Quantitative analysis of human chromosome segregation in man-mouse somatic cell hybrids

1976 ◽  
Vol 17 (5) ◽  
pp. 243-253 ◽  
Author(s):  
A.R. Rushton
Keyword(s):  
Quantitative Analysis ◽  
Human Chromosome ◽  
Somatic Cell ◽  
Chromosome Segregation ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell

Regional submapping of human chromosome 6 by the use of human-mouse somatic cell hybrids

1978 ◽  
Vol 22 (1-6) ◽  
pp. 412-414 ◽  
Author(s):  
K.-H. Grzeschik ◽  
A. Mayerová ◽  
K. Bender ◽  
R. Johannsmann
Keyword(s):  
Human Chromosome ◽  
Somatic Cell ◽  
Chromosome 6 ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Human Chromosome 6 ◽  
Mouse Somatic Cell

Chromosome segregation from cell hybrids. III. Segregation is independent of spindle constitution

Genome ◽  
1987 ◽  
Vol 29 (4) ◽  
pp. 528-531 ◽  
Author(s):  
Paula A. Zelesco ◽  
Jennifer A. Marshall Graves
Keyword(s):  
Somatic Cell ◽  
Key Words ◽  
Chromosome Segregation ◽  
Chinese Hamster ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell ◽  
Β Tubulin

Hamster β-tubulin (detected as a mutant subunit that confers Colcemid resistance) is either not expressed or is underexpressed in Chinese hamster–mouse somatic cell hybrids. This selectivity of tubulin expression suggests that a uniparental mouse spindle might preferentially engage mouse chromosomes and lead to loss of hamster chromosomes. However, the repression of hamster tubulin was found to have no bearing on the direction of chromosome segregation occurring in eight hybrids studied, some of which segregated predominantly mouse and others hamster chromosomes. Key words: chromosome segregation, cell hybrids, spindle, tubulin.

Direct assignment of citrate synthase (CS) gene to human chromosome 12 in man-mouse somatic cell hybrids

1977 ◽  
Vol 39 (3) ◽  
pp. 339-344 ◽  
Author(s):  
Lucie M. M. Wijnen ◽  
K. -H. Grezeschik ◽  
P. L. Pearson ◽  
P. Meera Khan
Keyword(s):  
Human Chromosome ◽  
Somatic Cell ◽  
Citrate Synthase ◽  
Chromosome 12 ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell

scholarly journals Complement-mediated antiserum cytotoxic reactions to human chromosome 7 coded antigen(s): immunoselection of rearranged human chromosome 7 in human-mouse somatic cell hybrids.

1977 ◽  
Vol 145 (2) ◽  
pp. 314-326 ◽  
Author(s):  
B B Knowles ◽  
D Solter ◽  
G Trinchieri ◽  
K M Maloney ◽  
S R Ford ◽  
...  
Keyword(s):  
Cell Surface ◽  
Human Chromosome ◽  
Somatic Cell ◽  
Surface Antigen ◽  
Chromosome 7 ◽  
Cell Surface Antigen ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Human Chromosome 7 ◽  
Mouse Somatic Cell

Immunoselection via complement-dependent lysis of human-mouse somatic cell hybrids containing chromosome 7, with antisera reactive to cell surface antigen(s) coded for by chromosome 7, has resulted in growth of somatic cell hybrids containing rearranged human chromosome 7s. Investigation of these hybrids has localized the gene(s) coding for the relevant cell surface antigen(s) to the short arm of human chromosome 7. The simian virus 40 integration site and the gene coding for human beta-glucuronidase appear to be localized to the long arm of chromosome 7 in this hybrid clone.

Genetic Analysis with Man–Mouse Somatic Cell Hybrids: Linkage between Human Lactate Dehydrogenase A and B and Peptidase B

Nature ◽  
1970 ◽  
Vol 227 (5255) ◽  
pp. 251-257 ◽  
Author(s):  
F. H. RUDDLE ◽  
V. M. CHAPMAN ◽  
T. R. CHEN ◽  
R. J. KLEBE
Keyword(s):  
Lactate Dehydrogenase ◽  
Genetic Analysis ◽  
Somatic Cell ◽  
Somatic Cell Hybrids ◽  
Cell Hybrids ◽  
Mouse Somatic Cell

Human chromosome 16 physical map: Mapping of somatic cell hybrids using multiplex PCR deletion analysis of sequence tagged sites

Genomics ◽  
1991 ◽  
Vol 10 (4) ◽  
pp. 1047-1052 ◽  
Author(s):  
Robert I. Richards ◽  
Katherine Holman ◽  
Sharon Lane ◽  
Grant R. Sutherland ◽  
David F. Callen
Keyword(s):  
Human Chromosome ◽  
Somatic Cell ◽  
Multiplex Pcr ◽  
Physical Map ◽  
Deletion Analysis ◽  
Somatic Cell Hybrids ◽  
Chromosome 16 ◽  
Cell Hybrids ◽  
Sequence Tagged Sites
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