Identification of cell surface polypeptides encoded by human chromosomes 2 and 5 in human-mouse somatic cell hybrids

1983 ◽  
Vol 35 (3) ◽  
pp. 226-232
Author(s):  
C.R. Carlin
Keyword(s):  
Cell Surface ◽  
Somatic Cell ◽  
Human Chromosomes ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell

scholarly journals Multiple human beta interferon genes.

1982 ◽  
Vol 156 (3) ◽  
pp. 744-755 ◽  
Author(s):  
A D Sagar ◽  
P B Sehgal ◽  
D L Slate ◽  
F H Ruddle
Keyword(s):  
Somatic Cell ◽  
Human Chromosomes ◽  
Somatic Cell Hybrids ◽  
Diploid Fibroblasts ◽  
Mrna Species ◽  
Human Diploid Fibroblasts ◽  
Beta Interferon ◽  
Cell Hybrids ◽  
Marked Cell ◽  
Mouse Somatic Cell

Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.

scholarly journals Complement-mediated antiserum cytotoxic reactions to human chromosome 7 coded antigen(s): immunoselection of rearranged human chromosome 7 in human-mouse somatic cell hybrids.

1977 ◽  
Vol 145 (2) ◽  
pp. 314-326 ◽  
Author(s):  
B B Knowles ◽  
D Solter ◽  
G Trinchieri ◽  
K M Maloney ◽  
S R Ford ◽  
...  
Keyword(s):  
Cell Surface ◽  
Human Chromosome ◽  
Somatic Cell ◽  
Surface Antigen ◽  
Chromosome 7 ◽  
Cell Surface Antigen ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Human Chromosome 7 ◽  
Mouse Somatic Cell

Immunoselection via complement-dependent lysis of human-mouse somatic cell hybrids containing chromosome 7, with antisera reactive to cell surface antigen(s) coded for by chromosome 7, has resulted in growth of somatic cell hybrids containing rearranged human chromosome 7s. Investigation of these hybrids has localized the gene(s) coding for the relevant cell surface antigen(s) to the short arm of human chromosome 7. The simian virus 40 integration site and the gene coding for human beta-glucuronidase appear to be localized to the long arm of chromosome 7 in this hybrid clone.

Genetic Analysis with Man–Mouse Somatic Cell Hybrids: Linkage between Human Lactate Dehydrogenase A and B and Peptidase B

Nature ◽  
1970 ◽  
Vol 227 (5255) ◽  
pp. 251-257 ◽  
Author(s):  
F. H. RUDDLE ◽  
V. M. CHAPMAN ◽  
T. R. CHEN ◽  
R. J. KLEBE
Keyword(s):  
Lactate Dehydrogenase ◽  
Genetic Analysis ◽  
Somatic Cell ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell

Localization of genes on human chromosomes by studies of human-Chinese hamster somatic cell hybrids

1973 ◽  
Vol 20 (3) ◽  
pp. 195-202 ◽  
Author(s):  
Ans Jongsma ◽  
Harry Someren ◽  
Andries Westerveld ◽  
Ann Hagemeijer ◽  
Peter Pearson
Keyword(s):  
Somatic Cell ◽  
Chinese Hamster ◽  
Human Chromosomes ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids
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