min prior to hemorrhagic shock showed a decrease in time to decompensation and a decrease in maximum shed volume. These results are consistent with the concept that circulating levels of this opsonic protein are important in modulating RES phagocytic function and in host defense to shock.


1967 ◽  
Vol 46 (5) ◽  
pp. 855-862 ◽  
Author(s):  
John N. Sheagren ◽  
Jerome B. Block ◽  
Sheldon M. Wolff

1962 ◽  
Vol 202 (4) ◽  
pp. 704-706 ◽  
Author(s):  
Allan E. Dumont ◽  
Simon H. Stertzer ◽  
John H. Mulholland

Conversion of heme to bilirubin is believed to occur in the cells of the reticuloendothelial system (RES). Use of RES blocking agents in experiments designed to confirm this hypothesis has resulted in data that are equivocal. Determination of bilirubin in thoracic duct lymph provides a more sensitive guide to bilirubin production, in the presence of extrahepatic biliary obstruction, than studies of serum bilirubin alone. In the present report the effect of Thorotrast on bilirubin levels in the thoracic duct lymph and sera has been determined in dogs with experimental biliary obstruction. The results indicate that Thorotrast stops the production of bilirubin and support the view that the normal site of bile pigment production is the RES.


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